Search Results - "Esfandyari, Javanshir"

The Iroquois homeobox proteins IRX3 and IRX5 have distinct roles in Wilms tumour development and human nephrogenesis by Holmquist Mengelbier, Linda, Lindell‐Munther, Simon, Yasui, Hiroaki, Jansson, Caroline, Esfandyari, Javanshir, Karlsson, Jenny, Lau, Kimberly, Hui, Chi‐chung, Bexell, Daniel, Hopyan, Sevan, Gisselsson, David

“…Wilms tumour is a paediatric malignancy with features of halted kidney development. Here, we demonstrate that the Iroquois homeobox genes IRX3 and IRX5 are…”
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Anti‐tumor effects of PIM/PI3K/mTOR triple kinase inhibitor IBL‐302 in neuroblastoma by Mohlin, Sofie, Hansson, Karin, Radke, Katarzyna, Martinez, Sonia, Blanco‐Apiricio, Carmen, Garcia‐Ruiz, Cristian, Welinder, Charlotte, Esfandyari, Javanshir, O'Neill, Michael, Pastor, Joaquin, von Stedingk, Kristoffer, Bexell, Daniel

“…The PI3K pathway is a major driver of cancer progression. However, clinical resistance to PI3K inhibition is common. IBL‐302 is a novel highly specific triple…”
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Anti‐tumor effects of PIM / PI 3K/ mTOR triple kinase inhibitor IBL ‐302 in neuroblastoma by Mohlin, Sofie, Hansson, Karin, Radke, Katarzyna, Martinez, Sonia, Blanco‐Aparicio, Carmen, Garcia‐Ruiz, Cristian, Welinder, Charlotte, Esfandyari, Javanshir, O'Neill, Michael, Pastor, Joaquin, von Stedingk, Kristoffer, Bexell, Daniel

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Anti-tumor effects of rigosertib in high-risk neuroblastoma by Radke, Katarzyna, Hansson, Karin, Sjölund, Jonas, Wolska, Magdalena, Karlsson, Jenny, Esfandyari, Javanshir, Pietras, Kristian, Aaltonen, Kristina, Gisselsson, David, Bexell, Daniel

“…•Analysis of multiple tumor types reveal neuroblastoma sensitivity to rigosertib.•Neuroblastoma 2D and 3D organoid models are sensitive to…”
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Anti‐tumor effects of PIM / PI 3K/ mTOR triple kinase inhibitor IBL ‐302 in neuroblastoma by Mohlin, Sofie, Hansson, Karin, Radke, Katarzyna, Martinez, Sonia, Blanco‐Apiricio, Carmen, Garcia‐Ruiz, Cristian, Welinder, Charlotte, Esfandyari, Javanshir, O'Neill, Michael, Pastor, Joaquin, von Stedingk, Kristoffer, Bexell, Daniel

“…The PI3K pathway is a major driver of cancer progression. However, clinical resistance to PI3K inhibition is common. IBL‐302 is a novel highly specific triple…”
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Erratum To: Anti‐tumor effects of PIM/PI3K/mTOR triple kinase inhibitor IBL‐302 in neuroblastoma by Mohlin, Sofie, Hansson, Karin, Radke, Katarzyna, Martinez, Sonia, Blanco‐Aparicio, Carmen, Garcia‐Ruiz, Cristian, Welinder, Charlotte, Esfandyari, Javanshir, O'Neill, Michael, Pastor, Joaquin, von Stedingk, Kristoffer, Bexell, Daniel

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Effects of COJEC induction on neuroblastoma patient-derived xenografts (PDX) by Manas Nunez, Adriana, Aaltonen, Kristina, Hansson, Karin, Radke, Katarzyna, Esfandyari, Javanshir, Gisselsson, David, Bexell, Daniel

“…Abstract only e21503 Background: Neuroblastoma (NB) is a solid pediatric tumor that causes 15% of childhood cancer deaths. High-risk patients have 50 to 70%…”
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Patient-Derived Xenograft Models Reveal Intratumor Heterogeneity and Temporal Stability in Neuroblastoma by Braekeveldt, Noémie, von Stedingk, Kristoffer, Fransson, Susanne, Martinez-Monleon, Angela, Lindgren, David, Axelson, Håkan, Levander, Fredrik, Willforss, Jakob, Hansson, Karin, Øra, Ingrid, Backman, Torbjörn, Börjesson, Anna, Beckman, Siv, Esfandyari, Javanshir, Berbegall, Ana P, Noguera, Rosa, Karlsson, Jenny, Koster, Jan, Martinsson, Tommy, Gisselsson, David, Påhlman, Sven, Bexell, Daniel

“…Patient-derived xenografts (PDX) and the Avatar, a single PDX mirroring an individual patient, are emerging tools in preclinical cancer research. However, the…”
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Anti‐tumor effects of PIM/PI3K/mTOR triple kinase inhibitor IBL‐302 in neuroblastoma by Mohlin, Sofie, Hansson, Karin, Radke, Katarzyna, Martinez, Sonia, Blanco‐Aparicio, Carmen, Garcia‐Ruiz, Cristian, Welinder, Charlotte, Esfandyari, Javanshir, O'Neill, Michael, Pastor, Joaquin, Stedingk, Kristoffer, Bexell, Daniel

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Clinically relevant treatment of PDX models reveals patterns of neuroblastoma chemoresistance by Mañas, Adriana, Aaltonen, Kristina, Andersson, Natalie, Hansson, Karin, Adamska, Aleksandra, Seger, Alexandra, Yasui, Hiroaki, van den Bos, Hilda, Radke, Katarzyna, Esfandyari, Javanshir, Bhave, Madhura Satish, Karlsson, Jenny, Spierings, Diana, Foijer, Floris, Gisselsson, David, Bexell, Daniel

“…Chemotherapy resistance and relapses are common in high-risk neuroblastoma (NB). Here, we developed a clinically relevant in vivo treatment protocol mimicking…”
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Abstract A011: Deciphering clonal evolution under chemotherapy in high-risk neuroblastoma using patient derived models by Andersson, Natalie, Nuñez, Adriana Mañas, Aaltonen, Kristina, Hansson, Karin, Seger, Alexandra, Radke, Katarzyna, Esfandyari, Javanshir, Bexell, Daniel, Gisselsson, David

“…This abstract is being presented as a short talk in the scientific program. A full abstract is available in the Proffered Abstracts section (PR001) of the…”
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Abstract PR001: Deciphering clonal evolution under chemotherapy in high-risk neuroblastoma using patient derived models by Andersson, Natalie, Nuñez, Adriana Mañas, Aaltonen, Kristina, Hansson, Karin, Seger, Alexandra, Radke, Katarzyna, Esfandyari, Javanshir, Bexell, Daniel, Gisselsson, David

“…Neuroblastoma is a pediatric tumor originating from the developing sympathetic nervous system, most often arising in the adrenal medulla in children below 5…”
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Abstract 3901: Modeling and deciphering COJEC resistance in high risk neuroblastoma by Mañas, Adriana, Aaltonen, Kristina, Andersson, Natalie, Hansson, Karin, Seger, Alexandra, Yasui, Hiroaki, Radke, Katarzyna, Esfandyari, Javanshir, Lindgren, David, Gisselsson, David, Bexell, Daniel

“…Neuroblastoma (NB) is a pediatric cancer of the sympathetic nervous system that accounts for 15% of childhood cancer deaths. High-risk (HR) NB tumors are…”
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