Search Results - "Estévez‐Herrera, Judith"
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ATP: The crucial component of secretory vesicles
Published in Proceedings of the National Academy of Sciences - PNAS (12-07-2016)“…The colligative properties of ATP and catecholamines demonstrated in vitro are thought to be responsible for the extraordinary accumulation of solutes inside…”
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HIV Infection: Shaping the Complex, Dynamic, and Interconnected Network of the Cytoskeleton
Published in International journal of molecular sciences (01-09-2023)“…HIV-1 has evolved a plethora of strategies to overcome the cytoskeletal barrier (i.e., actin and intermediate filaments (AFs and IFs) and microtubules (MTs))…”
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TDP-43 Controls HIV-1 Viral Production and Virus Infectiveness
Published in International journal of molecular sciences (01-04-2023)“…The transactive response DNA-binding protein (TARDBP/TDP-43) is known to stabilize the anti-HIV-1 factor, histone deacetylase 6 (HDAC6). TDP-43 has been…”
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The Interplay of HIV and Autophagy in Early Infection
Published in Frontiers in microbiology (28-04-2021)“…HIV/AIDS is still a global threat despite the notable efforts made by the scientific and health communities to understand viral infection, to design new drugs…”
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Glucagon-like peptide-1 receptor controls exocytosis in chromaffin cells by increasing full-fusion events
Published in Cell reports (Cambridge) (24-08-2021)“…Agonists for glucagon-like-peptide-1 receptor (GLP-1R) are currently used for the treatment of type 2 diabetes and obesity. Their benefits have been centered…”
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Adrenergic chromaffin cells are adrenergic even in the absence of epinephrine
Published in Journal of neurochemistry (01-02-2020)“…Adrenal chromaffin cells release epinephrine (EPI) and norepinephrine (NE) into the bloodstream as part of the homeostatic response to situations like stress…”
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The intravesicular cocktail and its role in the regulation of exocytosis
Published in Journal of neurochemistry (01-06-2016)“…The accumulation of neurotransmitters within secretory vesicles (SVs) far exceeds the theoretical tonic concentrations in the cytosol, a phenomenon that has…”
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Transactive Response DNA-Binding Protein (TARDBP/TDP-43) Regulates Cell Permissivity to HIV-1 Infection by Acting on HDAC6
Published in International journal of molecular sciences (31-05-2022)“…The transactive response DNA-binding protein (TARDBP/TDP-43) influences the processing of diverse transcripts, including that of histone deacetylase 6 (HDAC6)…”
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The Characteristics of the HIV-1 Env Glycoprotein Are Linked With Viral Pathogenesis
Published in Frontiers in microbiology (24-03-2022)“…The understanding of HIV-1 pathogenesis and clinical progression is incomplete due to the variable contribution of host, immune, and viral factors. The…”
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10
Electrochemical Investigation of the Interaction between Catecholamines and ATP
Published in Analytical chemistry (Washington) (06-02-2018)“…The study of the colligative properties of adenosine 5′-triphosphate (ATP) and catecholamines has received the attention of scientists for decades, as they…”
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The ZIKV NS5 Protein Aberrantly Alters the Tubulin Cytoskeleton, Induces the Accumulation of Autophagic p62 and Affects IFN Production: HDAC6 Has Emerged as an Anti-NS5/ZIKV Factor
Published in Cells (Basel, Switzerland) (01-04-2024)“…Zika virus (ZIKV) infection and pathogenesis are linked to the disruption of neurogenesis, congenital Zika syndrome and microcephaly by affecting neural…”
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HIV-1 Nef Targets HDAC6 to Assure Viral Production and Virus Infection
Published in Frontiers in microbiology (30-10-2019)“…HIV Nef is a central auxiliary protein in HIV infection and pathogenesis. Our results indicate that HDAC6 promotes the aggresome/autophagic degradation of the…”
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Potentiation of the Transient Receptor Potential Vanilloid 1 Channel Contributes to Pruritogenesis in a Rat Model of Liver Disease
Published in The Journal of biological chemistry (05-04-2013)“…Persistent pruritus is a common disabling dermatologic symptom associated with different etiologic factors. These include primary skin conditions, as well as…”
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Zika Virus Pathogenesis: A Battle for Immune Evasion
Published in Vaccines (Basel) (22-03-2021)“…Zika virus (ZIKV) infection and its associated congenital and other neurological disorders, particularly microcephaly and other fetal developmental…”
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Contribution of the HIV-1 Envelope Glycoprotein to AIDS Pathogenesis and Clinical Progression
Published in Biomedicines (01-09-2022)“…In the absence of antiviral therapy, HIV-1 infection progresses to a wide spectrum of clinical manifestations that are the result of an entangled contribution…”
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HIV-1 envelope glycoproteins isolated from Viremic Non-Progressor individuals are fully functional and cytopathic
Published in Scientific reports (03-04-2019)“…In untreated HIV-1-infected individuals, viremia is positively associated with disease progression. However, some viremic non progressors (VNPs) individuals…”
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The interaction between chromogranin A and catecholamines governs exocytosis
Published in The FASEB journal (01-11-2014)“…Chromogranins (Cgs) are acidic proteins that have been described in the large, dense core vesicles (LDCVs) of adrenal chromaffin cells and that have been shown…”
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Isolation of mouse chromaffin secretory vesicles and their division into 12 fractions
Published in Analytical biochemistry (01-11-2017)“…The study of chromaffin secretory vesicles (SVs) has contributed immensely to our understanding of exocytosis. These organelles, also called chromaffin…”
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Vesicular Ca2+ mediates granule motion and exocytosis
Published in Cell calcium (Edinburgh) (01-03-2012)“…Abstract Secretory vesicles of chromaffin cells are acidic organelles that maintain an increasing pH gradient towards the cytosol (5.5 vs. 7.3) that is…”
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Nanomaterials to combat SARS-CoV-2: Strategies to prevent, diagnose and treat COVID-19
Published in Frontiers in bioengineering and biotechnology (25-11-2022)“…The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and the associated coronavirus disease 2019 (COVID-19), which severely affect the…”
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