Search Results - "Esmaeili Mohsen Abadi, Sakineh"
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Tracking changes of the parameters of glucose-insulin homeostasis during the course of obesity in B6D2F1 mice
Published in Heliyon (01-01-2020)“…Obesity is one of the primary causes of type 2 diabetes mellitus (T2DM). To better understand how obesity impairs glucose-insulin homeostasis, we tracked…”
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Journal Article -
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Oral administration of SR-110, a peroxynitrite decomposing catalyst, enhances glucose homeostasis, insulin signaling, and islet architecture in B6D2F1 mice fed a high fat diet
Published in Archives of biochemistry and biophysics (15-04-2016)“…Peroxynitrite has been implicated in type 2 diabetes and diabetic complications. As a follow-up study to our previous work on SR-135 (Arch Biochem Biophys…”
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Journal Article -
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Estimation of insulin secretion, glucose uptake by tissues, and liver handling of glucose using a mathematical model of glucose-insulin homeostasis in lean and obese mice
Published in Heliyon (01-06-2017)“…Destruction of the insulin-producing β-cells is the key determinant of diabetes mellitus regardless of their types. Due to their anatomical location within the…”
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Journal Article -
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Investigating the Link between Obesity and Type 2 Diabetes Using Math Models and Simulation Optimization
Published 01-01-2015“…About 30 million people in the United States have diabetes. Over 90% of them have type 2 diabetes. Type 2 diabetes is caused by defects in insulin secretion by…”
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Dissertation