Search Results - "Espinoza, J. Luis"

Dietary phytochemicals and cancer chemoprevention: a review of the clinical evidence by Kotecha, Ritesh, Takami, Akiyoshi, Espinoza, J Luis

“…Cancer chemoprevention involves the use of different natural or biologic agents to inhibit or reverse tumor growth. Epidemiological and pre-clinical data…”
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Gastric microbiota: An emerging player in Helicobacter pylori-induced gastric malignancies by Espinoza, J. Luis, Matsumoto, Ayumi, Tanaka, Hirokazu, Matsumura, Itaru

“…The complex diversity of nonpathogenic microbes that colonize the human body, known as microbiota, exert considerable effects on physiological homeostasis, and…”
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Fluke-Related Cholangiocarcinoma: Challenges and Opportunities by Espinoza, J Luis

“…Cholangiocarcinoma encompasses a heterogeneous group of highly aggressive malignancies, arising from the biliary tract, that are often associated with poor…”
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Chlorpromazine eliminates acute myeloid leukemia cells by perturbing subcellular localization of FLT3-ITD and KIT-D816V by Rai, Shinya, Tanaka, Hirokazu, Suzuki, Mai, Espinoza, J. Luis, Kumode, Takahiro, Tanimura, Akira, Yokota, Takafumi, Oritani, Kenji, Watanabe, Toshio, Kanakura, Yuzuru, Matsumura, Itaru

“…Mutated receptor tyrosine kinases (MT-RTKs) such as internal tandem duplication of FMS-like tyrosine kinase 3 (FLT3 ITD) and a point mutation KIT D816V are…”
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Sensing Bacterial-Induced DNA Damaging Effects via Natural Killer Group 2 Member D Immune Receptor: From Dysbiosis to Autoimmunity and Carcinogenesis by Espinoza, J Luis, Minami, Mika

“…The human genome is constantly exposed to exogenous and endogenous DNA damaging factors that frequently cause DNA damages. Unless repaired, damaged DNA can…”
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Projecting home nurse workforce needs for the next two decades for the super‐aging population of Japan by Kamio, Kosuke, Espinoza, J. Luis

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Host-microbe interactions in the pathogenesis and clinical course of sarcoidosis by Inaoka, Pleiades T, Shono, Masato, Kamada, Mishio, Espinoza, J Luis

“…Sarcoidosis is a rare inflammatory disease characterized by the development of granulomas in various organs, especially in the lungs and lymph nodes. Clinics…”
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Rationale for assessing the therapeutic potential of resveratrol in hematological malignancies by Espinoza, J. Luis, Kurokawa, Yu, Takami, Akiyoshi

“…Promising results from pre-clinical studies on the naturally-occurring polyphenol resveratrol have generated considerable interest and somewhat excessive…”
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MAIT Cells in the Bone Marrow of Patients with Aplastic Anemia by Vu, Lam Quang, Espinoza, J Luis, Nguyen, Hoang Thao Giang, Mizuno, Shohei, Takami, Akiyoshi

“…Mucosal-associated invariant T cells (MAIT cells) are a subset of T cells with innate, effector-like properties that play an essential role in the immune…”
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A genetic variant in the IL-17 promoter is functionally associated with acute graft-versus-host disease after unrelated bone marrow transplantation by Espinoza, J Luis, Takami, Akiyoshi, Nakata, Katsuya, Onizuka, Makoto, Kawase, Takakazu, Akiyama, Hideki, Miyamura, Koichi, Morishima, Yasuo, Fukuda, Takahiro, Kodera, Yoshihisa, Nakao, Shinji

“…Interleukin IL-17 is a proinflammatory cytokine that has been implicated in the pathogenesis of various autoimmune diseases. The single nucleotide polymorphism…”
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The Impact of NLRP3 Activation on Hematopoietic Stem Cell Transplantation by Espinoza, J Luis, Kamio, Kosuke, Lam, Vu Quang, Takami, Akiyoshi

