Search Results - "Estep, Preston"

Compact, universal DNA microarrays to comprehensively determine transcription-factor binding site specificities by Bulyk, Martha L, Berger, Michael F, Philippakis, Anthony A, Qureshi, Aaron M, He, Fangxue S, Estep, Preston W

“…Transcription factors (TFs) interact with specific DNA regulatory sequences to control gene expression throughout myriad cellular processes. However, the DNA…”
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Transparency is key to ethical vaccine research by Estep, Preston W, Church, George M

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The Price/Earnings Ratio, Growth, and Interest Rates: The Smartest BET by Estep, Preston W.

“…The price/earnings ratio (PE) is the most ubiquitous measure of investment value. It appears to tell us how many years would be required for accumulated…”
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Extensive sequencing of seven human genomes to characterize benchmark reference materials by Zook, Justin M., Catoe, David, McDaniel, Jennifer, Vang, Lindsay, Spies, Noah, Sidow, Arend, Weng, Ziming, Liu, Yuling, Mason, Christopher E., Alexander, Noah, Henaff, Elizabeth, McIntyre, Alexa B.R., Chandramohan, Dhruva, Chen, Feng, Jaeger, Erich, Moshrefi, Ali, Pham, Khoa, Stedman, William, Liang, Tiffany, Saghbini, Michael, Dzakula, Zeljko, Hastie, Alex, Cao, Han, Deikus, Gintaras, Schadt, Eric, Sebra, Robert, Bashir, Ali, Truty, Rebecca M., Chang, Christopher C., Gulbahce, Natali, Zhao, Keyan, Ghosh, Srinka, Hyland, Fiona, Fu, Yutao, Chaisson, Mark, Xiao, Chunlin, Trow, Jonathan, Sherry, Stephen T., Zaranek, Alexander W., Ball, Madeleine, Bobe, Jason, Estep, Preston, Church, George M., Marks, Patrick, Kyriazopoulou-Panagiotopoulou, Sofia, Zheng, Grace X.Y., Schnall-Levin, Michael, Ordonez, Heather S., Mudivarti, Patrice A., Giorda, Kristina, Sheng, Ying, Rypdal, Karoline Bjarnesdatter, Salit, Marc

“…The Genome in a Bottle Consortium, hosted by the National Institute of Standards and Technology (NIST) is creating reference materials and data for human…”
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Short-Term Calorie Restriction in Male Mice Feminizes Gene Expression and Alters Key Regulators of Conserved Aging Regulatory Pathways by Estep, Preston Wayne III, Warner, Jason B, Bulyk, Martha L

“…Background: Calorie restriction (CR) is the only intervention known to extend lifespan in a wide range of organisms, including mammals. However, the mechanisms…”
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Harvard Personal Genome Project: lessons from participatory public research by Ball, Madeleine P, Bobe, Jason R, Chou, Michael F, Clegg, Tom, Estep, Preston W, Lunshof, Jeantine E, Vandewege, Ward, Zaranek, Alexander, Church, George M

“…Since its initiation in 2005, the Harvard Personal Genome Project has enrolled thousands of volunteers interested in publicly sharing their genome, health and…”
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Highly parallel assays of tissue-specific enhancers in whole Drosophila embryos by Gisselbrecht, Stephen S, Barrera, Luis A, Porsch, Martin, Aboukhalil, Anton, Estep, Preston W, Vedenko, Anastasia, Palagi, Alexandre, Kim, Yongsok, Zhu, Xianmin, Busser, Brian W, Gamble, Caitlin E, Iagovitina, Antonina, Singhania, Aditi, Michelson, Alan M, Bulyk, Martha L

“…Identifying tissue-specific expression of a selection marker and putative enhancer-driven expression of GFP with flow cytometry enriches for active enhancers…”
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Declining asexual reproduction is suggestive of senescence in hydra: Comment on Martinez, D., “Mortality patterns suggest lack of senescence in hydra.” Exp Gerontol 33, 217–25 by Estep, Preston W

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Finding DNA regulatory motifs within unaligned noncoding sequences clustered by whole-genome mRNA quantitation by Roth, Frederick P, Hughes, Jason D, Estep, Preston W, Church, George M

“…Whole-genome mRNA quantitation can be used to identify the genes that are most responsive to environmental or genotypic change. By searching for mutually…”
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Regulatory Networks Revealed by Transcriptional Profiling of Damaged Saccharomyces cerevisiae Cells: Rpn4 Links Base Excision Repair with Proteasomes by Jelinsky, Scott A., Estep, Preston, Church, George M., Samson, Leona D.

