Search Results - "Esteban, Roger"
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Molecular classification and therapeutic targets in extrahepatic cholangiocarcinoma
Published in Journal of hepatology (01-08-2020)“…Cholangiocarcinoma (CCA), a deadly malignancy of the bile ducts, can be classified based on its anatomical location into either intrahepatic (iCCA) or…”
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Molecular portrait of high alpha-fetoprotein in hepatocellular carcinoma: implications for biomarker-driven clinical trials
Published in British journal of cancer (13-08-2019)“…The clinical utility of serum alpha-fetoprotein (AFP) in patients with hepatocellular carcinoma (HCC) is widely recognised. However, a clear understanding of…”
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Copy-Number Alteration Burden Differentially Impacts Immune Profiles and Molecular Features of Hepatocellular Carcinoma
Published in Clinical cancer research (01-12-2020)“…Chromosomal instability is a hallmark of cancer that results in broad and focal copy-number alterations (CNAs), two events associated with distinct molecular,…”
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CNApp, a tool for the quantification of copy number alterations and integrative analysis revealing clinical implications
Published in eLife (15-01-2020)“…Somatic copy number alterations (CNAs) are a hallmark of cancer, but their role in tumorigenesis and clinical relevance remain largely unclear. Here, we…”
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Oncogenic role of PMEPA1 and its association with immune exhaustion and TGF-β activation in HCC
Published in JHEP reports (01-11-2024)“…Transforming growth factor β (TGF-β) plays an oncogenic role in advanced cancer by promoting cell proliferation, metastasis and immunosuppression. PMEPA1…”
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EMS mutagenesis in mature seed-derived rice calli as a new method for rapidly obtaining TILLING mutant populations
Published in Plant methods (30-01-2014)“…TILLING (Targeting Induced Local Lesions IN Genomes) is a reverse genetic method that combines chemical mutagenesis with high-throughput genome-wide screening…”
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Isolation and Characterization of a Human Fetal Mesenchymal Stem Cell Population: Exploring the Potential for Cell Banking in Wound Healing Therapies
Published in Cell transplantation (01-11-2019)“…Various cell-based therapies are in development to address chronic and acute skin wound healing, for example for burns and trauma patients. An off-the-shelf…”
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Políticas curriculares. Experiencias en contextos latinoamericanos
Published in Revista complutense de educación (01-10-2021)“…El currículo es inherente a todo sistema educativo, puesto que es la concreción del tipo de ser humano que se desea formar. Los currículos responden a las…”
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Cabozantinib Enhances Anti-PD1 Activity and Elicits a Neutrophil-Based Immune Response in Hepatocellular Carcinoma
Published in Clinical cancer research (01-06-2022)“…Immune checkpoint inhibitors combined with antiangiogenic agents produce benefits in the treatment of advanced hepatocellular carcinoma (HCC). We investigated…”
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Gestión de los posgrados post COVID-19
Published in Revista de ciencias sociales (Maracaibo, Venezuela) (01-09-2021)“…El “fenómeno” COVID-19 aceleró, o hizo más notorias, ciertas tendencias y desafíos de los programas de educación superior en general (Araya-Castillo y…”
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PCIG: a web-based application to explore immune–genomics interactions across cancer types
Published in Bioinformatics (12-04-2022)“…Abstract Motivation Genomic alterations can modulate the tumor immunophenotype depending on their nature and tissue of origin. Although this immune–genomic…”
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Tendencias y desafíos de los programas de posgrado latinoamericanos en contextos de COVID-19
Published in Revista venezolana de gerencia (01-01-2021)“…El presente artículo tiene como propósito revelar las tendencias y desafíos de los programas de posgrado latinoamericanos ante la inminente situación de…”
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Convivencia en las clases virtuales durante confinamiento por covid-19: una mirada desde los estudiantes universitarios
Published in Telos (Maracaibo, Venezuela) (01-09-2022)“…Debido al COVID-19 muchos países prohibieron las reuniones masivas, entre ellas las clases presenciales en todos los niveles educativos. Para no perder el año…”
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Hepatocellular Carcinoma in Mongolia Delineates Unique Molecular Traits and a Mutational Signature Associated with Environmental Agents
Published in Clinical cancer research (14-10-2022)“…Mongolia has the world's highest incidence of hepatocellular carcinoma (HCC), with ∼100 cases/100,000 inhabitants, although the reasons for this have not been…”
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[Reseña del libro] Investigar en la clase de ciencia
Published in Revista iberoamericana de educación (09-09-2021)“…Delod, G. (2020). Investigar en la clase de ciencia. Madrid: Ediciones Morata. 79 páginas. ISBN: 978-84-18381-04-1En el libro la autora reconoce que se han ido…”
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Addition of tyrosine kinase inhibitors (TKIs) in patients (pts) with unresectable hepatocellular carcinoma (HCC) who progress on first-line immunotherapy (IO)
Published in Journal of clinical oncology (01-06-2022)“…e16193 Background: Atezolizumab plus bevacizumab is now standard first-line therapy for advanced HCC. Early phase trials in HCC and phase III trials in other…”
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Training for pedagogical practice with Asperger children
Published in Revista MENDIVE (Online) (01-12-2021)“…In Peru and in the world, the inclusion of students with special educational needs, including children with Asperger's syndrome, in regular basic education is…”
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Gender violence: from the social to university spaces
Published in Revista MENDIVE (Online) (01-06-2022)Get full text
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Gender violence: from social to university spaces/Violencia de género: de lo social a espacios universitarios
Published in Revista MENDIVE (Online) (01-08-2021)Get full text
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