Search Results - "Esposito, Mark"

Targeting tumor―stromal interactions in bone metastasis by ESPOSITO, Mark, YIBIN KANG

“…Bone metastasis is a frequent occurrence in late stage solid tumors, including breast cancers, prostate or lung. However, the causes for this proclivity have…”
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Reversal of Cytosolic One-Carbon Flux Compensates for Loss of the Mitochondrial Folate Pathway by Ducker, Gregory S., Chen, Li, Morscher, Raphael J., Ghergurovich, Jonathan M., Esposito, Mark, Teng, Xin, Kang, Yibin, Rabinowitz, Joshua D.

“…One-carbon (1C) units for purine and thymidine synthesis can be generated from serine by cytosolic or mitochondrial folate metabolism. The mitochondrial 1C…”
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Genetic and pharmacologic inhibition of ALDH1A3 as a treatment of β-cell failure by Son, Jinsook, Du, Wen, Esposito, Mark, Shariati, Kaavian, Ding, Hongxu, Kang, Yibin, Accili, Domenico

“…Type 2 diabetes (T2D) is associated with β-cell dedifferentiation. Aldehyde dehydrogenase 1 isoform A3 (ALHD1A3) is a marker of β-cell dedifferentiation and…”
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Tinagl1 Suppresses Triple-Negative Breast Cancer Progression and Metastasis by Simultaneously Inhibiting Integrin/FAK and EGFR Signaling by Shen, Minhong, Jiang, Yi-Zhou, Wei, Yong, Ell, Brian, Sheng, Xinlei, Esposito, Mark, Kang, Jooeun, Hang, Xiang, Zheng, Hanqiu, Rowicki, Michelle, Zhang, Lanjing, Shih, Weichung J., Celià-Terrassa, Toni, Liu, Yirong, Cristea, IIeana, Shao, Zhi-Ming, Kang, Yibin

“…Triple-negative breast cancer (TNBC) patients have the worst prognosis and distant metastasis-free survival among all major subtypes of breast cancer. The poor…”
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The role of PFC networks in cognitive control and executive function by Menon, Vinod, D'Esposito, Mark

“…Systems neuroscience approaches with a focus on large-scale brain organization and network analysis are advancing foundational knowledge of how cognitive…”
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From cognitive to neural models of working memory by Mark D'Esposito

“…Working memory refers to the temporary retention of information that was just experienced or just retrieved from long-term memory but no longer exists in the…”
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Bisphosphoglycerate mutase controls serine pathway flux via 3-phosphoglycerate by Oslund, Rob C, Su, Xiaoyang, Haugbro, Michael, Kee, Jung-Min, Esposito, Mark, David, Yael, Wang, Boyuan, Ge, Eva, Perlman, David H, Kang, Yibin, Muir, Tom W, Rabinowitz, Joshua D

“…Bisphosphoglycerate mutase (BPGM) drives phosphoglycerate mutase 1 (PGAM1) phosphorylation, which is required for glycolytic flux. Loss of BPGM is partially…”
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Cytotoxic alkyl-quinolones mediate surface-induced virulence in Pseudomonas aeruginosa by Vrla, Geoffrey D, Esposito, Mark, Zhang, Chen, Kang, Yibin, Seyedsayamdost, Mohammad R, Gitai, Zemer, Hauser, Alan R, Wolfgang, Matthew C

“…Surface attachment, an early step in the colonization of multiple host environments, activates the virulence of the human pathogen P. aeruginosa. However, the…”
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The Cognitive Neuroscience of Working Memory by D'Esposito, Mark, Postle, Bradley R

“…For more than 50 years, psychologists and neuroscientists have recognized the importance of a working memory to coordinate processing when multiple goals are…”
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The Segregation and Integration of Distinct Brain Networks and Their Relationship to Cognition by Cohen, Jessica R, D'Esposito, Mark

“…A critical feature of the human brain that gives rise to complex cognition is its ability to reconfigure its network structure dynamically and adaptively in…”
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Are individual differences in human brain organization measured with functional MRI meaningful? by D’Esposito, Mark

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Is the rostro-caudal axis of the frontal lobe hierarchical? by Badre, David, D'Esposito, Mark

“…Key Points Recent studies have reported rostro-caudal distinctions in frontal cortex activity based on the level of abstractness of action representations…”
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Brain Modularity: A Biomarker of Intervention-related Plasticity by Gallen, Courtney L., D’Esposito, Mark

“…Interventions using methods such as cognitive training and aerobic exercise have shown potential to enhance cognitive abilities. However, there is often…”
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Verb Generation in Patients with Focal Frontal Lesions: A Neuropsychological Test of Neuroimaging Findings by Thompson-Schill, Sharon L., Swick, Diane, Farah, Martha J., D'Esposito, Mark, Kan, Irene P., Knight, Robert T.

“…What are the neural bases of semantic memory? Traditional beliefs that the temporal lobes subserve the retrieval of semantic knowledge, arising from lesion…”
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The what, where and how of delay activity by Sreenivasan, Kartik K., D’Esposito, Mark

“…Working memory is characterized by neural activity that persists during the retention interval of delay tasks. Despite the ubiquity of this delay activity…”
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The Neural Substrate and Temporal Dynamics of Interference Effects in Working Memory as Revealed by Event-Related Functional MRI by D'Esposito, Mark, Postle, Bradley R., Jonides, John, Smith, Edward E.

“…Research on the prefrontal cortex (PFC) of monkeys and humans indicates that this region supports a heterogeneous repertoire of mental processes that…”
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Functional Characterization of the Cingulo-Opercular Network in the Maintenance of Tonic Alertness by Sadaghiani, Sepideh, D'Esposito, Mark

“…The complex processing architecture underlying attentional control requires delineation of the functional role of different control-related brain networks. A…”
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The Human Thalamus Is an Integrative Hub for Functional Brain Networks by Hwang, Kai, Bertolero, Maxwell A, Liu, William B, D'Esposito, Mark

“…The thalamus is globally connected with distributed cortical regions, yet the functional significance of this extensive thalamocortical connectivity remains…”
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Causal Contribution of Awake Post-encoding Processes to Episodic Memory Consolidation by Tambini, Arielle, D’Esposito, Mark

“…Stable representations of past experience are thought to depend on processes that unfold after events are initially encoded into memory. Post-encoding…”
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The neural basis of the central executive system of working memory by D'Esposito, Mark, Detre, John A, Alsop, David C, Shin, Robert K, Atlas, Scott, Grossman, Murray

“…Working memory refers to a system for temporary storage and manipulation of information in the brain, a function critical for a wide range of cognitive…”
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