Search Results - "Espinosa Díaz, Ana"

Selective YAP/TAZ inhibition in fibroblasts via dopamine receptor D1 agonism reverses fibrosis by Haak, Andrew J, Kostallari, Enis, Sicard, Delphine, Ligresti, Giovanni, Choi, Kyoung Moo, Caporarello, Nunzia, Jones, Dakota L, Tan, Qi, Meridew, Jeffrey, Diaz Espinosa, Ana M, Aravamudhan, Aja, Maiers, Jessica L, Britt, Jr, Rodney D, Roden, Anja C, Pabelick, Christina M, Prakash, Y S, Nouraie, Seyed Mehdi, Li, Xiaoyun, Zhang, Yingze, Kass, Daniel J, Lagares, David, Tager, Andrew M, Varelas, Xaralabos, Shah, Vijay H, Tschumperlin, Daniel J

“…Tissue fibrosis is characterized by uncontrolled deposition and diminished clearance of fibrous connective tissue proteins, ultimately leading to organ…”
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Combined control of the fibroblast contractile program by YAP and TAZ by Link, Patrick A, Choi, Kyoung Moo, Diaz Espinosa, Ana M, Jones, Dakota L, Gao, Ashley Y, Haak, Andrew J, Tschumperlin, Daniel J

“…Yes-associated protein (YAP) and transcriptional coactivator with PDZ-binding motif (TAZ) are transcription cofactors implicated in the contractile and…”
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Dopamine D1 receptor stimulates cathepsin K-dependent degradation and resorption of collagen I in lung fibroblasts by Diaz-Espinosa, Ana M, Link, Patrick A, Sicard, Delphine, Jorba, Ignasi, Tschumperlin, Daniel J, Haak, Andrew J

“…Matrix resorption is essential to the clearance of the extracellular matrix (ECM) after normal wound healing. A disruption in these processes constitutes a…”
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GPCR‐mediated YAP/TAZ inactivation in fibroblasts via EPAC1/2, RAP2C, and MAP4K7 by Choi, Kyoung Moo, Haak, Andrew J., Diaz Espinosa, Ana M., Cummins, Katherine A., Link, Patrick A., Aravamudhan, Aja, Wood, David K., Tschumperlin, Daniel J.

“…Yes‐associated protein (YAP) and PDZ‐binding motif (TAZ) have emerged as important regulators of pathologic fibroblast activation in fibrotic diseases. Agonism…”
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Targeting GPCR Signaling for Idiopathic Pulmonary Fibrosis Therapies by Haak, Andrew J., Ducharme, Merrick T., Diaz Espinosa, Ana M., Tschumperlin, Daniel J.

“…A variety of G protein-coupled receptors (GPCRs) have been implicated in the pathogenesis of pulmonary fibrosis, largely through their promotion of profibrotic…”
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Pim-1 kinase is a positive feedback regulator of the senescent lung fibroblast inflammatory secretome by Gao, Ashley Y, Diaz Espinosa, Ana M, Gianì, Fiorenza, Pham, Tho X, Carver, Chase M, Aravamudhan, Aja, Bartman, Colleen M, Ligresti, Giovanni, Caporarello, Nunzia, Schafer, Marissa J, Haak, Andrew J

“…Cellular senescence is emerging as a driver of idiopathic pulmonary fibrosis (IPF), a progressive and fatal disease with limited effective therapies. The…”
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ZNF416 is a pivotal transcriptional regulator of fibroblast mechanoactivation by Jones, Dakota L, Meridew, Jeffrey A, Link, Patrick A, Ducharme, Merrick T, Lydon, Katherine L, Choi, Kyoung M, Caporarello, Nunzia, Tan, Qi, Diaz Espinosa, Ana Maria, Xiong, Yuning, Lee, Jeong-Heon, Ye, Zhenqing, Yan, Huihuang, Ordog, Tamas, Ligresti, Giovanni, Varelas, Xaralabos, Tschumperlin, Daniel J

“…Matrix stiffness is a central regulator of fibroblast function. However, the transcriptional mechanisms linking matrix stiffness to changes in fibroblast…”
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Dopamine Receptor D1 Is Exempt from Transforming Growth Factor β -Mediated Antifibrotic G Protein-Coupled Receptor Landscape Tampering in Lung Fibroblasts by Gao, Ashley Y, Diaz Espinosa, Ana M, Nguyen, Ba Bao N, Link, Patrick A, Meridew, Jeffrey, Jones, Dakota L, Gibbard, Daniel F, Tschumperlin, Daniel J, Haak, Andrew J

“…Pulmonary fibroblasts are the primary producers of extracellular matrix (ECM) in the lungs, and their pathogenic activation drives scarring and loss of lung…”
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Socioeconomic inequalities in urban and transport planning related exposures and mortality: A health impact assessment study for Bradford, UK by Mueller, Natalie, Rojas-Rueda, David, Khreis, Haneen, Cirach, Marta, Milà, Carles, Espinosa, Ana, Foraster, Maria, McEachan, Rosemary R.C., Kelly, Brian, Wright, John, Nieuwenhuijsen, Mark

“…Cities have unique geographic, environmental and sociocultural characteristics that influence the health status of their citizens. Identification and…”
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Effect of mistimed eating patterns on breast and prostate cancer risk (MCC‐Spain Study) by Kogevinas, Manolis, Espinosa, Ana, Castelló, Adela, Gómez‐Acebo, Inés, Guevara, Marcela, Martin, Vicente, Amiano, Pilar, Alguacil, Juan, Peiro, Rosana, Moreno, Victor, Costas, Laura, Fernández‐Tardón, Guillermo, Jimenez, Jose Juan, Marcos‐Gragera, Rafael, Perez‐Gomez, Beatriz, Llorca, Javier, Moreno‐Iribas, Conchi, Fernández‐Villa, Tania, Oribe, Madalen, Aragones, Nuria, Papantoniou, Kyriaki, Pollán, Marina, Castano‐Vinyals, Gemma, Romaguera, Dora

