Search Results - "Esposito, Maria Teresa"

Thirty years of SET/TAF1β/I2PP2A: from the identification of the biological functions to its implications in cancer and Alzheimer’s disease by Di Mambro, Antonella, Esposito, Maria Teresa

“…Abstract The gene encoding for the protein SE translocation (SET) was identified for the first time 30 years ago as part of a chromosomal translocation in a…”
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Synthetic lethal targeting of oncogenic transcription factors in acute leukemia by PARP inhibitors by Esposito, Maria Teresa, Zhao, Lu, Fung, Tsz Kan, Rane, Jayant K, Wilson, Amanda, Martin, Nadine, Gil, Jesus, Leung, Anskar Y, Ashworth, Alan, Eric So, Chi Wai

“…The authors uncover a therapeutic vulnerability to PARP inhibition of acute myeloid leukemias driven by certain oncogenic fusions, and they unravel the…”
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Hematopoietic stem cells meet induced pluripotent stem cells technology by Esposito, Maria Teresa

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The Impact of PI3‐kinase/RAS Pathway Cooperating Mutations in the Evolution of KMT2A‐rearranged Leukemia by Esposito, Maria Teresa

“…Supplemental Digital Content is available in the text Leukemia is an evolutionary disease and evolves by the accrual of mutations within a clone. Those…”
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Editorial: Chemosensitizing effect of natural products against cancers: Applications in enhancing chemotherapy and immunotherapy by Roy, Nand K., Tewari, Devesh, Esposito, Maria Teresa

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Editorial: Harnessing chemotherapy resistance and development of novel therapeutic strategies for acute leukemia with KMT2A (MLL)-gene rearrangements by Esposito, Maria Teresa, Hagström-Andersson, Anna, Stam, Ronald W., Bortoluzzi, Stefania

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A Placental Growth Factor Variant Unable to Recognize Vascular Endothelial Growth Factor (VEGF) Receptor-1 Inhibits VEGF-Dependent Tumor Angiogenesis via Heterodimerization by TARALLO, Valeria, VESCI, Loredana, CAPASSO, Onofrio, ESPOSITO, Maria Teresa, RICCIONI, Teresa, PASTORE, Lucio, ORLANDI, Augusto, PISANO, Claudio, DE FALCO, Sandro

“…Angiogenesis is one of the crucial events for cancer development and growth. Two members of the vascular endothelial growth factor (VEGF) family, VEGF-A and…”
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Culture conditions allow selection of different mesenchymal progenitors from adult mouse bone marrow by Esposito, Maria Teresa, Di Noto, Rosa, Mirabelli, Peppino, Gorrese, Marisa, Parisi, Silvia, Montanaro, Donatella, Del Vecchio, Luigi, Pastore, Lucio

“…The use of adult stem cells in tissue engineering approaches will benefit from the establishment of culture conditions that allow the expansion and maintenance…”
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905-P: Simulation Model Estimating Lifetime Health and Economic Outcomes of Prediabetes Screening by One-Hour Plasma Glucose by ANDELLINI, MARTINA, MANCO, MELANIA, ESPOSITO, MARIA TERESA, TOZZI, ALBERTO EUGENIO, BERGMAN, MICHAEL, RITROVATO, MATTEO

“…Background: One of the current methods to diagnose prediabetes and predict diabetes incidence is based on 2-h plasma glucose (2-hPG) value following 75-g oral…”
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β-Catenin Mediates the Establishment and Drug Resistance of MLL Leukemic Stem Cells by Yeung, Jenny, Esposito, Maria Teresa, Gandillet, Arnaud, Zeisig, Bernd B., Griessinger, Emmanuel, Bonnet, Dominique, So, Chi Wai Eric

“…Identification of molecular pathways essential for cancer stem cells is critical for understanding the underlying biology and designing effective cancer…”
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Blood factory: which stem cells? by Esposito, Maria Teresa

“…Blood transfusions are often essential for treatment of severe anaemia and pregnancy complications. The unavailability of blood is a medical concern,…”
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DNA damage accumulation and repair defects in acute myeloid leukemia: implications for pathogenesis, disease progression, and chemotherapy resistance by Esposito, Maria Teresa, So, Chi Wai Eric

