Search Results - "Eskander, N."

Real-world data from a molecular tumor board demonstrates improved outcomes with a precision N-of-One strategy by Kato, Shumei, Kim, Ki Hwan, Lim, Hyo Jeong, Boichard, Amelie, Nikanjam, Mina, Weihe, Elizabeth, Kuo, Dennis J., Eskander, Ramez N., Goodman, Aaron, Galanina, Natalie, Fanta, Paul T., Schwab, Richard B., Shatsky, Rebecca, Plaxe, Steven C., Sharabi, Andrew, Stites, Edward, Adashek, Jacob J., Okamura, Ryosuke, Lee, Suzanna, Lippman, Scott M., Sicklick, Jason K., Kurzrock, Razelle

“…Next-generation sequencing (NGS) can identify novel cancer targets. However, interpreting the molecular findings and accessing drugs/clinical trials is…”
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Clinical implications of plasma circulating tumor DNA in gynecologic cancer patients by Charo, Lindsey M., Eskander, Ramez N., Okamura, Ryosuke, Patel, Sandip P., Nikanjam, Mina, Lanman, Richard B., Piccioni, David E., Kato, Shumei, McHale, Michael T., Kurzrock, Razelle

“…In gynecologic cancer patients, therapy matched to ctDNA alterations (N = 33 patients) was independently associated with improved overall survival (hazard…”
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PARP Inhibitors in Epithelial Ovarian Cancer by Taylor, Kristin N, Eskander, Ramez N

“…Ovarian cancer remains the most common lethal gynecologic malignancy. The therapeutic gains with the use of traditional cytotoxic chemotherapy in advanced…”
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Early-stage multi-cancer detection using an extracellular vesicle protein-based blood test by Hinestrosa, Juan Pablo, Kurzrock, Razelle, Lewis, Jean M., Schork, Nicholas J., Schroeder, Gregor, Kamat, Ashish M., Lowy, Andrew M., Eskander, Ramez N., Perrera, Orlando, Searson, David, Rastegar, Kiarash, Hughes, Jake R., Ortiz, Victor, Clark, Iryna, Balcer, Heath I., Arakelyan, Larry, Turner, Robert, Billings, Paul R., Adler, Mark J., Lippman, Scott M., Krishnan, Rajaram

“…Background Detecting cancer at early stages significantly increases patient survival rates. Because lethal solid tumors often produce few symptoms before…”
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Immunotherapy: An Evolving Paradigm in the Treatment of Advanced Cervical Cancer by Eskander, Ramez N., MD, Tewari, Krishnansu S., MD

“…Abstract Purpose In 2014, the US Food and Drug Administration approved the first targeted agent, bevacizumab, in the treatment of advanced stage, persistent,…”
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Immunotherapy as a treatment strategy in advanced stage and recurrent endometrial cancer: review of current phase III immunotherapy clinical trials by Eskander, Ramez N., Powell, Matthew A.

“…The treatment of advanced stage, metastatic or recurrent endometrial cancer remains a clinically difficult scenario. Although combination carboplatin and…”
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Overcoming the challenges of drug development in platinum-resistant ovarian cancer by Eskander, Ramez N., Moore, Kathleen N., Monk, Bradley J., Herzog, Thomas J., Annunziata, Christina M., O’Malley, David M., Coleman, Robert L.

“…The definition of “platinum-resistant ovarian cancer” has evolved; it now also reflects cancers for which platinum treatment is no longer an option. Standard…”
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A Markov model to evaluate cost-effectiveness of antiangiogenesis therapy using bevacizumab in advanced cervical cancer by Minion, Lindsey E, Bai, Jiaru, Monk, Bradley J, Robin Keller, L, Ramez, Eskander N, Forde, Gareth K, Chan, John K, Tewari, Krishnansu S

“…Abstract Objective To evaluate the cost-effectiveness of bevacizumab in recurrent/persistent and metastatic cervical cancer using recently reported updated…”
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Cost-effective Analysis of Subcutaneous vs Sublingual Immunotherapy From the Payor’s Perspective by Hardin, Frances Mei, Eskander, Peter N., Franzese, Christine

“…Objective Compare the cost-effectiveness of subcutaneous immunotherapy (SCIT) and aqueous sublingual immunotherapy (SLIT) as treatment modalities for adult…”
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Fertility preserving options in patients with gynecologic malignancies by Eskander, Ramez N., MD, Randall, Leslie M., MD, Berman, Michael L., MD, Tewari, Krishnansu S., MD, Disaia, Philip J., MD, Bristow, Robert E., MD

“…A proportion of reproductive age women are affected by gynecologic malignancies. This patient population is faced with difficult decisions, related to their…”
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Targeting angiogenesis in advanced cervical cancer by Eskander, Ramez N., Tewari, Krishnansu S.

