Search Results - "Estcourt, Lise J."
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Multicenter, multidisciplinary user‐centered design of a clinical decision‐support and simulation system for massive transfusion
Published in Transfusion (Philadelphia, Pa.) (01-05-2023)“…Background Managing critical bleeding with massive transfusion (MT) requires a multidisciplinary team, often physically separated, to perform several…”
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Alternatives to allogeneic platelet transfusion
Published in British journal of haematology (01-11-2016)“…Summary Allogeneic platelet transfusions are widely used for the prevention and treatment of bleeding in thrombocytopenia. Recent evidence suggests platelet…”
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Risk of bleeding and use of platelet transfusions in patients with hematologic malignancies: recurrent event analysis
Published in Haematologica (Roma) (01-06-2015)“…A recent randomized trial (TOPPS) compared prophylactic platelet transfusions (for counts <10×10(9)/L) with a strategy of no-prophylaxis in adults with…”
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The TREATT Trial (TRial to EvaluAte Tranexamic acid therapy in Thrombocytopenia): safety and efficacy of tranexamic acid in patients with haematological malignancies with severe thrombocytopenia: study protocol for a double-blind randomised controlled trial
Published in Current controlled trials in cardiovascular medicine (15-10-2019)“…Patients with haematological malignancies often develop thrombocytopenia as a consequence of either their disease or its treatment. Platelet transfusions are…”
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Reply to comment on: Massive transfusion experience, current practice and decision support: A survey of Australian and New Zealand Anaesthetists
Published in Anaesthesia and intensive care (01-07-2022)“…We would like to congratulate Dr Miller and colleagues on developing a smartphone application to provide clinical decision support (CDS) for interpreting…”
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Early, very high-titre convalescent plasma therapy in clinically vulnerable individuals with mild COVID-19 (COVIC-19): protocol for a randomised, open-label trial
Published in BMJ open (27-04-2023)“…IntroductionCOVID-19 convalescent plasma (CCP) is a possible treatment option for COVID-19. A comprehensive number of clinical trials on CCP efficacy have…”
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Massive transfusion experience, current practice and decision support: A survey of Australian and New Zealand anaesthetists
Published in Anaesthesia and intensive care (01-05-2021)“…Massive transfusions guided by massive transfusion protocols are commonly used to manage critical bleeding, when the patient is at significant risk of…”
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The challenges of measuring bleeding outcomes in clinical trials of platelet transfusions
Published in Transfusion (Philadelphia, Pa.) (01-07-2013)“…Background Many platelet (PLT) transfusion trials now use bleeding as a primary outcome; however, previous studies have shown a wide variation in the amount…”
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Changes in Phenotypic and Molecular Features of Naïve and Central Memory T Helper Cell Subsets following SARS-CoV-2 Vaccination
Published in Vaccines (Basel) (11-09-2024)“…Molecular changes in lymphocytes following SARS-CoV-2 vaccination are incompletely understood. We hypothesized that studying the molecular (transcriptomic,…”
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Passive immune therapies: another tool against COVID-19
Published in Hematology (10-12-2021)“…Passive immune therapy consists of several different therapies, convalescent plasma, hyperimmune globulin, and severe acute respiratory syndrome coronavirus 2…”
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Convalescent plasma or hyperimmune immunoglobulin for people with COVID-19: a rapid review
Published in Cochrane database of systematic reviews (14-05-2020)“…Convalescent plasma and hyperimmune immunoglobulin may reduce mortality in patients with respiratory virus diseases, and are currently being investigated…”
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Convalescent plasma or hyperimmune immunoglobulin for people with COVID-19: a living systematic review
Published in Cochrane database of systematic reviews (10-07-2020)“…Convalescent plasma and hyperimmune immunoglobulin may reduce mortality in patients with viral respiratory diseases, and are currently being investigated…”
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Guidelines for the use of platelet transfusions
Published in British journal of haematology (01-02-2017)Get full text
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Convalescent plasma for covid-19
Published in BMJ (Online) (15-09-2020)“…Authorisation in the US was premature, and a missed opportunity…”
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Interventions for improving adherence to iron chelation therapy in people with sickle cell disease or thalassaemia
Published in Cochrane database of systematic reviews (06-03-2023)“…Regularly transfused people with sickle cell disease (SCD) and people with thalassaemia are at risk of iron overload. Iron overload can lead to iron toxicity…”
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Thrombocytopenia in Surgery and Neuraxial Anesthesia
Published in Seminars in thrombosis and hemostasis (01-04-2020)“…This is a review of the evidence for the use of different platelet count thresholds prior to invasive procedures and surgery. This review will focus on three…”
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SARS-CoV-2-neutralising monoclonal antibodies for treatment of COVID-19
Published in Cochrane database of systematic reviews (02-09-2021)“…Monoclonal antibodies (mAbs) are laboratory-produced molecules derived from the B cells of an infected host. They are being investigated as a potential therapy…”
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Convalescent plasma or hyperimmune immunoglobulin for people with COVID-19: a living systematic review
Published in Cochrane database of systematic reviews (20-05-2021)“…Convalescent plasma and hyperimmune immunoglobulin may reduce mortality in patients with viral respiratory diseases, and are being investigated as potential…”
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How should we use convalescent plasma therapies for the management of COVID-19?
Published in Blood (25-03-2021)“…Convalescent plasma (CP) from blood donors with antibodies to severe acute respiratory syndrome coronavirus 2 may benefit patients with COVID-19 by providing…”
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Granulocyte transfusions for treating infections in people with neutropenia or neutrophil dysfunction
Published in Cochrane database of systematic reviews (29-04-2016)“…Despite modern antimicrobials and supportive therapy bacterial and fungal infections are still major complications in people with prolonged disease-related or…”
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