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Many factors modify the physiological response to sugary liquids by Estep, Preston W

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Selection analyses of insertional mutants using subgenic-resolution arrays by Church, George M, Badarinarayana, Vasudeo, Estep, Preston W, Shendure, Jay, Edwards, Jeremy, Tavazoie, Saeed, Lam, Felix

“…We describe a method of genome-wide analysis of quantitative growth phenotypes using insertional mutagenesis and DNA microarrays. We applied the method to…”
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The whole genome sequences and experimentally phased haplotypes of over 100 personal genomes by Mao, Qing, Ciotlos, Serban, Zhang, Rebecca Yu, Ball, Madeleine P, Chin, Robert, Carnevali, Paolo, Barua, Nina, Nguyen, Staci, Agarwal, Misha R, Clegg, Tom, Connelly, Abram, Vandewege, Ward, Zaranek, Alexander Wait, Estep, Preston W, Church, George M, Drmanac, Radoje, Peters, Brock A

“…Since the completion of the Human Genome Project in 2003, it is estimated that more than 200,000 individual whole human genomes have been sequenced. A stunning…”
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Accelerating Genomic Data Generation and Facilitating Genomic Data Access Using Decentralization, Privacy-Preserving Technologies and Equitable Compensation by Grishin, Dennis, Obbad, Kamal, Estep, Preston, Quinn, Kevin, Zaranek, Sarah Wait, Zaranek, Alexander Wait, Vandewege, Ward, Clegg, Tom, César, Nico, Cifric, Mirza, Church, George

“…In the years since the first human genome was sequenced at a cost of over $3 billion, technological advancements have driven the price below $1,000, making…”
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Cash Flows, Asset Values, and Investment Returns by Estep, Preston W.

“…Most methods for forecasting expected returns of stocks are based on earnings. As analysts have justifiably become somewhat wary of earnings reports, they are…”
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Computational identification of Cis-regulatory elements associated with groups of functionally related genes in Saccharomyces cerevisiae by Hughes, J.D, Estep, P.W, Tavazoie, S, Church, G.M

“…AlignACE is a Gibbs sampling algorithm for identifying motifs that are over-represented in a set of DNA sequences. When used to search upstream of apparently…”
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Many factors modify the physiological response to sugary liquids by Estep, Preston W

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Genomic approaches to connecting the transcriptional regulatory network of Saccharomyces cerevisiae stress responses by Estep, Preston Wayne

“…The yeast Saccharomyces cerevisiae is the leading model organism for study by genomic methods. Whole-genome transcript profile data are now being generated…”
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A New Method for Valuing Common Stocks by Estep, Preston W.

“…A new formula for estimating an investor's expected return--the T-Model--expresses total return in terms of a company's growth rate, its return on equity and…”
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public resource facilitating clinical use of genomes by Ball, Madeleine P, Thakuria, Joseph V, Zaranek, Alexander Wait, Clegg, Tom, Rosenbaum, Abraham M, Wu, Xiaodi, Angrist, Misha, Bhak, Jong, Bobe, Jason, Callow, Matthew J, Cano, Carlos, Chou, Michael F, Chung, Wendy K, Douglas, Shawn M, Estep, Preston W, Gore, Athurva, Hulick, Peter, Labarga, Alberto, Lee, Je-Hyuk, Lunshof, Jeantine E, Kim, Byung Chul, Kim, Jong-Il, Li, Zhe, Murray, Michael F, Nilsen, Geoffrey B, Peters, Brock A, Raman, Anugraha M, Rienhoff, Hugh Y, Robasky, Kimberly, Wheeler, Matthew T, Vandewege, Ward, Vorhaus, Daniel B, Yang, Joyce L, Yang, Luhan, Aach, John, Ashley, Euan A, Drmanac, Radoje, Kim, Seong-Jin, Li, Jin Billy, Peshkin, Leonid, Seidman, Christine E, Seo, Jeong-Sun, Zhang, Kun, Rehm, Heidi L, Church, George M

“…Rapid advances in DNA sequencing promise to enable new diagnostics and individualized therapies. Achieving personalized medicine, however, will require…”
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