Search Results - "Essing, Anke"

Concerted changes in transcripts in the prefrontal cortex precede neuropathology in Alzheimer's disease by Bossers, Koen, Wirz, Kerstin T.S., Meerhoff, Gideon F., Essing, Anke H.W., van Dongen, Jeroen W., Houba, Pieter, Kruse, Chris G., Verhaagen, Joost, Swaab, Dick F.

“…Using the Braak staging for neurofibrillary changes as an objective indicator of the progression of Alzheimer's disease, we have performed a systematic search…”
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Defects in 8-oxo-guanine repair pathway cause high frequency of C > A substitutions in neuroblastoma by van den Boogaard, Marlinde L., Oka, Rurika, Hakkert, Anne, Schild, Linda, Ebus, Marli E., van Gerven, Michael R., Zwijnenburg, Danny A., Molenaar, Piet, Hoyng, Lieke L., Dolman, M. Emmy M., Essing, Anke H. W., Koopmans, Bianca, Helleday, Thomas, Drost, Jarno, van Boxtel, Ruben, Versteeg, Rogier, Koster, Jan, Molenaar, Jan J.

“…Neuroblastomas are childhood tumors with frequent fatal relapses after induction treatment, which is related to tumor evolution with additional genomic events…”
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Gene expression and functional annotation of the human and mouse choroid plexus epithelium by Janssen, Sarah F, van der Spek, Sophie J F, Ten Brink, Jacoline B, Essing, Anke H W, Gorgels, Theo G M F, van der Spek, Peter J, Jansonius, Nomdo M, Bergen, Arthur A B

“…The choroid plexus epithelium (CPE) is a lobed neuro-epithelial structure that forms the outer blood-brain barrier. The CPE protrudes into the brain ventricles…”
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Microarray and morphological analysis of early postnatal CRB2 mutant retinas on a pure C57BL/6J genetic background by Alves, Celso Henrique, Bossers, Koen, Vos, Rogier M, Essing, Anke H W, Swagemakers, Sigrid, van der Spek, Peter J, Verhaagen, Joost, Wijnholds, Jan

“…In humans, the Crumbs homologue-1 (CRB1) gene is mutated in progressive types of autosomal recessive retinitis pigmentosa and Leber congenital amaurosis. The…”
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A new strategy to identify and annotate human RPE-specific gene expression by Booij, Judith C, ten Brink, Jacoline B, Swagemakers, Sigrid M A, Verkerk, Annemieke J M H, Essing, Anke H W, van der Spek, Peter J, Bergen, Arthur A B

“…To identify and functionally annotate cell type-specific gene expression in the human retinal pigment epithelium (RPE), a key tissue involved in age-related…”
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TBX2 is a neuroblastoma core regulatory circuitry component enhancing MYCN/FOXM1 reactivation of DREAM targets by Decaesteker, Bieke, Denecker, Geertrui, Van Neste, Christophe, Dolman, Emmy M., Van Loocke, Wouter, Gartlgruber, Moritz, Nunes, Carolina, De Vloed, Fanny, Depuydt, Pauline, Verboom, Karen, Rombaut, Dries, Loontiens, Siebe, De Wyn, Jolien, Kholosy, Waleed M., Koopmans, Bianca, Essing, Anke H. W., Herrmann, Carl, Dreidax, Daniel, Durinck, Kaat, Deforce, Dieter, Van Nieuwerburgh, Filip, Henssen, Anton, Versteeg, Rogier, Boeva, Valentina, Schleiermacher, Gudrun, van Nes, Johan, Mestdagh, Pieter, Vanhauwaert, Suzanne, Schulte, Johannes H., Westermann, Frank, Molenaar, Jan J., De Preter, Katleen, Speleman, Frank

“…Chromosome 17q gains are almost invariably present in high-risk neuroblastoma cases. Here, we perform an integrative epigenomics search for dosage-sensitive…”
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Gene expression and functional annotation of the human ciliary body epithelia by Janssen, Sarah F, Gorgels, Theo G M F, Bossers, Koen, Ten Brink, Jacoline B, Essing, Anke H W, Nagtegaal, Martijn, van der Spek, Peter J, Jansonius, Nomdo M, Bergen, Arthur A B

“…The ciliary body (CB) of the human eye consists of the non-pigmented (NPE) and pigmented (PE) neuro-epithelia. We investigated the gene expression of NPE and…”
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Epigenetic modulation of neuroblastoma enhances T cell and NK cell immunogenicity by inducing a tumor-cell lineage switch by Cornel, Annelisa M, Dunnebach, Ester, Hofman, Damon A, Das, Sanjukta, Sengupta, Satyaki, van den Ham, Femke, Wienke, Judith, Strijker, Josephine G M, van den Beemt, Denise A M H, Essing, Anke H W, Koopmans, Bianca, Engels, Sem A G, Lo Presti, Vania, Szanto, Celina S, George, Rani E, Molenaar, Jan J, van Heesch, Sebastiaan, Dierselhuis, Miranda P, Nierkens, S

