Search Results - "Esslinger, Hope R."
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Novel computational biology modeling system can accurately forecast response to neoadjuvant therapy in early breast cancer
Published in Breast cancer research : BCR (10-05-2023)“…Generalizable population-based studies are unable to account for individual tumor heterogeneity that contributes to variability in a patient's response to…”
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Morphine clearance in children: does race or genetics matter?
Published in Journal of opioid management (01-07-2012)“…Interindividual variability in analgesic response and adverse effects of opioids because of narrow therapeutic indices are major clinical problems. Morphine is…”
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Race and Unequal Burden of Perioperative Pain and Opioid Related Adverse Effects in Children
Published in Pediatrics (Evanston) (01-05-2012)“…Interindividual variability in pain perception and analgesic response is a major problem in perioperative practice. Adult studies suggest pain management is…”
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OCT1 genetic variants influence the pharmacokinetics of morphine in children
Published in Pharmacogenomics (01-07-2013)“…Large interindividual variability in morphine disposition could contribute to unpredictable variability in morphine analgesia and adverse events. Caucasian…”
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Genetics of pain perception, COMT and postoperative pain management in children
Published in Pharmacogenomics (01-02-2014)“…Effective perioperative analgesia is lacking for children owing to interindividual variations and underdosing of opioids caused by fear of adverse effects. We…”
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Propofol Clearance in Morbidly Obese Children and Adolescents : Influence of Age and Body Size
Published in Clinical pharmacokinetics (01-08-2012)“…Given the alarming increase in obesity among children undergoing surgery, the main aim of this study was to characterize propofol clearance in a cohort of…”
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Codeine-related adverse drug reactions in children following tonsillectomy: A prospective study
Published in The Laryngoscope (01-05-2014)“…Objectives/Hypothesis To prospectively determine factors associated with codeine's adverse drug reactions (ADRs) at home in a large homogenous population of…”
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Propofol Clearance in Morbidly Obese Children and Adolescents: Influence of Age and Body Size
Published in Clinical pharmacokinetics (01-08-2012)“…Background and Objective Given the alarming increase in obesity among children undergoing surgery, the main aim of this study was to characterize propofol…”
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Abstract 749: SimBioSys TumorScope accurately models and predicts response to neoadjuvant therapy in breast cancer - Validation study
Published in Cancer research (Chicago, Ill.) (15-06-2022)“…Neoadjuvant Therapy (NAT) for breast cancer results in higher rates of breast conservation surgery. Importantly, there is data supporting the use of multiple…”
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Propofol Clearance in Morbidly Obese Children and Adolescents
Published in Clinical pharmacokinetics (01-08-2012)“…Background and Objective: Given the alarming increase in obesity among children undergoing surgery, the main aim of this study was to characterize propofol…”
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