Search Results - "Esmat, G"

Increased recurrence rates of hepatocellular carcinoma after DAA therapy in a hepatitis C‐infected Egyptian cohort: A comparative analysis by El Kassas, M., Funk, A. L., Salaheldin, M., Shimakawa, Y., Eltabbakh, M., Jean, K., El Tahan, A., Sweedy, A. T., Afify, S., Youssef, N. F., Esmat, G., Fontanet, A.

“…Summary In Egypt, hepatocellular carcinoma (HCC) is the most common form of cancer and direct‐acting antivirals (DAA) are administered on a large scale to…”
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National treatment programme of hepatitis C in Egypt: Hepatitis C virus model of care by El‐Akel, W., El‐Sayed, M. H., El Kassas, M., El‐Serafy, M., Khairy, M., Elsaeed, K., Kabil, K., Hassany, M., Shawky, A., Yosry, A., Shaker, M. K., ElShazly, Y., Waked, I., Esmat, G., Doss, W.

“…Summary Hepatitis C virus (HCV) infection is a major health problem in Egypt as the nation bears the highest prevalence rate worldwide. This necessitated…”
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Sofosbuvir‐based treatment regimens: real life results of 14 409 chronic HCV genotype 4 patients in Egypt by Elsharkawy, A., Fouad, R., El Akel, W., El Raziky, M., Hassany, M., Shiha, G., Said, M., Motawea, I., El Demerdash, T., Seif, S., Gaballah, A., El Shazly, Y., Makhlouf, M. A. M., Waked, I., Abdelaziz, A. O., Yosry, A., El Serafy, M., Thursz, M., Doss, W., Esmat, G.

“…Summary Background Chronic hepatitis C virus infection is one of the most important health problems in Egypt. The Ministry of Health's National Treatment…”
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Generic daclatasvir plus sofosbuvir, with or without ribavirin, in treatment of chronic hepatitis C: real‐world results from 18 378 patients in Egypt by Omar, H., El Akel, W., Elbaz, T., El Kassas, M., Elsaeed, K., El Shazly, H., Said, M., Yousif, M., Gomaa, A. A., Nasr, A., AbdAllah, M., Korany, M., Ismail, S. A., Shaker, M. K., Doss, W., Esmat, G., Waked, I., El Shazly, Y.

“…Summary Background Treatment of chronic hepatitis C using combination of sofosbuvir (SOF) and daclatasvir (DCV) was used in several clinical trials and…”
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miR-615-5p is restrictedly expressed in cirrhotic and cancerous liver tissues and its overexpression alleviates the tumorigenic effects in hepatocellular carcinoma by El Tayebi, H.M., Hosny, K.A., Esmat, G., Breuhahn, K., Abdelaziz, Ahmed Ihab

“…► miR-615-5p expression was absent in healthy liver tissues. ► miR-615-5p was detectable in cirrhotic, HCC tissues and cell lines. ► miR-615-5p mimicking…”
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Towards realistic estimates of HCV incidence in Egypt by Breban, R., Doss, W., Esmat, G., Elsayed, M., Hellard, M., Ayscue, P., Albert, M., Fontanet, A., Mohamed, M. K.

“…Summary Accurate incidence estimates are essential for quantifying hepatitis C virus (HCV) epidemic dynamics and monitoring the effectiveness of public health…”
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Does the long noncoding RNA HULC act as a sponge or as a downstream target for miR-186 in hepatocellular carcinoma? by Habashy, D.A., Hosny, K.A., Esmat, G., Abdelaziz, A.I.

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Human immunodeficiency virus (HIV) and coronavirus disease 2019; impact on vulnerable populations and harnessing lessons learnt from HIV programmes by Cordie, A., AbdAllah, M., Vergori, A., Kharono, B., Karkouri, M., Esmat, G.

“…Coronavirus disease 2019 (COVID-19) can act as a dual prong attack against management of people living with human immunodeficiency virus (HIV); it induces harm…”
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Epigallochatechin Gallate Stimulates the Expression of the MIRNAS, MIR-122, -200c, -155 and -182 and Decreases Viral Entry in HCV Infected Cells through Repressing Tight Junction Proteins, Occludin and Claudin-1 by Riad, S.E, Elhelw, D.S, Esmat, G, Abdelaziz, A.I

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The state of hepatitis B and C in Europe: report from the hepatitis B and C summit conference by Hatzakis, A., Wait, S., Bruix, J., Buti, M., Carballo, M., Cavaleri, M., Colombo, M., Delarocque-Astagneau, E., Dusheiko, G., Esmat, G., Esteban, R., Goldberg, D., Gore, C., Lok, A. S. F., Manns, M., Marcellin, P., Papatheodoridis, G., Peterle, A., Prati, D., Piorkowsky, N., Rizzetto, M., Roudot-Thoraval, F., Soriano, V., Thomas, H. C., Thursz, M., Valla, D., van Damme, P., Veldhuijzen, I. K., Wedemeyer, H., Wiessing, L., Zanetti, A. R., Janssen, H. L. A.