“…BackgroundImmunotherapy in high-risk neuroblastoma (HR-NBL) does not live up to its full potential due to inadequate (adaptive) immune engagement caused by the…”
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Functional annotation of the human retinal pigment epithelium transcriptome by Booij, Judith C, van Soest, Simone, Swagemakers, Sigrid M A, Essing, Anke H W, Verkerk, Annemieke J M H, van der Spek, Peter J, Gorgels, Theo G M F, Bergen, Arthur A B

“…To determine level, variability and functional annotation of gene expression of the human retinal pigment epithelium (RPE), the key tissue involved in retinal…”
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A multilevel screening strategy defines a molecular fingerprint of proregenerative olfactory ensheathing cells and identifies SCARB2, a protein that improves regenerative sprouting of injured sensory spinal axons by Roet, Kasper C D, Franssen, Elske H P, de Bree, Frederik M, Essing, Anke H W, Zijlstra, Sjirk-Jan J, Fagoe, Nitish D, Eggink, Hannah M, Eggers, Ruben, Smit, August B, van Kesteren, Ronald E, Verhaagen, Joost

“…Olfactory ensheathing cells (OECs) have neuro-restorative properties in animal models for spinal cord injury, stroke, and amyotrophic lateral sclerosis. Here…”
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Decitabine mildly attenuates MLL‐rearranged acute lymphoblastic leukemia in vivo, and represents a poor chemo‐sensitizer by Schneider, Pauline, Castro, Patricia Garrido, Pinhanços, Sandra M., Kerstjens, Mark, Roon, Eddy H., Essing, Anke H.W., Dolman, M. Emmy M., Molenaar, Jan J., Pieters, Rob, Stam, Ronald W.

“…MLL‐rearranged acute lymphoblastic leukemia (ALL) represents a highly aggressive ALL subtype, characterized by aberrant DNA methylation patterns. DNA…”
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The potential of PARP as a therapeutic target across pediatric solid malignancies by Keller, Kaylee M, Koetsier, Joost, Schild, Linda, Amo-Addae, Vicky, Eising, Selma, van den Handel, Kim, Ober, Kimberley, Koopmans, Bianca, Essing, Anke, van den Boogaard, Marlinde L, Langenberg, Karin P S, Jäger, Natalie, Kool, Marcel, Pfister, Stefan, Dolman, M Emmy M, Molenaar, Jan J, van Hooff, Sander R

“…Pediatric cancer is the leading cause of disease-related death in children and the need for better therapeutic options remains urgent. Due to the limited…”
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Comparative gene expression profiling of olfactory ensheathing glia and Schwann cells indicates distinct tissue repair characteristics of olfactory ensheathing glia by Franssen, Elske H.P., De Bree, Freddy M., Essing, Anke H.W., Ramon-Cueto, Almudena, Verhaagen, Joost

“…Olfactory ensheathing glia (OEG) are a specialized type of glia that support the growth of primary olfactory axons from the neuroepithelium in the nasal cavity…”
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Comparison of human retinal pigment epithelium gene expression in macula and periphery highlights potential topographic differences in Bruch's membrane by van Soest, Simone S, de Wit, Gerard M J, Essing, Anke H W, ten Brink, Jacoline B, Kamphuis, Willem, de Jong, Paulus T V M, Bergen, Arthur A B

“…To describe gene expression differences between healthy, young human retinal pigment epithelium (RPE) cells from the macular area and RPE cells from two…”
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Abstract 2630: Preclinical identification of Venetoclax combination strategies with Idasanutlin, CUDC-907, Prexasertib or Talazoparib for neuroblastoma treatment by Dolman, M. Emmy M., Bate-Eya, Laurel T., Vernooij, Lindy, Koopmans, Bianca, Alles, Lindy K., Essing, Anke H., Lelieveld, Daphne, Egan, David A., Kerstjens, Mark, Stam, Ronald W., Caron, Huib N., Molenaar, Jan J.

“…BACKGROUND: The anti-apoptotic protein B cell lymphoma/leukaemia 2 (BCL-2) is highly expressed in the majority of all neuroblastomas. In previous preclinical…”
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Microarray and Morphological Analysis of Early Postnatal CRB2 Mutant Retinas on a Pure C57BL/6J Genetic Background: e82532 by Alves, Celso Henrique, Bossers, Koen, Vos, Rogier M, Essing, Anke HW, Swagemakers, Sigrid, Spek, J vander, Verhaagen, Joost, Wijnholds, Jan

“…In humans, the Crumbs homologue-1 (CRB1) gene is mutated in progressive types of autosomal recessive retinitis pigmentosa and Leber congenital amaurosis. The…”
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Gene Expression and Functional Annotation of the Human and Mouse Choroid Plexus Epithelium: e83345 by Janssen, Sarah F, Spek, F vander, Brink, Jacoline Bten, Essing, Anke HW, Gorgels, G MF, Spek, J vander, Jansonius, Nomdo M, Bergen, Arthur AB

“…Background The choroid plexus epithelium (CPE) is a lobed neuro-epithelial structure that forms the outer blood-brain barrier. The CPE protrudes into the brain…”
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