“…Modern life involves mistimed sleeping and eating patterns that in experimental studies are associated with adverse health effects. We assessed whether timing…”
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Genome-wide association study of offspring birth weight in 86 577 women identifies five novel loci and highlights maternal genetic effects that are independent of fetal genetics by Beaumont, Robin N, Espinosa Díaz, Ana, Kogevinas, Manolis, Estivill, Xavier, 1955

“…Genome-wide association studies of birth weight have focused on fetal genetics, whereas relatively little is known about the role of maternal genetic…”
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Evaluating the association between artificial light-at-night exposure and breast and prostate cancer risk in Spain (MCC-Spain study) by Garcia-Saenz, Ariadna, Espinosa Díaz, Ana, Valentín, Antònia, Castaño Vinyals, Gemma, Kogevinas, Manolis

“…BACKGROUND: Night shift work, exposure to light at night (ALAN) and circadian disruption may increase the risk of hormone-dependent cancers. OBJECTIVES: We…”
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Breast cancer risk and night shift work in a case-control study in a Spanish population by Papantoniou, Kyriaki, Castaño-Vinyals, Gemma, Espinosa, Ana, Aragonés, Nuria, Pérez-Gómez, Beatriz, Ardanaz, Eva, Altzibar, Jone Miren, Sanchez, Vicente Martin, Gómez-Acebo, Inés, Llorca, Javier, Muñoz, David, Tardón, Adonina, Peiró, Rosana, Marcos-Gragera, Rafael, Pollan, Marina, Kogevinas, Manolis

“…Epidemiologic and animal data indicate that night shift work might increase the risk for breast cancer. We evaluated the association of night work with…”
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Residential proximity to green spaces and breast cancer risk: The multicase-control study in Spain (MCC-Spain) by O'Callaghan-Gordo, Cristina, Kogevinas, Manolis, Cirach, Marta, Castaño-Vinyals, Gemma, Aragonés, Nuria, Delfrade, Josu, Fernández-Villa, Tania, Amiano, Pilar, Dierssen-Sotos, Trinidad, Tardon, Adonina, Capelo, Rocio, Peiró-Perez, Rosana, Moreno, Víctor, Roca-Barceló, Aina, Perez-Gomez, Beatriz, Vidan, Juana, Molina, Antonio José, Oribe, Madalen, Gràcia-Lavedan, Esther, Espinosa, Ana, Valentin, Antònia, Pollán, Marina, Nieuwenhuijsen, Mark J.

“…Breast cancer is the main cause of cancer mortality among women. Green spaces have been recently associated with reduced cancer mortality among women…”
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Trends and patterns in the use of computed tomography in children and young adults in Catalonia — results from the EPI-CT study by Bosch de Basea, Magda, Salotti, Jane A., Pearce, Mark S., Muchart, Jordi, Riera, Luis, Barber, Ignasi, Pedraza, Salvador, Pardina, Marina, Capdevila, Antoni, Espinosa, Ana, Cardis, Elisabeth

“…Background Although there are undeniable diagnostic benefits of CT scanning, its increasing use in paediatric radiology has become a topic of concern regarding…”
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First person – Ana Diaz Espinosa

“…First Person is a series of interviews with the first authors of a selection of papers published in Journal of Cell Science, helping early-career researchers…”
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Colorectal Cancer and Long-Term Exposure to Trihalomethanes in Drinking Water: A Multicenter Case-Control Study in Spain and Italy by Villanueva Belmonte, Cristina, Gracia Lavedan, Esther, Castaño Vinyals, Gemma, Espinosa Díaz, Ana, Espejo Herrera, Nadia Carminia, 1983, Nieuwenhuijsen, Mark J, Kogevinas, Manolis

“…BACKGROUND: Evidence on the association between colorectal cancer and exposure to disinfection by-products in drinking water is inconsistent. OBJECTIVES: We…”
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Actividad del tribunal constitucional: relación de sentencias dictadas durante el primer cuatrimestre de 2019 by Elvira Perales, Ascensión, Espinosa Díaz, Ana, Fraile Ortiz, María, Gómez Lugo, Yolanda, Baamonde Gómez, Laura

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Actividad del Tribunal Constitucional: relación de sentencias dictadas durante el tercer cuatrimestre de 2018 by Elvira Perales, Ascensión, Espinosa Díaz, Ana, Fraile Ortiz, María, Gómez Lugo, Yolanda, Baamonde Gómez, Laura

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Maternal diet during pregnancy and micronuclei frequency in peripheral blood T lymphocytes in mothers and newborns (Rhea cohort, Crete) by O’Callaghan-Gordo, Cristina, Kogevinas, Manolis, Pedersen, Marie, Fthenou, Eleni, Espinosa, Ana, Tsiapa, Xristina, Chalkiadaki, Georgia, Daraki, Vasiliki, Dermitzaki, Eirini, Decordier, Ilse, Farmer, Peter B., Georgiadis, Panagiotis, Georgiou, Vaggelis, Kyrtopoulos, Soterios A., Merlo, Domenico Franco, Romaguera, Dora, Roumeliotaki, Theano, Sarri, Katerina, Törnqvist, Margareta, Loock, Kim Vande, von Stedingk, Hans, Kleinjans, Jos, Kirsch-Volders, Micheline, Chatzi, Leda

“…Purpose The study assessed whether diet and adherence to cancer prevention guidelines during pregnancy were associated with micronucleus (MN) frequency in…”
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