Search Results - "Espinoza‐Sanchez, Nancy Adriana"
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Evidence of lateral transmission of aggressive features between different types of breast cancer cells
Published in International journal of oncology (01-11-2017)“…Breast cancer (BrC) is a major public health problem worldwide. The intra-tumoral heterogeneity and tumor cell plasticity importantly contribute to disease…”
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Monocyte Differentiation towards Protumor Activity Does Not Correlate with M1 or M2 Phenotypes
Published in Journal of immunology research (01-01-2016)“…Macrophages facilitate breast cancer progression. Macrophages were initially classified as M1 or M2 based on their distinct metabolic programs and then…”
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SETD3 acts as a prognostic marker in breast cancer patients and modulates the viability and invasion of breast cancer cells
Published in Scientific reports (10-02-2020)“…In several carcinomas, the SET Domain Containing 3, Actin Histidine Methyltransferase (SETD3) is associated with oncogenesis. However, there is little…”
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Prognostic significance of hedgehog signaling network‐related gene expression in breast cancer patients
Published in Journal of cellular biochemistry (01-05-2021)“…Breast cancer continues to be a serious public health problem. The role of the hedgehog pathway in normal development of the mammary gland as well as in…”
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The heparan sulphate proteoglycan Syndecan‐1 (CD138) regulates tumour progression in a 3D model of ductal carcinoma in situ of the breast
Published in IUBMB life (01-10-2022)“…Ductal carcinoma in situ (DCIS) is a form of breast cancer that is restricted to the lactiferous ducts and has not yet invaded the surrounding breast tissue…”
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Syndecan-1 Depletion Has a Differential Impact on Hyaluronic Acid Metabolism and Tumor Cell Behavior in Luminal and Triple-Negative Breast Cancer Cells
Published in International journal of molecular sciences (30-05-2021)“…Glycosaminoglycans (GAGs) and proteoglycans (PGs) are major components of the glycocalyx. The secreted GAG and CD44 ligand hyaluronic acid (HA), and the cell…”
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microRNA‐140‐3p modulates invasiveness, motility, and extracellular matrix adhesion of breast cancer cells by targeting syndecan‐4
Published in Journal of cellular biochemistry (01-10-2021)“…Syndecan‐4, a predicted target of the microRNA miR‐140‐3p, plays an important role in multiple steps of tumor progression and is the second most abundant…”
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Antioxidants Hydroxytyrosol and Thioredoxin-Mimetic Peptide CB3 Protect Irradiated Normal Tissue Cells
Published in Antioxidants (07-08-2024)“…Reducing side effects in non-cancerous tissue is a key aim of modern radiotherapy. Here, we assessed whether the use of the antioxidants hydroxytyrosol (HT)…”
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Impact of Musashi-1 and Musashi-2 Double Knockdown on Notch Signaling and the Pathogenesis of Endometriosis
Published in International journal of molecular sciences (05-03-2022)“…The stem cell marker and RNA-binding protein Musashi-1 is overexpressed in endometriosis. Musashi-1-siRNA knockdown in Ishikawa cells altered the expression of…”
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The Cell Surface Heparan Sulfate Proteoglycan Syndecan-3 Promotes Ovarian Cancer Pathogenesis
Published in International journal of molecular sciences (21-05-2022)“…Syndecans are transmembrane heparan sulfate proteoglycans that integrate signaling at the cell surface. By interacting with cytokines, signaling receptors,…”
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A Shift Towards an Immature Myeloid Profile in Peripheral Blood of Critically Ill COVID-19 Patients
Published in Archives of medical research (01-04-2021)“…SARS-CoV-2, the etiological agent causing COVID-19, has infected more than 27 million people with over 894000 deaths worldwide since its emergence in December…”
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Enzymatic Digestion of Cell-surface Heparan Sulfate Alters the Radiation Response in Triple-negative Breast Cancer Cells
Published in Archives of medical research (01-12-2022)“…Radiation resistance represents a major challenge in the treatment of breast cancer. As heparan sulfate (HS) chains are known to contribute to tumorigenesis,…”
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Differential impact of classical and non-canonical NF-κB pathway-related gene expression on the survival of breast cancer patients
Published in Journal of Cancer (01-01-2019)“…Inflammation is a well-known driver of carcinogenesis and cancer progression, often attributed to the tumor microenvironment. However, tumor cells themselves…”
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Analyzing the Communication Between Monocytes and Primary Breast Cancer Cells in an Extracellular Matrix Extract (ECME)-based Three-dimensional System
Published in Journal of visualized experiments (08-01-2018)“…Embedded in the extracellular matrix (ECM), normal and neoplastic epithelial cells intimately communicate with hematopoietic and non-hematopoietic cells, thus…”
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Corrigendum: IL-1β, IL-8, and Matrix Metalloproteinases-1, -2, and -10 Are Enriched upon Monocyte-Breast Cancer Cell Cocultivation in a Matrigel-Based Three-Dimensional System
Published in Frontiers in immunology (27-07-2017)“…[This corrects the article on p. 205 in vol. 8, PMID: 28337194.]…”
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Proteoglycan Expression Studied by MicroRNAs
Published in Methods in molecular biology (Clifton, N.J.) (2023)“…MicroRNAs are small noncoding RNAs that regulate gene expression at the posttranscriptional level. Proteoglycans are glycoproteins characterized by covalent…”
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IL-1β, IL-8, and Matrix Metalloproteinases-1, -2, and -10 Are Enriched upon Monocyte-Breast Cancer Cell Cocultivation in a Matrigel-Based Three-Dimensional System
Published in Frontiers in immunology (08-03-2017)“…Breast cancer remains the first cancer-related cause of death in women worldwide, particularly in developing countries in which most cases are diagnosed in…”
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An NFκB-dependent mechanism of tumor cell plasticity and lateral transmission of aggressive features
Published in Oncotarget (01-06-2018)“…Breast cancer is a complex disease exhibiting extensive inter- and intra-tumor heterogeneity. Inflammation is a well-known driver of cancer progression, often…”
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