“…Worldwide, the hepatitis B virus (HBV) and the hepatitis C virus (HCV) cause, respectively, 600 000 and 350 000 deaths each year. Viral hepatitis is the…”
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The association of single nucleotide polymorphisms of Toll-like receptor 3, Toll-like receptor 7 and Toll-like receptor 8 genes with the susceptibility to HCV infection by El-Bendary, M, Neamatallah, M, Elalfy, H, Besheer, T, Elkholi, A, El-Diasty, M, Elsareef, M, Zahran, M, El-Aarag, B, Gomaa, A, Elhammady, D, El-Setouhy, M, Hegazy, A, Esmat, G

“…Background: Single nucleotide polymorphisms (SNPs) of Toll-like receptors (TLRs) are linked with functional modification of cytokine responses. In chronic…”
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The adverse effects of interferon‐free regimens in 149 816 chronic hepatitis C treated Egyptian patients by Attia, D., El Saeed, K., Elakel, W., El Baz, T., Omar, A., Yosry, A., Elsayed, M. H., Said, M., El Raziky, M., Anees, M., Doss, W., El Shazly, Y., Wedemeyer, H., Esmat, G.

“…Summary Background Interferon‐free regimens are associated with high sustained virological response; however, associated adverse effects have yet to be fully…”
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Whole-genome sequencing of human Pegivirus variant from an Egyptian patient co-infected with hepatitis C virus: a case report by Soliman, Hany K, Abouelhoda, Mohamed, El Rouby, Mahmoud N, Ahmed, Ola S, Esmat, G, Hassan, Zeinab K, Hafez, Mohammed M, Mehaney, Dina Ahmed, Selvaraju, Manojkumar, Darwish, Rania Kamal, Osman, Yehia A, Zekri, Abdel-Rahman N

“…Human pegivirus (HPgV) is structurally similar to hepatitis C virus (HCV) and was discovered 20 years ago. Its distribution, natural history and exact rule of…”
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Hepatitis C infection and clearance: impact on atherosclerosis and cardiometabolic risk factors by Mostafa, Aya, Mohamed, Mostafa K, Saeed, Mohamed, Hasan, Abubakr, Fontanet, Arnaud, Godsland, Ian, Coady, Emma, Esmat, Gamal, El-Hoseiny, Mostafa, Abdul-Hamid, Mohamed, Hughes, Alun, Chaturvedi, Nish

“…Chronic hepatitis C (HCV) infection is associated with diabetes and favourable lipids. To study the effect of this paradox on atherosclerosis and…”
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Comparison of liver biopsy and noninvasive techniques for liver fibrosis assessment in patients infected with HCV-genotype 4 in Egypt by Bonnard, P., Elsharkawy, A., Zalata, K., Delarocque-Astagneau, E., Biard, L., Le Fouler, L., Hassan, A. B., Abdel-Hamid, M., El-Daly, M., Gamal, M. E., El Kassas, M., Bedossa, P., Carrat, F., Fontanet, A., Esmat, G.

“…Summary In Egypt, as elsewhere, liver biopsy (LB) remains the gold standard to assess liver fibrosis in chronic hepatitis C (CHC) and is required to decide…”
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Role of Helicobacter pylori in patients with HCV-related chronic hepatitis and cirrhosis with or without hepatocellular carcinoma: possible association with disease progression by Esmat, G., El-Bendary, M., Zakarya, S., Ela, M. A., Zalata, K.

“…The discovery of Helicobacter hepaticus as a causal agent of hepatitis and hepatocellular carcinoma (HCC) in mice has stimulated interest in looking for…”
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Prevalence of thyroid dysfunction among 21672 Egyptian patients with chronic HCV genotype IV by Eletreby, R, Said, M, Abdellatif, Z, Saad, Y, El Serafy, M, Yosry, A, Waked, I, Esmat, G, Doss, W

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microRNA-34a and natural killer cells: an immuno-epigenetic approach to halt hepatocellular carcinoma progression by Abdelhamid, A.K, Yacoub, R.A, Fawzy, I.O, Gomaa, A, Hosny, K, Hamza, M.T, Esmat, G, Waked, I, Abdelaziz, A.I

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Validation of the role of FIB-4 and APRI in the assessment of hepatic fibrosis and prediction of risky varices in Egyptian patients with chronic hepatitis C (genotype 4) by El-Nahaas, S.M, Said, M, Soliman, Z.A, Saad, Y, El-Serafy, M, Yosry, A, Waked, I, Esmat, G, Doss, W

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Improvement of glycemic state among responders to sofosbuvir – based DAAs by Alem, S.A, Fouad, R, Elsharkawy, A, Adel, E, Abdellatif, Z, Musa, S, Nagy, A, Hussein, M.S, Yosry, A, Esmat, G

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