Search Results - "Espitia Pinzón, Clara"
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Synthesis and antituberculosis activity of new acylthiosemicarbazides designed by structural modification
Published in Drug development research (01-05-2020)“…Acylthiosemicarbazides 8a–n were designed by structural modification of lead Compound 7. The syntheses of 8a–n involve a five‐step procedure starting from…”
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2
Differential mast cell numbers and characteristics in human tuberculosis pulmonary lesions
Published in Scientific reports (21-05-2021)“…Tuberculosis (TB) is still a major worldwide health threat and primarily a lung disease. The innate immune response against Mycobacterium tuberculosis ( Mtb )…”
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3
Antinociceptive, anti‐inflammatory, and central nervous system (CNS) effects of the natural coumarin soulattrolide
Published in Drug development research (01-11-2018)“…Soulattrolide is a natural coumarin synthesized by the leaves of species of Calophyllum (Calophyllaceae) rain forest trees, including the American C…”
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4
Synthesis and antitubercular activity of new N -[5-(4-chlorophenyl)-1,3,4-oxadiazol-2-yl]-(nitroheteroaryl)carboxamides
Published in Heterocyclic communications (19-04-2019)“…Nitro-substituted heteroaromatic carboxamides 1a-e were synthesized and tested against three Mycobacterium tuberculosis cell lines. The activities can be…”
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5
The protective effect of immunoglobulin in murine tuberculosis is dependent on IgG glycosylation
Published in Pathogens and disease (01-12-2013)“…Abstract Antibodies have demonstrated having a protective effect in animal models of tuberculosis (TB). These experiments have considered the specificity of…”
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6
Natural Compounds from Mexican Medicinal Plants as Potential Drug Leads for Anti-Tuberculosis Drugs
Published in Anais da Academia Brasileira de Ciências (2017)“…In Mexican Traditional Medicine 187 plant species are used in the treatment of respiratory conditions that may be associated with tuberculosis. In this…”
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Antimycobacterial and HIV-1 Reverse Transcriptase Activity of Julianaceae and Clusiaceae Plant Species from Mexico
Published in Evidence-based complementary and alternative medicine (01-01-2015)“…The extracts of 14 Julianaceae and 5 Clusiaceae species growing in Mexico were tested in vitro (50 µg/mL) against Mycobacterium tuberculosis H37Rv and HIV…”
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Antimycobacterial Activity of Alkaloids and Extracts from Tabernaemontana alba and T. arborea
Published in Planta medica (01-01-2022)“…Tuberculosis is the main cause of death from a single infectious agent. Globally, according to the World Health Organization, in 2018, there were an estimated…”
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Trypanocidal and toxicological assessment in vitro and in silico of three sesquiterpene lactones from Asteraceae plant species
Published in Food and chemical toxicology (01-03-2019)“…We report the effect of the Sesquiterpene Lactones Ambrosin, Incomptine B and Glaucolide E against seven strains of Trypanosoma cruzi, the etiological agent of…”
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10
Characterization of excretory/secretory products of the Taenia crassiceps cysticercus involved in the induction of regulatory T cells in vivo
Published in Parasitology research (1987) (01-07-2023)“…The ability to modulate the host immune response has allowed some parasites to establish themselves in the tissues of an immunocompetent organism. While some…”
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Synthesis and anti-tuberculosis activity of the marine natural product caulerpin and its analogues
Published in Marine drugs (27-03-2014)“…Caulerpin (1a), a bis-indole alkaloid from the marine algal Caulerpa sp., was synthesized in three reaction steps with an overall yield of 11%. The caulerpin…”
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12
Antimycobacterial activity of an anthracycline produced by an endophyte isolated from Amphipterygium adstringens
Published in Molecular biology reports (01-12-2018)“…The search for new compounds effective against Mycobacterium tuberculosis is still a priority in medicine. The evaluation of microorganisms isolated from…”
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13
Antibacterial, Antidiabetic, and Toxicity Effects of Two Brown Algae: Sargassum buxifolium and Padina gymnospora
Published in International Journal of Plant Biology (30-12-2022)“…Seaweed has a variety or biological activities, including antibacterial, antioxidant, antidiabetic, and anti-inflammatory ones. Mexico has great macroalgae…”
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14
Optimization of rifampicin encapsulation in PLGA polymeric reservoirs
Published in International journal of pharmaceutics (25-06-2022)“…[Display omitted] Rifampicin is one of the most commonly used antibiotics for treating tuberculosis, but shows low bioavailability and requires long-term…”
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15
New Isoflavonoids from the extract of Rhynchosia precatoria (Humb. & Bonpl. ex Willd.) DC. and their antimycobacterial activity
Published in Journal of ethnopharmacology (12-07-2017)“…The evaluation of the antimycobacterial activity of extracts of medicinal plants used by Mayos against tuberculosis and respiratory problems, allowed the…”
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16
A significant therapeutic effect of immunoglobulins administered alone, or in combination with conventional chemotherapy, in experimental pulmonary tuberculosis caused by drug-sensitive or drug-resistant strains
Published in Pathogens and disease (29-12-2017)“…The recommended chemotherapy for drug-sensitive tuberculosis (TB) consists of four different antibiotics administrated for 6 months. This long treatment leads…”
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Autoantibodies to Interferon-γ in a Patient with Selective Susceptibility to Mycobacterial Infection and Organ-Specific Autoimmunity
Published in Clinical infectious diseases (01-01-2004)“…We evaluated a patient with disseminated Mycobacterium tuberculosis and Mycobacterium chelonae infection, of which he died. He also developed autoimmune (type…”
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18
Antibody responses to influenza viruses in paediatric patients and their contacts at the onset of the 2009 pandemic in Mexico
Published in Journal of infection in developing countries (15-03-2015)“…On April 2009, the Mexican Ministry of Health received notification of cases of severe pneumonia mostly affecting young healthy people; this was the beginning…”
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Nanoanticuerpos: desarrollo biotecnológico y aplicaciones
Published in TIP. Revista especializada en ciencias químico-biológicas (15-12-2021)“…Los anticuerpos monoclonales son una de las herramientas más revolucionarias en el área de la biomedicina por tener aplicaciones inmunoterapéuticas e…”
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A new vaccine against tuberculosis shows greater protection in a mouse model with progressive pulmonary tuberculosis
Published in Tuberculosis (Edinburgh, Scotland) (01-01-2005)“…Setting: The effectiveness of Bacillus Calmette-Guerin (BCG) vaccination in reducing tuberculosis (TB) prevalence rates is poor, resulting in urgent need for…”
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