Search Results - "Estévez, Jorge"
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Reference Values on Children's Hair for 28 Elements (Heavy Metals and Essential Elements) Based on a Pilot Study in a Representative Non-Contaminated Local Area
Published in International journal of molecular sciences (01-05-2023)“…Studies have been published, and laboratories offer services of measuring elements in hair as biomarkers of environmental exposure and/or control of essential…”
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A Transcriptomic Analysis of T98G Human Glioblastoma Cells after Exposure to Cadmium-Selenium Quantum Dots Mainly Reveals Alterations in Neuroinflammation Processes and Hypothalamus Regulation
Published in International journal of molecular sciences (18-02-2022)“…Quantum dots are nanoparticles with very promising biomedical applications. However, before these applications can be authorized, a complete toxicological…”
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Titanium Dioxide, but Not Zinc Oxide, Nanoparticles Cause Severe Transcriptomic Alterations in T98G Human Glioblastoma Cells
Published in International journal of molecular sciences (19-02-2021)“…Titanium dioxide and zinc oxide are two of the most widely used nanomaterials. We assessed the effects of noncytotoxic doses of both nanomaterials on T98G…”
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An integrated approach for detecting embryotoxicity and developmental toxicity of environmental contaminants using in vitro alternative methods
Published in Toxicology letters (15-10-2014)“…•Stem cells under differentiation are useful model for testing embryotoxicity in vitro.•Zebra fish and WEC are widely used for testing teratogenicity in…”
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Reliable Lift‐Off Patterning of Graphene Dispersions for Humidity Sensors
Published in Advanced materials interfaces (01-06-2024)“…Dispersion‐based graphene materials are promising candidates for various sensing applications. They offer the advantage of relatively simple and fast…”
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Effect of femtosecond laser-assisted lens surgery on the optic nerve head and the macula
Published in International journal of ophthalmology (18-06-2019)“…To evaluate the effect of femtosecond laser-assisted lens surgery (FLALS; cataract surgery or refractive lens exchange) on the structure of the optic nerve…”
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Investigation of the Effects of Metallic Nanoparticles on Fertility Outcomes and Endocrine Modification of the Hypothalamic-Pituitary-Gonadal Axis
Published in International journal of molecular sciences (01-07-2023)“…Nanotechnology is a very disruptive twenty-first-century revolution that will allow social and economic welfare to increase although it also involves a…”
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Inhibition with simultaneous spontaneous reactivation and aging of acetylcholinesterase by organophosphorus compounds: Demeton-S-methyl as a model
Published in Chemico-biological interactions (05-01-2024)“…The kinetic analysis of esterase inhibition by acylating compounds (organophosphorus, carbamates and sulfonylfluorides) sometimes cannot yield consistent…”
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Interactions of human acetylcholinesterase with phenyl valerate and acetylthiocholine: Thiocholine as an enhancer of phenyl valerate esterase activity
Published in Chemico-biological interactions (05-01-2022)“…Phenyl valerate (PV) is a neutral substrate for measuring the PVase activity of neuropathy target esterase (NTE), a key molecular event of…”
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Case study: Is bisphenol S safer than bisphenol A in thermal papers?
Published in Archives of toxicology (01-07-2019)“…The Risk Assessment Committee of the European Chemical Agency released a scientific opinion alerting that the risk associated with dermal occupational exposure…”
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Effects of silver nanoparticles on T98G human glioblastoma cells
Published in Toxicology and applied pharmacology (01-10-2020)“…Nanotechnology has been well developed in recent decades because it provides social progress and welfare. Consequently, exposure of population is increasing…”
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Phenyl valerate esterase activity of human butyrylcholinesterase
Published in Archives of toxicology (01-10-2017)“…Phenyl valerate is used for detecting and measuring neuropathy target esterase (NTE) and has been used for discriminating esterases as potential target in hen…”
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Phenylmethylsulfonyl Fluoride, a Potentiator of Neuropathy, Alters the Interaction of Organophosphorus Compounds with Soluble Brain Esterases
Published in Chemical research in toxicology (19-11-2012)“…Phenylmethylsulfonyl fluoride (PMSF) is a protease and esterase inhibitor that causes protection or potentiation/promotion of organophosphorus delayed…”
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Roles of NTE protein and encoding gene in development and neurodevelopmental toxicity
Published in Chemico-biological interactions (25-11-2016)“…Neuropathy Target Esterase (NTE) is a membrane protein codified by gene PNPLA6. NTE was initially discovered as a target of the so-called…”
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Esterases hydrolyze phenyl valerate activity as targets of organophosphorus compounds
Published in Chemico-biological interactions (25-11-2016)“…OPs are a large diverse class of chemicals used for several purposes (pesticides, warfare agents, flame retardants, etc.). They can cause several neurotoxic…”
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Neurotoxic Effects Associated with Current Uses of Organophosphorus Compounds
Published in Journal of the Brazilian Chemical Society (01-05-2016)“…Organophosphorus compounds (OPs) are a large and diverse class of chemicals that have been synthesized, since the XIX century for several purposes like…”
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NTE and non-NTE esterases in brain membrane: Kinetic characterization with organophosphates
Published in Toxicology (Amsterdam) (16-07-2012)“…Abstract Some effects of organophosphorus compounds (OPs) esters cannot be explained by action on currently recognized targets. In this work, we evaluate and…”
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Interactions of human butyrylcholinesterase with phenylvalerate and acetylthiocholine as substrates and inhibitors: kinetic and molecular modeling approaches
Published in Archives of toxicology (01-05-2019)“…Phenyl valerate (PV) is a substrate for measuring the PVase activity of neuropathy target esterase (NTE), a key molecular event of organophosphorus-induced…”
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Kinetics of the inhibitory interaction of organophosphorus neuropathy inducers and non-inducers in soluble esterases in the avian nervous system
Published in Toxicology and applied pharmacology (01-11-2011)“…Some published studies suggest that low level exposure to organophosphorus esters (OPs) may cause neurological and neurobehavioral effects at long term…”
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