Search Results - "Espírito Santo, Renan Fernandes do"

Pharmacological Properties of Riparin IV in Models of Pain and Inflammation by Nascimento, Olívia Azevêdo, Espírito-Santo, Renan Fernandes do, Opretzka, Luíza Carolina França, Barbosa-Filho, José Maria, Gutierrez, Stanley Juan Chavez, Villarreal, Cristiane Flora, Soares, Milena Botelho Pereira

“…Riparins, natural alkaloids of the alkamide group, can be synthesized by simple methods, enhancing their potential application in pharmaceutical development…”
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Antinociceptive compounds and LC-DAD-ESIMSn profile from Dictyoloma vandellianum leaves by Abreu, Lucas Silva, Alves, Iura Muniz, Espírito Santo, Renan Fernandes do, Nascimento, Yuri Mangueira do, Dantas, César Augusto Gonçalves, Dos Santos, Gisele Graça Leite, Le Hyaric, Mireille, Guedes, Maria Lenise Silva, da Silva, Marcelo Sobral, Villarreal, Cristiane Flora, Velozo, Eudes da Silva, Tavares, Josean Fechine

“…Limonoids, quinolone alkaloids and chromones have been reported as constituents of Dictyoloma vandellianum Adr. Juss. (Rutaceae). Although those compounds are…”
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Betulinic Acid Derivative BA5, Attenuates Inflammation and Fibrosis in Experimental Chronic Chagas Disease Cardiomyopathy by Inducing IL-10 and M2 Polarization by Meira, Cássio Santana, Santos, Emanuelle De Souza, Santo, Renan Fernandes do Espírito, Vasconcelos, Juliana Fraga, Orge, Iasmim Diniz, Nonaka, Carolina Kymie Vasques, Barreto, Breno Cardim, Caria, Alex Cleber Improta, Silva, Daniela Nascimento, Barbosa-Filho, José Maria, Macambira, Simone Garcia, Moreira, Diogo Rodrigo Magalhães, Soares, Milena Botelho Pereira

“…Chronic Chagas disease cardiomyopathy (CCC) is a major cause of heart disease in Latin America and treatment for this condition is unsatisfactory. Here we…”
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Fluorescent Canthin‐6‐one Alkaloids from Simaba bahiensis: Isolation, Identification, and Cell‐Labeling Properties by dos Santos Costa, Rafael, do Espírito‐Santo, Renan Fernandes, Abreu, Lucas Silva, de Oliveira Aguiar, Leonardo, Leite Fontes, Dara, Fechine Tavares, Josean, Sobral da Silva, Marcelo, Botelho Pereira Soares, Milena, da Silva Velozo, Eudes, Flora Villarreal, Cristiane

“…Canthin‐6‐one alkaloids, which are present in plants of the genus Simaba, are natural compounds that are capable of acting as fluorescent probes. However, the…”
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Natural chromones as potential anti-inflammatory agents: Pharmacological properties and related mechanisms by Opretzka, Luiza Carolina França, Espírito-Santo, Renan Fernandes do, Nascimento, Olívia Azevedo, Abreu, Lucas Silva, Alves, Iura Muniz, Döring, Eva, Soares, Milena Botelho Pereira, Velozo, Eudes da Silva, Laufer, Stefan A., Villarreal, Cristiane Flora

“…Chromones are a group of natural substances with a diversity of biological activities. Herein we assessed the pharmacological potential of three chromones (1,…”
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Mesenchymal stem cells reduce the oxaliplatin-induced sensory neuropathy through the reestablishment of redox homeostasis in the spinal cord by dos Santos, Gisele Graça Leite, Oliveira, Anna Lethícia Lima, Santos, Dourivaldo Silva, do Espírito Santo, Renan Fernandes, Silva, Daniela Nascimento, Juiz, Paulo José Lima, Soares, Milena Botelho Pereira, Villarreal, Cristiane Flora

“…The present study was designed to investigate whether the antinociceptive effect of bone marrow-derived mesenchymal stem/stromal cells (MSC) during oxaliplatin…”
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Tonantzitlolone B Modulates the Endogenous Opioid System to Promote Antinociception in Mice by do Espírito-Santo, Renan Fernandes, Santos, Dourivaldo Silva, Sales Lauria, Pedro Santana, de Lima, Alyne Almeida, Abreu, Lucas Silva, Tavares, Josean Fechine, Castilho, Marcelo Santos, Pereira Soares, Milena Botelho, Villarreal, Cristiane Flora

