Search Results - "Espie, David"

New insights into CAR T cell-mediated killing of tumor cells by Espie, David, Donnadieu, Emmanuel

“…Adoptive transfer of T cells genetically engineered to express chimeric antigen receptors (CAR) has demonstrated striking efficacy for the treatment of several…”
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CAR T-cell behavior and function revealed by real-time imaging by Espie, David, Donnadieu, Emmanuel

“…Adoptive transfer of T-cells expressing chimeric antigen receptors (CAR) has shown remarkable clinical efficacy against advanced B-cell malignancies…”
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CAR T cells targeting Aspergillus fumigatus are effective at treating invasive pulmonary aspergillosis in preclinical models by Seif, Michelle, Kakoschke, Tamara Katharina, Ebel, Frank, Bellet, Marina Maria, Trinks, Nora, Renga, Giorgia, Pariano, Marilena, Romani, Luigina, Tappe, Beeke, Espie, David, Donnadieu, Emmanuel, Hünniger, Kerstin, Häder, Antje, Sauer, Markus, Damotte, Diane, Alifano, Marco, White, P Lewis, Backx, Matthijs, Nerreter, Thomas, Machwirth, Markus, Kurzai, Oliver, Prommersberger, Sabrina, Einsele, Hermann, Hudecek, Michael, Löffler, Jürgen

“…is a ubiquitous mold that can cause severe infections in immunocompromised patients, typically manifesting as invasive pulmonary aspergillosis (IPA). Adaptive…”
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Live Imaging of CAR T Cell Ca 2+ Signals in Tumor Slices Using Confocal Microscopy by Espie, David, Barrin, Sarah, Rajnpreht, Irena, Vimeux, Lene, Donnadieu, Emmanuel

“…The immune synapse is a key structure organizing T-cell activation against foreign entities, such as cancer cells expressing neoantigens. One crucial step in…”
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Time to evolve: predicting engineered T cell-associated toxicity with next-generation models by Donnadieu, Emmanuel, Luu, Maik, Alb, Miriam, Anliker, Brigitte, Arcangeli, Silvia, Bonini, Chiara, De Angelis, Biagio, Choudhary, Rashmi, Espie, David, Galy, Anne, Holland, Cam, Ivics, Zoltán, Kantari-Mimoun, Chahrazade, Kersten, Marie Jose, Köhl, Ulrike, Kuhn, Chantal, Laugel, Bruno, Locatelli, Franco, Marchiq, Ibtissam, Markman, Janet, Moresco, Marta Angiola, Morris, Emma, Negre, Helene, Quintarelli, Concetta, Rade, Michael, Reiche, Kristin, Renner, Matthias, Ruggiero, Eliana, Sanges, Carmen, Stauss, Hans, Themeli, Maria, Van den Brulle, Jan, Hudecek, Michael, Casucci, Monica

“…Despite promising clinical results in a small subset of malignancies, therapies based on engineered chimeric antigen receptor and T-cell receptor T cells are…”
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Time 2EVOLVE: predicting efficacy of engineered T-cells - how far is the bench from the bedside? by Guedan, Sonia, Luu, Maik, Ammar, Delphine, Barbao, Paula, Bonini, Chiara, Bousso, Philippe, Buchholz, Christian J, Casucci, Monica, De Angelis, Biagio, Donnadieu, Emmanuel, Espie, David, Greco, Beatrice, Groen, Richard, Huppa, Johannes B, Kantari-Mimoun, Chahrazade, Laugel, Bruno, Mantock, Mary, Markman, Janet L, Morris, Emma, Quintarelli, Concetta, Rade, Michael, Reiche, Kristin, Rodriguez-Garcia, Alba, Rodriguez-Madoz, Juan Roberto, Ruggiero, Eliana, Themeli, Maria, Hudecek, Michael, Marchiq, Ibtissam

“…Immunotherapy with gene engineered CAR and TCR transgenic T-cells is a transformative treatment in cancer medicine. There is a rich pipeline with target…”
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Nonlinear transformations for parameter estimation by Espie, David M., Macchietto, Sandro

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The use of nonlinear parameter estimation for dynamic chemical reactor modelling by Espie, David Miller

“…This thesis studies the application of nonlinear parameter estimation to dynamic models arising from transient chemical reactions. The models consist of…”
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