Search Results - "Estévez‐Carrizo, Francisco E."
-
1
Single-Dose Relative Bioavailability of a New Quetiapine Fumarate Extended-Release Formulation: A Postprandial, Randomized, Open-Label, Two-Period Crossover Study in Healthy Uruguayan Volunteers
Published in Clinical therapeutics (01-06-2011)“…Abstract Background Quetiapine is a dibenzothiazepine derivative that has been established as an effective therapy for schizophrenia and bipolar disorder. A…”
Get full text
Journal Article -
2
Bioequivalence of two film-coated tablets of imatinib mesylate 400 mg: A randomized, open-label, single-dose, fasting, two-period, two-sequence crossover comparison in healthy male South American volunteers
Published in Clinical therapeutics (01-10-2009)“…Abstract Background: Imatinib is a tyrosine kinase inhibitor that has been established as a highly effective therapy for chronic myelogenous leukemia and…”
Get full text
Journal Article -
3
Genomic Ancestry, CYP2D6, CYP2C9, and CYP2C19 Among Latin Americans
Published in Clinical pharmacology and therapeutics (01-01-2020)“…We present the distribution of CYP2D6, CYP2C9, and CYP2C19 variants and predicted phenotypes in 33 native and admixed populations from Ibero‐America…”
Get full text
Journal Article -
4
Genomic Ancestry, CYP 2D6 , CYP 2C9 , and CYP 2C19 Among Latin Americans
Published in Clinical pharmacology and therapeutics (01-01-2020)“…We present the distribution of CYP 2D6 , CYP 2C9 , and CYP 2C19 variants and predicted phenotypes in 33 native and admixed populations from Ibero‐America ( n…”
Get full text
Journal Article -
5
Ethnic background and CYP2D6 genetic polymorphisms in Costa Ricans
Published in Revista de biología tropical (01-12-2014)“…CYP2D6 differences have already been demonstrated within Latin American populations by the CEIBA.FP Consortium of the Ibero-American Network of…”
Get full text
Journal Article -
6
Relevance of the ancestry for the variability of the Drug-Metabolizing Enzymes CYP2C9, CYP2C19 and CYP2D6 polymorphisms in a multiethnic Costa Rican population
Published in Revista de biología tropical (01-09-2016)“…CYP2C9, CYP2C19 and CYP2D6 metabolize around 40% of drugs and their genes vary across populations. The Costa Rican population has a trihybrid ancestry and its…”
Get full text
Journal Article -
7
High prevalence of CYP2D6 ultrarapid metabolizers in a mestizo Colombian population in relation to Hispanic mestizo populations
Published in Pharmacogenomics (01-11-2020)“…Interethnic differences in allele frequency have been demonstrated across Latin-American countries. Only one previous study describing genotypes in Colombian…”
Get full text
Journal Article -
8
MDR-1 genotypes and quetiapine pharmacokinetics in healthy volunteers
Published in Drug metabolism and drug interactions (2013)“…P-glycoprotein is an efflux transporter encoded by the multidrug-resistance MDR-1 gene, which influences the absorption and excretion of a variety of drugs…”
Get more information
Journal Article -
9
Pharmacogenetics in Latin American populations: regulatory aspects, application to herbal medicine, cardiovascular and psychiatric disorders
Published in Drug metabolism and drug interactions (01-03-2012)“…Meeting report of the "Second Symposium on Pharmacology of Cytochrome P450 and Transporters" organized by the Cuban Society of Pharmacology in collaboration…”
Get more information
Journal Article