“…Tonantzitlolone B (TZL-B) is a diterpene isolated from the roots of . Its antinociceptive effects were investigated in male Swiss mice using the following…”
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Unveiling Targets for Treating Postoperative Pain: The Role of the TNF-α/p38 MAPK/NF-κB/Nav1.8 and Nav1.9 Pathways in the Mouse Model of Incisional Pain by de Lima, Flávia Oliveira, Lauria, Pedro Santana Sales, do Espírito-Santo, Renan Fernandes, Evangelista, Afrânio Ferreira, Nogueira, Tâmara Magalhães Oliveira, Araldi, Dionéia, Soares, Milena Botelho Pereira, Villarreal, Cristiane Flora

“…Although the mouse model of incisional pain is broadly used, the mechanisms underlying plantar incision-induced nociception are not fully understood. This work…”
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Nitrite-negative results in urinary tract infection by Enterobacterales: does the nitrite dipstick test have low sensitivity? by Lopes Araújo-Filho, Carlos Eduardo, Santos Galvão, Vívian, Fernandes do Espírito Santo, Renan, de Souza Santos Monteiro, Adriano, Vargas Lordelo, Cassia, de Abreu Santos, Julio Cezar, Alves da Silva Junior, Valter, Machado Cordeiro, Soraia, David Couto, Ricardo

“…Urinary tract infection (UTI) is one of the most common bacterial infections among humans. Urine culture is the gold standard diagnostic method for UTI;…”
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Preclinical Pharmacokinetic Study and Lung Penetration of a Coumarin Extracted from Zanthoxylum tingoassuiba by Santos, Valdeene Vieira, da Hora Borges, Matheus Antônio, Jatobá da Silva, Karoline Cristina, Dos Santos Costa, Rafael, Santo, Renan Fernandes do Espírito, Velozo, Eudes da Silva, Villarreal, Cristiane Flora, Azeredo, Francine Johansson

“…The compound 6-methoxyseselin, derived from , demonstrates various therapeutic properties, including vasorelaxation, antinociceptive, anti-inflammatory, and…”
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Inhaled braylin regulates Th2 response and induces relaxant effects in the airway muscles in a model of ovalbumin-induced asthma by Espírito-Santo, Renan Fernandes do, Meira, Cássio Santana, Opretzka, Luiza Carolina França, da Silva, Karoline Cristina Jatobá, de Araújo, Fênix Alexandra, Costa, Rafael dos Santos, Velozo, Eudes Silva, Formiga, Fabio Rocha, Silva, Darizy Flávia, Soares, Milena Botelho Pereira, Villarreal, Cristiane Flora

“…•Inhaled braylin has consistent pharmacological properties on asthmatic mice.•Braylin regulates the Th2 response and reduces mucus production on asthmatic…”
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Structural improvement of new thiazolidinones compounds with antinociceptive activity in experimental chemotherapy‐induced painful neuropathy by Moreira, Diogo Rodrigo Magalhaes, Santos, Dourivaldo Silva, Espírito Santo, Renan Fernandes do, Santos, Flávia Evangelista dos, Oliveira Filho, Gevanio Bezerra, Leite, Ana Cristina Lima, Soares, Milena Botelho Pereira, Villarreal, Cristiane Flora

“…Chemotherapy‐induced neuropathy is a disabling pain condition resulting from chemotherapy for cancers. Up to now, no drug is available to cure…”
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The Compound (E) -2-Cyano- N ,3-diphenylacrylamide (JMPR-01): A Potential Drug for Treatment of Inflammatory Diseases by da Silva, Pablo Rayff, do Espírito Santo, Renan Fernandes, Melo, Camila de Oliveira, Pachú Cavalcante, Fábio Emanuel, Costa, Thássia Borges, Barbosa, Yasmim Vilarim, E Silva, Yvnni M S de Medeiros, de Sousa, Natália Ferreira, Villarreal, Cristiane Flora, de Moura, Ricardo Olímpio, Dos Santos, Vanda Lucia

“…The compound -2-cyano- ,3-diphenylacrylamide (JMPR-01) was structurally developed using bioisosteric modifications of a hybrid prototype as formed from…”
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Physalis angulata concentrated ethanolic extract suppresses nociception and inflammation by modulating cytokines and prostanoids pathways by do Espírito Santo, Renan Fernandes, Lima, Milena da Silva, Juiz, Paulo José Lima, Opretzka, Luíza Carolina França, Nogueira, Renata Campos, Ribeiro, Ivone Maria, Tomassini, Therezinha Coelho Barbosa, Soares, Milena Botelho Pereira, Villarreal, Cristiane Flora

