Search Results - "Essam, Reham M"

Therapeutic effects of combining curcumin and swimming in osteoarthritis using a rat model by Saber, Mona M., Mahmoud, Manal Moustafa, Amin, Hesham M., Essam, Reham M.

“…Osteoarthritis (OA) is a common debilitating degenerative disease of the elderly. We aimed to study the therapeutic effects of combining curcumin and swimming…”
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The citrus flavonoid “Nobiletin” impedes STZ-induced Alzheimer’s disease in a mouse model through regulating autophagy mastered by SIRT1/FoxO3a mechanism by El-Maraghy, Shohda A., Reda, Aya, Essam, Reham M., Kortam, Mona A.

“…The prominence of autophagy in the modulation of neurodegenerative disorders has sparked interest to investigate its stimulation in Alzheimer's disease (AD)…”
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A Comparative Study of the Antihypertensive and Cardioprotective Potentials of Hot and Cold Aqueous Extracts of Hibiscus sabdariffa L. in Relation to Their Metabolic Profiles by Salem, Mohamed A, Ezzat, Shahira M, Ahmed, Kawkab A, Alseekh, Saleh, Fernie, Alisdair R, Essam, Reham M

“…Since ancient times, L. calyces have been used as a folk remedy for the treatment of hypertension. However, it is questionable as to whether there is a…”
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p-CREB and p-DARPP-32 orchestrating the modulatory role of cAMP/PKA signaling pathway enhanced by Roflumilast in rotenone-induced Parkinson's disease in rats by Essam, Reham M., Kandil, Esraa A.

“…Recently, phosphodiesterases (PDEs) have gained great attention due to their implication in Parkinson's disease (PD) pathogenesis. Noteworthy, the PDE4 enzyme…”
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Lactoferrin averts neurological and behavioral impairments of thioacetamide-induced hepatic encephalopathy in rats via modulating HGMB1/TLR-4/MyD88/Nrf2 pathway by Essam, Reham M., Saadawy, Mariam A., Gamal, Mahitab, Abdelsalam, Rania M., El-Sahar, Ayman E.

“…Hepatic encephalopathy (HE) is a life-threatening disease caused by acute or chronic liver failure manifested by aberrant CNS changes. In the present study, we…”
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Phosphodiestrase-1 and 4 inhibitors ameliorate liver fibrosis in rats: Modulation of cAMP/CREB/TLR4 inflammatory and fibrogenic pathways by Essam, Reham M., Ahmed, Lamiaa A., Abdelsalam, Rania M., El-Khatib, Aiman S.

“…Phosphodiestrase (PDE) enzymes are suggested to play a leading role in fibrogenesis of liver where studies showed the possible implication of PDE 1 & 4 in…”
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Donepezil halts acetic acid-induced experimental colitis in rats and its associated cognitive impairment through regulating inflammatory/oxidative/apoptotic cascades: An add-on to its anti-dementia activity by Elbaz, Eman M., Essam, Reham M., Ahmed, Kawkab A., Safwat, Maheera H.

“…[Display omitted] •The study reported the protective effect of DON against acetic acid-induced colitis in rats.•Our work also demonstrated that DON guards…”
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Targeting HMGB1/PI3K/Akt and NF-κB/Nrf-2 signaling pathways by vildagliptin mitigates testosterone-induced benign prostate hyperplasia in rats by El-Sahar, Ayman E., Bekhit, Nadine, Eissa, Noha M., Abdelsalam, Rania M., Essam, Reham M.

“…Benign prostatic hyperplasia (BPH) is a prevalent illness in older adults. It is well-recognized that testosterone is essential in the onset of BPH…”
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Empagliflozin Dampens Doxorubicin-Induced Chemobrain in Rats: The Possible Involvement of Oxidative Stress and PI3K/Akt/mTOR/NF-κB/TNF-α Signaling Pathways by Abdelsalam, Rania M, Hamam, Hatem W, Eissa, Noha M, El-Sahar, Ayman E, Essam, Reham M

“…Chemobrain is a cognitive impairment observed in up to 75% of cancer patients treated with doxorubicin (DOX). Cognitive deficits associated with DOX are…”
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Implication of Wnt/GSK-3β/β-Catenin Signaling in the Pathogenesis of Mood Disturbances Associated with Hyperthyroidism in Rats: Potential Therapeutic Effect of Naringin by Abd-Elmawla, Mai A., Essam, Reham M., Ahmed, Kawkab A., Abdelmonem, Maha

“…Patients with hyperthyroidism are commonly diagnosed with mood disorders. Naringin, (4′,5,7-trihydrocyflavanone-7-O-rhamnoglucoside), a natural bioflavonoid,…”
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The Interplay between MiR-134/BDNF and LKB1/AMPK/SIRT1 Accentuates the Antidepressant Efficacy of Empagliflozin in Ovariectomized Rats by Fathy, Nevine, Labib, Merna A., Essam, Reham M., El-Boghdady, Noha A.

“…Major depressive disorder (MDD) is considered a major cause of suicide worldwide. As previous studies revealed that neuroinflammation is a significant factor…”
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The preferential effect of Clemastine on F3/Contactin-1/Notch-1 compared to Jagged-1/Notch-1 justifies its remyelinating effect in an experimental model of multiple sclerosis in rats by Ibrahim, Sherehan M., Kamel, Ahmed S., Ahmed, Kawkab A., Mohammed, Reham A., Essam, Reham M.

“…[Display omitted] •Jagged-1/Notch-1 is activated in experimental autoimmune encephalomyelitis (EAE).•Clemastine enhanced MBP and Oligo2 in corpus…”
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Novel fast dissolving freeze dried sublingual baicalin tablets for enhanced hepatoprotective effect: in-vitro characterization, cell viability, and in-vivo evaluation by Abdelrazek, Farida N, Shalaby, Rodayna A, Fahim, Sally A, Essam, Reham M, Anis, Shady E, Attia, Yasmin M, Abd El Malak, Nevine S

“…Baicalin (BG), a natural product, has been used in the prevention and treatment of drug-induced liver injury (DILI); however, its poor solubility and extensive…”
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Lutein exerts its cardioprotective effect against the experimental model of isoprenaline‐induced myocardial infarction via MIAT/miR‐200a/Nrf2/TXINP pathway by Abdelmonem, Maha, Ibrahim, Sherehan M., Essam, Reham M., Amin, Hebat Allah A., Abd‐Elmawla, Mai A.

“…Acute myocardial infarction (AMI) remains a leading cause of morbidity and mortality worldwide. Lutein (LU) possesses numerous pharmacological activities,…”
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IRats:Intelligent system for rat behavior analysis by Zaky, Andrew, Saber, Mona M, Essam, Reham M., Atia, Ayman

“…Rats' behavior analysis is fundamentally important in the medical field and pharmaceutical industry. Drugs and chemical compounds are given to mice and rats to…”
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Mycosis fungoides bullosa: An unusual presentation of a rare entity by Nofal, Ahmad, Alakad, Rania, Ehab, Rana, Essam, Reham

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