“…Patients with advanced stage or recurrent cervical cancer represent a population with limited chemotherapeutic options. More specifically, patients with…”
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Beyond angiogenesis blockade: targeted therapy for advanced cervical cancer by Eskander, Ramez N, Tewari, Krishnansu S

“…The global burden of advanced stage cervical cancer remains significant, particular in resource poor countries where effective screening programs are absent…”
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Energy flow and management of a hybrid wind/PV/fuel cell generation system by El-Shatter, Thanaa F., Eskander, Mona N., El-Hagry, Mohsen T.

“…In this paper, an energy system comprising three energy sources, namely PV, wind and fuel cells, is proposed. Each of the three energy sources is controlled so…”
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Novel circuit to compensate the effect of source open circuit fault in distributed generation system by Nashed, Maged N. F, Eskander, Mona N

“…In this paper a novel compensating circuit, composed of capacitors, one IGBT switch, and a diode bridge is designed and employed within a SOFC distributed…”
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Pan-cancer molecular tumor board experience with biomarker-driven precision immunotherapy by Louie, Bryan H., Kato, Shumei, Kim, Ki Hwan, Lim, Hyo Jeong, Okamura, Ryosuke, Eskander, Ramez N., Botta, Gregory, Patel, Hitendra, Lee, Suzanna, Lippman, Scott M., Sicklick, Jason K., Kurzrock, Razelle

“…Despite remarkable responses to immune checkpoint blockade (ICB) in some advanced cancers, most patients do not benefit, perhaps due to the complexity of…”
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Exploiting the therapeutic potential of the PI3K-AKT-mTOR pathway in enriched populations of gynecologic malignancies by Eskander, Ramez N, Tewari, Krishnansu S

“…Given the prevalence of phosphatase & tensin homolog mutations in histologic specimens harvested from patients with endometrial cancer, significant interest in…”
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Survey of trends in authorship assignment in gynecologic oncology: Keeping score and playing fair by Chambers, Laura M., Watson, Catherine H., Yao, Meng, Levinson, Kimberly, Alvarez, Ronald D., Eskander, Ramez N., Buechel, Megan, Michener, Chad M., Jernigan, Amelia

“…•30.6% of responding gynecologic oncologists reported assignment of authorship that did not meet ICMJE criteria.•The majority reported that ICMJE criteria were…”
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ATHENA (GOG-3020/ENGOT-ov45): a randomized, phase III trial to evaluate rucaparib as monotherapy (ATHENA-MONO) and rucaparib in combination with nivolumab (ATHENA-COMBO) as maintenance treatment following frontline platinum-based chemotherapy in ovarian cancer by Monk, Bradley J, Coleman, Robert L, Fujiwara, Keiichi, Wilson, Michelle K, Oza, Amit M, Oaknin, Ana, O'Malley, David M, Lorusso, Domenica, Westin, Shannon N, Safra, Tamar, Herzog, Thomas J, Marmé, Frederik, N Eskander, Ramez, Lin, Kevin K, Shih, Danny, Goble, Sandra, Grechko, Nikolay, Hume, Stephanie, Maloney, Lara, McNeish, Iain A, Kristeleit, Rebecca S

“…The optimal treatment strategy for women with newly diagnosed ovarian cancer has yet to be determined. Poly(ADP-ribose) polymerase (PARP) inhibitors have…”
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De-implementation and substitution of clinical care processes: stakeholder perspectives on the transition to primary human papillomavirus (HPV) testing for cervical cancer screening by Hahn, Erin E., Munoz-Plaza, Corrine, Altman, Danielle E., Hsu, Chunyi, Cannizzaro, Nancy T., Ngo-Metzger, Quyen, Wride, Patricia, Gould, Michael K., Mittman, Brian S., Hodeib, Melissa, Tewari, Krishnansu S., Ajamian, Lena H., Eskander, Ramez N., Tewari, Devansu, Chao, Chun R.

“…Abstract Background New cervical cancer screening guidelines recommend primary human papillomavirus (HPV) testing for women age 30–65 years. Healthcare…”
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Clinical trials, adaptability and the COVID-19 pandemic by Eskander, Ramez N., Pothuri, Bhavana, Randall, Leslie, O'Malley, David, Slomovitz, Brian, Moore, Kathleen, Coleman, Robert, Herzog, Thomas, Monk, Bradley J., Copeland, Larry

“…•The COVID-19 pandemic has required adaptability in the workplace.•Women health care professionals are disproportionately affected by the burdens resulting…”
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