Search Results - "Esgueva, Raquel"
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The genomic complexity of primary human prostate cancer
Published in Nature (London) (10-02-2011)“…Prostate cancer is the second most common cause of male cancer deaths in the United States. However, the full range of prostate cancer genomic alterations is…”
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TMPRSS2-ERG gene fusion prevalence and class are significantly different in prostate cancer of caucasian, african-american and japanese patients
Published in The Prostate (01-04-2011)“…BACKGROUND Prostate cancer (PCa) exhibits significant differences in prevalence and mortality among different ethnic groups. The underlying genetics is not…”
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Rearrangements of the RAF kinase pathway in prostate cancer, gastric cancer and melanoma
Published in Nature medicine (01-07-2010)“…Although recurrent gene fusions involving erythroblastosis virus E26 transformation-specific (ETS) family transcription factors are common in prostate cancer,…”
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Antibody-Based Detection of ERG Rearrangement-Positive Prostate Cancer
Published in Neoplasia (New York, N.Y.) (01-07-2010)“…TMPRSS2-ERG gene fusions occur in 50% of prostate cancers and result in the overexpression of a chimeric fusion transcript that encodes a truncated ERG…”
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Prevalence of TMPRSS2–ERG and SLC45A3–ERG gene fusions in a large prostatectomy cohort
Published in Modern pathology (01-04-2010)“…The majority of prostate cancers harbor recurrent gene fusions between the hormone-regulated TMPRSS2 and members of the ETS family of transcription factors,…”
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KLF6 and TP53 mutations are a rare event in prostate cancer: distinguishing between Taq polymerase artifacts and true mutations
Published in Modern pathology (01-12-2008)“…Krüppel-like factor 6 ( KLF6 ) has been reported to act as a tumor suppressor gene involved in the regulation of the cell cycle by activating p21 in a…”
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Fatal liver failure: molecular evidence for chronic active Epstein-Barr virus infection
Published in Annals of diagnostic pathology (01-10-2008)“…Abstract Epstein-Barr virus (EBV) infection is a benign disease, which may occasionally be fatal, particularly in children and immunocompromised patients…”
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Discovery of non-ETS gene fusions in human prostate cancer using next-generation RNA sequencing
Published in Genome research (01-01-2011)“…Half of prostate cancers harbor gene fusions between TMPRSS2 and members of the ETS transcription factor family. To date, little is known about the presence of…”
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Acute oesophageal necrosis (black oesophagus)
Published in Revista española de enfermedades digestivas (01-03-2016)“…A 54-year-old man was admitted to hospital after being found unconscious in his home. He had a history of alcoholism, multiple drug addictions, and type I…”
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FGFR3 mutations in prostate cancer: association with low-grade tumors
Published in Modern pathology (01-06-2009)“…Prostate cancer is the second cause of cancer-related death in men of the Western World. The role of FGFR3 and its abnormalities in prostate cancer are not…”
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Response to ‘TMPRSS2-ERG gene fusions are infrequent in prostatic ductal adenocarcinomas’
Published in Modern pathology (01-10-2009)Get full text
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TMPRSS2-ERG gene fusions are infrequent in prostatic ductal adenocarcinomas
Published in Modern pathology (01-10-2009)Get full text
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Acute oesophageal necrosis (black oesophagus)
Published in Revista española de enfermedades digestivas (01-03-2016)Get full text
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Next-generation prostate cancer biobanking: toward a processing protocol amenable for the International Cancer Genome Consortium
Published in Diagnostic molecular pathology (01-06-2012)“…Next-generation DNA and RNA sequencing requires intact nucleic acids from high-quality human tissue samples to better elucidate the molecular basis of cancer…”
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Abstract 2743: Accelerating the exploration of novel gene fusion events in prostate cancer
Published in Cancer research (Chicago, Ill.) (15-04-2010)“…Abstract Gene fusions are regarded as cancer defining and often proven causative for cancer development. Up to 50% of prostate cancers harbor recurrent gene…”
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Abstract 3925: Characterization of complex chromosomal aberrations in prostate cancer from whole genome sequencing
Published in Cancer research (Chicago, Ill.) (15-04-2011)“…Abstract Prostate cancer is the second most common cause of male cancer deaths in the United States, accounting for 200,000 new cases and 32,000 deaths per…”
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Antibody-Based Detection of ERG Rearrangement-Positive Prostate Cancer12
Published in Neoplasia (New York, N.Y.) (01-07-2010)“…TMPRSS2-ERG gene fusions occur in 50% of prostate cancers and result in the overexpression of a chimeric fusion transcript that encodes a truncated ERG…”
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Acute oesophageal necrosis (black oesophagus)
Published in Revista española de enfermedades digestivasGet full text
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20
Post-mortem toxicology in the diagnosis of sudden death in young and middle-aged victims
Published in European review for medical and pharmacological sciences (01-11-2019)“…We aimed to investigate the impact of the toxicological results found in cases of sudden death (SD) and to correlate the clinical, autopsy and genetic findings…”
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