“…Physalins are seco-steroids with a variety of pharmacological activities already described. In this study the pharmacological properties of a standardized…”
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Bisphosphonates: Pharmacokinetics, bioavailability, mechanisms of action, clinical applications in children, and effects on tooth development by Soares, Ana Prates, do Espírito Santo, Renan Fernandes, Line, Sérgio Roberto Peres, Pinto, Maria das Graças Farias, Santos, Pablo de Moura, Toralles, Maria Betânia Pereira, do Espírito Santo, Alexandre Ribeiro

“…Abstract Bisphosphonates (BPs) avidly bind to calcium crystals and inhibit osteoclastic bone resorption, making them useful for treatment of skeletal disorders…”
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Pain-like behaviors and local mechanisms involved in the nociception experimentally induced by Latrodectus curacaviensis spider venom by Lauria, Pedro Santana Sales, Casais-e-Silva, Luciana Lyra, do Espírito-Santo, Renan Fernandes, de Souza, Claudio Maurício Vieira, Zingali, Russolina Benedeta, Caruso, Marjolly Brígido, Soares, Milena Botelho Pereira, Villarreal, Cristiane Flora

“…•LCV induces intense and dose-related nociception in mice.•TRPV1 channels contribute to LCV-induced nociception.•Local inflammation does not seem to play a…”
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Betulinic acid derivative BA5, a dual NF-kB/calcineurin inhibitor, alleviates experimental shock and delayed hypersensitivity by Meira, Cássio Santana, Espírito Santo, Renan Fernandes do, dos Santos, Tatiana Barbosa, Orge, Iasmim Diniz, Silva, Dahara Keyse Carvalho, Guimarães, Elisalva Teixeira, Aragão França, Luciana Souza de, Barbosa-Filho, José Maria, Moreira, Diogo Rodrigo Magalhães, Soares, Milena Botelho Pereira

“…Betulinic acid (BA) is a naturally occurring triterpenoid with several biological properties already described, including immunomodulatory activity. Here we…”
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Antinociceptive compounds and LC-DAD-ESIMS.sup.n profile from Dictyoloma vandellianum leaves by Abreu, Lucas Silva, Alves, Iura Muniz, Espírito Santo, Renan Fernandes do, Nascimento, Yuri Mangueira do, Dantas, César Augusto Gonçalves, dos Santos, Gisele Graça Leite, Le Hyaric, Mireille, Guedes, Maria Lenise Silva, da Silva, Marcelo Sobral, Villarreal, Cristiane Flora, Velozo, Eudes da Silva, Tavares, Josean Fechine

“…Limonoids, quinolone alkaloids and chromones have been reported as constituents of Dictyoloma vandellianum Adr. Juss. (Rutaceae). Although those compounds are…”
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Phenylpropanoids from Croton velutinus with cytotoxic, trypanocidal and anti-inflammatory activities by Abreu, Lucas Silva, do Nascimento, Yuri Mangueira, do Espirito-Santo, Renan Fernandes, Meira, Cássio Santana, Santos, Ivanilson Pimenta, Brandão, Railda Batista, Souto, Augusto Lopes, Guedes, Maria Lenise Silva, Soares, Milena Botelho Pereira, Villarreal, Cristiane Flora, da Silva, Marcelo Sobral, Velozo, Eudes da Silva, Tavares, Josean Fechine

“…This current study presents the phytochemical analysis of Croton velutinus, describing phenylpropanoids obtained from this species. The fractionation of the…”
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IGF-1 overexpression improves mesenchymal stem cell survival and promotes neurological recovery after spinal cord injury by Allahdadi, Kyan James, de Santana, Thaís Alves, Santos, Girlaine Café, Azevedo, Carine Machado, Mota, Roberta Alves, Nonaka, Carolina Kymie, Silva, Daniela Nascimento, Valim, Clarissa Xavier Resende, Figueira, Cláudio Pereira, Dos Santos, Washington Luis Conrado, do Espirito Santo, Renan Fernandes, Evangelista, Afrânio Ferreira, Villarreal, Cristiane Flora, Dos Santos, Ricardo Ribeiro, de Souza, Bruno Solano Freitas, Soares, Milena Botelho Pereira

“…Survival and therapeutic actions of bone marrow-derived mesenchymal stem cells (BMMSCs) can be limited by the hostile microenvironment present during acute…”
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