Search Results - "Espana, Edgar"

Composition, structure and function of the corneal stroma by Espana, Edgar M., Birk, David E.

“…No other tissue in the body depends more on the composition and organization of the extracellular matrix (ECM) for normal structure and function than the…”
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Ocular Surface Fibroma: A Rare, Benign Tumor of the Conjunctiva by Weppelmann, Thomas A., Margo, Curtis E., Espana, Edgar M.

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Collagen XII Regulates Corneal Stromal Structure by Modulating Transforming Growth Factor-β Activity by Sun, Mei, Koudouna, Elena, Cogswell, Devon, Avila, Marcel Y., Koch, Manuel, Espana, Edgar M.

“…Collagen XII is a regulator of corneal stroma structure and function. The current study examined the role of collagen XII in regulating corneal stromal…”
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Diseases of the corneal endothelium by Jeang, Lauren J., Margo, Curtis E., Espana, Edgar M.

“…The corneal endothelial monolayer and associated Descemet's membrane (DM) complex is a unique structure that plays an essential role in corneal function…”
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Amelanotic Melanoma Masquerading as Ocular Surface Squamous Neoplasia by Weppelmann, Thomas A, Margo, Curtis E, Espana, Edgar M

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Fungal keratitis: Mechanisms of infection and management strategies by Donovan, Christopher, Arenas, Eduardo, Ayyala, Ramesh S, Margo, Curtis E, Espana, Edgar M.

“…Fungal corneal ulcers are an uncommon, yet challenging, cause of vision loss. In the United States, geographic location appears to dictate not only the…”
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Large Conjunctival Ulceration from Ocular Monkeypox by Weppelmann, Thomas A., Wadia, Hormuz P., Espana, Edgar M.

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A Core of Keratocan-Negative Cells Survives in Old Corneal Scars by Joud, Hadi, Asgari, Meisam, Emerick, Victoria, Sun, Mei, Avila, Marcel Y., Margo, Curtis E., Espana, Edgar M.

“…Corneal scars originate from keratocyte-derived fibroblasts and myofibroblasts that are ultimately cleared through apoptosis or revert to keratocytes. A mouse…”
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Keratocyte-Derived Myofibroblasts: Functional Differences With Their Fibroblast Precursors by Acosta, Ana C, Joud, Hadi, Sun, Mei, Avila, Marcel Y, Margo, Curtis E, Espana, Edgar M

“…In this study, we aim to elucidate functional differences between fibroblasts and myofibroblasts derived from a keratocyte lineage to better understand corneal…”
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Dysfunctional latent transforming growth factor β activation after corneal injury in a classical Ehlers–Danlos model by Sun, Mei, Acosta, Ana Carolina, Emerick, Victoria, Adams, Sheila, Avila, Marcel Y, Margo, Curtis E, Espana, Edgar M

“…•Col5a1+/- corneas heal poorly after incisional injuries with persistence of open wounds and larger scars.•Col5a1+/− myofibroblasts failed to activate latent…”
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Collagen V insufficiency in a mouse model for Ehlers Danlos-syndrome affects viscoelastic biomechanical properties explaining thin and brittle corneas by Kling, Sabine, Torres-Netto, Emilio A., Abdshahzadeh, Hormoz, Espana, Edgar M., Hafezi, Farhad

“…Ehlers–Danlos syndrome (EDS) is a genetic disease leading to abnormalities in mechanical properties of different tissues. Here we quantify corneal…”
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Collagen XII regulates stromal wound closure by Donovan, Christopher, Cogswell, Devon, Sun, Mei, Adams, Sheila, Avila, Marcel Y., Margo, Curtis E., Koch, Manuel, Espana, Edgar M.

“…The role of collagen XII in regulating injury repair and reestablishment of corneal function is unknown. This manuscript aims to investigate the role(s) of…”
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Molecular nature of ocular surface barrier function, diseases that affect it, and its relevance for ocular drug delivery by Kaur, Satinder, Sohnen, Peri, Swamynathan, Sudha, Du, Yiqin, Espana, Edgar M, Swamynathan, Shivalingappa K

“…The structural and functional integrity of the ocular surface, a continuous epithelial structure comprised of the cornea, the conjunctiva, and the ductal…”
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Collagen XII Is a Regulator of Corneal Stroma Structure and Function by Sun, Mei, Zafrullah, Nabeel, Devaux, Floriane, Hemmavanh, Chinda, Adams, Sheila, Ziebarth, Noel M, Koch, Manuel, Birk, David E, Espana, Edgar M

“…The aim of this study was to determine the roles of collagen XII in the regulation of stromal hierarchical organization, keratocyte organization, and corneal…”
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Multiple Optical Elastography Techniques Reveal the Regulation of Corneal Stiffness by Collagen XII by Nair, Achuth, Ambekar, Yogeshwari S, Zevallos-Delgado, Christian, Mekonnen, Taye, Sun, Mei, Zvietcovich, Fernando, Singh, Manmohan, Aglyamov, Salavat, Koch, Manuel, Scarcelli, Giuliano, Espana, Edgar M, Larin, Kirill V

“…Collagen XII plays a role in regulating the structure and mechanical properties of the cornea. In this work, several optical elastography techniques were used…”
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Collagen XIV Is an Intrinsic Regulator of Corneal Stromal Structure and Function by Sun, Mei, Zafrullah, Nabeel, Adams, Sheila, Devaux, Floriane, Avila, Marcel Y., Ziebarth, Noel, Margo, Curtis E., Koch, Manuel, Espana, Edgar M.

“…Collagen XIV is poorly characterized in the body, and the current knowledge of its function in the cornea is limited. The aim of the current study was to…”
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Existence of Corneal Endothelial Slow-Cycling Cells by Espana, Edgar M, Sun, Mei, Birk, David E

“…To demonstrate the presence and location of corneal endothelial progenitor cells. Progenitor cell markers nestin, leucine-rich repeat-containing…”
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Clinical Outcomes and Patient Satisfaction After Corneal Neurotization by Rafailov, Leon, Kim, Jane S., Wisely, Clayton Ellis, Espana, Edgar M., Soifer, Matias, Leyngold, Ilya M.

“…The aim of this study was to assess clinical outcomes of corneal neurotization (CN) and determine patient perception of postoperative results. This was a…”
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Downregulation of collagen XI during late postnatal corneal development is followed by upregulation after injury by Sun, Mei, Cogswell, Devon, Adams, Sheila, Ayoubi, Yasmin, Kumar, Ambuj, Reljic, Tea, Avila, Marcel Y, Margo, Curtis E, Espana, Edgar M

“…Collagen XI plays a role in nucleating collagen fibrils and in controlling fibril diameter. The aim of this research was to elucidate the role that collagen XI…”
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Creation and grading of experimental corneal scars in mice models by Cogswell, Devon, Sun, Mei, Greenberg, Erin, Margo, Curtis E., Espana, Edgar M.

“…To develop a stromal wound healing model and a reliable scar classification score system that correlates photographic evaluation with changes in the structure…”
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