“…DNA damage repair mechanisms are vital to maintain genomic integrity. Mutations in genes involved in the DNA damage response (DDR) can increase the risk of…”
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A simulation model estimates lifetime health and economic outcomes of screening prediabetes using the 1-h plasma glucose by Andellini, Martina, Manco, Melania, Esposito, Maria Teresa, Tozzi, Alberto Eugenio, Bergman, Michael, Ritrovato, Matteo

“…Aims The current method to diagnose impaired glucose tolerance (IGT) is based on the 2-h plasma glucose (2-hPG) value during a 75-g oral glucose tolerance test…”
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Downstream process and evaluation of the concomitant impact of a recombinant glycosylated L-asparaginase on leukemic cancer cells and the bone marrow tumor microenvironment by Kleingesinds, Eduardo Krebs, de Almeida Parizotto, Letícia, Effer, Brian, Monteiro, Gisele, Long, Paul F., Arroyo-Berdugo, Yoana, Behrends, Volker, Esposito, Maria Teresa, Calle, Yolanda, Pessoa-Jr, Adalberto

“…L-asparaginase (L-ASNase) is a life-saving medication used in the treatment of Acute Lymphoblastic Leukemia (ALL) which affects over 60,000 people yearly…”
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Cerrado and Pantanal fruit flours affect gut microbiota composition in healthy and post‐COVID‐19 individuals: an in vitro pilot fermentation study by Mauro, Carolina Saori Ishii, Hassani, Maryame Kadiri, Barone, Monica, Esposito, Maria Teresa, Calle, Yolanda, Behrends, Volker, Garcia, Sandra, Brigidi, Patrizia, Turroni, Silvia, Costabile, Adele

“…Summary Cerrado and Pantanal plants can provide fruits with high nutritional value and antioxidants. This study aims to evaluate four fruit flours (from jatobá…”
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SET-PP2A complex as a new therapeutic target in KMT2A (MLL) rearranged AML by Di Mambro, Antonella, Arroyo-Berdugo, Yoana, Fioretti, Tiziana, Randles, Michael, Cozzuto, Luca, Rajeeve, Vinothini, Cevenini, Armando, Austin, Michael J., Esposito, Gabriella, Ponomarenko, Julia, Lucas, Claire M., Cutillas, Pedro, Gribben, John, Williams, Owen, Calle, Yolanda, Patel, Bela, Esposito, Maria Teresa

“…KMT2A -rearranged (KMT2A-R) is an aggressive and chemo-refractory acute leukemia which mostly affects children. Transcriptomics-based characterization and…”
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Angiotensin receptor I stimulates osteoprogenitor proliferation through TGFβ-mediated signaling by Querques, Francesca, Cantilena, Bruno, Cozzolino, Carmine, Esposito, Maria Teresa, Passaro, Fabiana, Parisi, Silvia, Lombardo, Barbara, Russo, Tommaso, Pastore, Lucio

“…Clinical studies of large human populations and pharmacological interventions in rodent models have recently suggested that anti‐hypertensive drugs that target…”
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Angiotensin receptor I stimulates osteoprogenitor proliferation through TGF[beta]-mediated signaling by Querques, Francesca, Cantilena, Bruno, Cozzolino, Carmine, Esposito, Maria Teresa, Passaro, Fabiana, Parisi, Silvia, Lombardo, Barbara, Russo, Tommaso, Pastore, Lucio

“…Clinical studies of large human populations and pharmacological interventions in rodent models have recently suggested that anti-hypertensive drugs that target…”
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Angiotensin receptor I stimulates osteoprogenitor proliferation through TGFβ-mediated signaling: AT1R SIGNALING IN OSTEOBLAST DIFFERENTIATION by Querques, Francesca, Cantilena, Bruno, Cozzolino, Carmine, Esposito, Maria Teresa, Passaro, Fabiana, Parisi, Silvia, Lombardo, Barbara, Russo, Tommaso, Pastore, Lucio

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Abstract LB-370: A placental growth factor variant unable to recognize VEGFR-1 inhibits VEGF-dependent tumor angiogenesis via heterodimerization by De Falco, Sandro, Tarallo, Valeria, Capasso, Onofrio, Vesci, Loredana, Esposito, Maria Teresa, Pastore, Lucio, Orlandi, Augusto, Pisano, Claudio

“…Abstract Angiogenesis is one of the crucial events for cancer development and growth. Two members of vascular endothelial growth factor (VEGF) family, VEGF-A…”
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