“…NLR family pyrin domain-containing 3 (NLRP3) is an intracellular protein that after recognizing a broad spectrum of stressors, such as microbial motifs and…”
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Resveratrol induces cell cycle arrest and apoptosis in malignant NK cells via JAK2/STAT3 pathway inhibition by Quoc Trung, Ly, Espinoza, J Luis, Takami, Akiyoshi, Nakao, Shinji

“…Natural killer (NK) cell malignancies, particularly aggressive NK cell leukaemias and lymphomas, have poor prognoses. Although recent regimens with…”
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Human microRNA-1245 down-regulates the NKG2D receptor in natural killer cells and impairs NKG2D-mediated functions by LUIS ESPINOZA, J, TAKAMI, Akiyoshi, YOSHIOKA, Katsuji, NAKATA, Katsuya, SATO, Tokiharu, KASAHARA, Yoshihito, NAKAO, Shinji

“…NKG2D is an activating receptor expressed by natural killer and T cells, which have crucial functions in tumor and microbial immunosurveillance. Several…”
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Ataxia–telangiectasia mutated kinase‐mediated upregulation of NKG2D ligands on leukemia cells by resveratrol results in enhanced natural killer cell susceptibility by Luis Espinoza, J., Takami, Akiyoshi, Trung, Ly Q., Nakao, Shinji

“…The powerful activating receptor NKG2D is expressed by natural killer (NK) cells and promotes cytotoxic lysis of cancer cells expressing NKG2D ligands…”
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The Predominance of Klebsiella aerogenes among Carbapenem-Resistant Enterobacteriaceae Infections in Japan by Kamio, Kosuke, Espinoza, J. Luis

“…The emergence of carbapenem-resistant Enterobacteriaceae (CRE) is an important public health issue worldwide, not only due to the potential of these pathogens…”
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Donor UNC-93 Homolog B1 genetic polymorphism predicts survival outcomes after unrelated bone marrow transplantation by Uchino, Kaori, Vu Quang, Lam, Mizuno, Shohei, Horio, Tomohiro, Yamamoto, Hidesuke, Hanamura, Ichiro, Kodera, Yoshihisa, Luis Espinoza, J., Onizuka, Makoto, Kashiwase, Koichi, Morishima, Yasuo, Fukuda, Takahiro, Doki, Noriko, Miyamura, Koichi, Mori, Takehiko, Morishita, Eriko, Nakao, Shinji, Takami, Akiyoshi

“…UNC-93 homolog B1 (UNC93B1) is a key regulator of toll-like receptors (TLRs), pattern recognition receptors that sense invading pathogens and manage the innate…”
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Resveratrol prevents EBV transformation and inhibits the outgrowth of EBV-immortalized human B cells by Espinoza, J Luis, Takami, Akiyoshi, Trung, Ly Quoc, Kato, Shunichi, Nakao, Shinji

“…Epstein Barr virus-associated lymphoproliferative disease is an increasing complication in patients with immunosuppressive conditions. Although the current…”
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A functional polymorphism in the NKG2D gene modulates NK-cell cytotoxicity and is associated with susceptibility to Human Papilloma Virus-related cancers by Espinoza, J. Luis, Nguyen, Viet H., Ichimura, Hiroshi, Pham, Trang T. T., Nguyen, Cuong H., Pham, Thuc V., Elbadry, Mahmoud I., Yoshioka, Katsuji, Tanaka, Junji, Trung, Ly Q., Takami, Akiyoshi, Nakao, Shinji

“…Human papillomavirus (HPV) is the most common sexually transmitted agent worldwide and is etiologically linked to several cancers, including cervical and…”
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The Host-Microbe Interplay in Human Papillomavirus-Induced Carcinogenesis by Wakabayashi, Rei, Nakahama, Yusuke, Nguyen, Viet, Espinoza, J Luis

“…Every year nearly half a million new cases of cervix cancer are diagnosed worldwide, making this malignancy the fourth commonest cancer in women. In 2018, more…”
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The Impact of COVID-19 Pandemic on ESBL-Producing Enterobacterales Infections: A Scoping Review by Mai, Ha Thi Thao, Espinoza, J Luis

“…Several studies have reported an increased frequency of colonization and/or infection with antibiotic-resistant bacteria (ARB) during the COVID-19 pandemic…”
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