Search Results - "Essone, Paulin N"
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Epidemiological, Mycobacteriological, and Clinical Characteristics of Smoking Pulmonary Tuberculosis Patients, in Lambaréné, Gabon: A Cross-Sectional Study
Published in The American journal of tropical medicine and hygiene (01-12-2020)“…Gabon carries a high burden of both tuberculosis (TB) and smoking. This study examines the disease characteristics of smoking pulmonary TB patients in…”
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Host cytokine responses induced after overnight stimulation with novel M. tuberculosis infection phase-dependent antigens show promise as diagnostic candidates for TB disease
Published in PloS one (15-07-2014)“…We previously identified Mycobacterium tuberculosis (M.tb) antigen-induced host markers that showed promise as TB diagnostic candidates in 7-day whole blood…”
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Evidence and implications of pre‐existing humoral cross‐reactive immunity to SARS‐CoV‐2
Published in Immunity, Inflammation and Disease (01-03-2021)“…Background Severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) has emerged throughout the world. Building knowledge around Covid‐19 is crucial to…”
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Potential of host markers produced by infection phase-dependent antigen-stimulated cells for the diagnosis of tuberculosis in a highly endemic area
Published in PloS one (05-06-2012)“…Recent interferon gamma (IFN-γ)-based studies have identified novel Mycobacterium tuberculosis (M.tb) infection phase-dependent antigens as diagnostic…”
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Cases of Impaired Oxidative Burst in HIV-Exposed Uninfected Infants' Neutrophils-A Pilot Study
Published in Frontiers in immunology (09-03-2017)“…An increased risk of serious bacterial infections in HIV-exposed uninfected (HEU) infants has been demonstrated. Although neutrophils are essential for the…”
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Potential of novel Mycobacterium tuberculosis infection phase-dependent antigens in the diagnosis of TB disease in a high burden setting
Published in BMC infectious diseases (20-01-2012)“…Confirming tuberculosis (TB) disease in suspects in resource limited settings is challenging and calls for the development of more suitable diagnostic tools…”
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Altered Toll-Like Receptor-4 Response to Lipopolysaccharides in Infants Exposed to HIV-1 and Its Preventive Therapy
Published in Frontiers in immunology (14-02-2018)“…Pathogen sensing and recognition through pattern recognition receptors, and subsequent production of pro-inflammatory cytokines, is the cornerstone of the…”
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Readiness in preventing filovirus epidemics by use of the marketed vaccines against Zaire Ebola virus disease as prototypes
Published in The Lancet infectious diseases (01-07-2024)“…[...]evidence of the safety of the two vaccine regimens holds promise for the safe insertion of non-Zaire Ebola virus filovirus antigens into the vectors…”
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Increased platelets count in HIV-1 uninfected infants born from HIV-1 infected mothers
Published in Hematology reports (27-09-2019)“…HIV-exposed uninfected infants (HEU) represent a growing population in developing countries including Gabon. Several studies have shown the vulnerability of…”
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Performance evaluation of a combination Plasmodium dual-antigen CRP rapid diagnostic test in Lambaréné, Gabon
Published in Infection (23-08-2024)“…The consequent use of malaria rapid diagnostic tests (RDTs) preceding a treatment decision has improved the global management of malaria. A combination RDT,…”
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Correction: Performance evaluation of a combination Plasmodium dual-antigen CRP rapid diagnostic test in Lambaréné, Gabon
Published in Infection (09-10-2024)Get full text
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SARS-CoV-2 infection in Africa: a systematic review and meta-analysis of standardised seroprevalence studies, from January 2020 to December 2021
Published in BMJ global health (01-08-2022)“…IntroductionEstimating COVID-19 cumulative incidence in Africa remains problematic due to challenges in contact tracing, routine surveillance systems and…”
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Dynamic and features of SARS-CoV-2 infection in Gabon
Published in Scientific reports (06-05-2021)“…In a context where SARS-CoV-2 population-wide testing is implemented, clinical features and antibody response in those infected have never been documented in…”
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Creatine kinase-(MB) and hepcidin as candidate biomarkers for early diagnosis of pulmonary tuberculosis: a proof-of-concept study in Lambaréné, Gabon
Published in Infection (01-08-2022)“…Background The present study aimed to evaluate the diagnostic utility of creatine kinase-MB (CK-MB), hepcidin (HEPC), phospholipase A2 group IIA (PLa2G2A), and…”
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Time to SARS‐CoV‐2 clearance in African, Caucasian, and Asian ethnic groups
Published in Influenza and other respiratory viruses (01-06-2024)“…Background COVID‐19 may become a seasonal disease. SARS‐CoV‐2 active circulation coupled with vaccination efforts has undoubtedly modified the virus dynamic…”
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M. tuberculosis infection and antigen specific cytokine response in healthcare workers frequently exposed to tuberculosis
Published in Scientific reports (03-06-2019)“…Tuberculosis (TB) is the leading cause of death due to an infectious agent, but only a small fraction of those infected develop the disease. Cytokines are…”
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Single and Combined Serum Proteins Expressed in TB Infection are Candidates for Point-of-care Diagnostic Testing of Active TB Patients in Lambaréné, Gabon
Published in Open forum infectious diseases (01-08-2024)“…Abstract Background and Objectives Point-of-care testing using nonsputum samples like serum or plasma proteins can improve tuberculosis (TB) patients access to…”
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Publisher Correction: M. tuberculosis infection and antigen specific cytokine response in healthcare workers frequently exposed to tuberculosis
Published in Scientific reports (23-10-2019)“…An amendment to this paper has been published and can be accessed via a link at the top of the paper…”
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Making clinical trials a public norm for health decisions in sub-Saharan Africa
Published in Frontiers in tropical diseases (11-01-2024)Get full text
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Bifunctional T-cell-derived cytokines for the diagnosis of tuberculosis and treatment monitoring
Published in Respiration (01-01-2014)“…Diagnosis and treatment monitoring of patients with tuberculosis remain challenging. We have evaluated whether Mycobacterium-specific interferon (IFN)-γ and…”
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