Search Results - "Eser, Pinar O"

EGFR Inhibition Enhances the Cellular Uptake and Antitumor-Activity of the HER3 Antibody-Drug Conjugate HER3-DXd by Haikala, Heidi M, Lopez, Timothy, Köhler, Jens, Eser, Pinar O, Xu, Man, Zeng, Qing, Teceno, Tyler J, Ngo, Kenneth, Zhao, Yutong, Ivanova, Elena V, Bertram, Arrien A, Leeper, Brittaney A, Chambers, Emily S, Adeni, Anika E, Taus, Luke J, Kuraguchi, Mari, Kirschmeier, Paul T, Yu, Channing, Shiose, Yoshinobu, Kamai, Yasuki, Qiu, Yang, Paweletz, Cloud P, Gokhale, Prafulla C, Jänne, Pasi A

“…Epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKI) are the standard-of-care treatment for -mutant non-small cell lung cancers (NSCLC)…”
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Bridging the Divide: Student Grand Rounds at the Interface of Basic Science and Clinical Medicine by Hollenhorst, Marie A, Braun, David A, Burtner, Christopher R, Cajigas, Iahn, Cunningham-Bussel, Amy C, Eser, Pinar Ö, Nabel, Christopher S, Tsai, Frederick D, Weeks, Lachelle D, Michel, Thomas, Yialamas, Maria A

“…PROBLEMAs biomedical research and clinical medicine become increasingly complex, physician–scientists and clinically oriented biomedical researchers play…”
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A Novel HER2-Selective Kinase Inhibitor Is Effective in HER2 Mutant and Amplified Non-Small Cell Lung Cancer by Son, Jieun, Jang, Jaebong, Beyett, Tyler S, Eum, Yoonji, Haikala, Heidi M, Verano, Alyssa, Lin, Mika, Hatcher, John M, Kwiatkowski, Nicholas P, Eser, Pinar Ö, Poitras, Michael J, Wang, Stephen, Xu, Man, Gokhale, Prafulla C, Cameron, Michael D, Eck, Michael J, Gray, Nathanael S, Jänne, Pasi A

“…In-frame insertions in exon 20 of HER2 are the most common HER2 mutations in patients with non-small cell lung cancer (NSCLC), a disease in which approved…”
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10E12Z CLA alters adipocyte differentiation and adipocyte cytokine expression and induces macrophage proliferation by Belda, Benjamin J, Thompson, Jerry T, Eser, Pinar O, Vanden Heuvel, John P

“…The trans-10, cis-12 (10e12z) conjugated linoleic acid (CLA) isomer of CLA is responsible for loss of lipid storage or adipose tissue in vitro or in vivo. This…”
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Marine- and plant-derived ω-3 fatty acids differentially regulate prostate cancer cell proliferation by ESER, PINAR O, VANDEN HEUVEL, JOHN P, ARAUJO, JOHN, THOMPSON, JERRY T

“…Fish oil contains the marine ω-3 polyunsaturated fatty acids (ω-3 PUFAs) docosahexaenoic (DHA) and eicosapentaenoic acid (EPA). The consumption of diets rich…”
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TGFβ pathway inhibition in the treatment of non-small cell lung cancer by Eser, Pınar Ö., Jänne, Pasi A.

“…Advanced non-small cell lung cancer (NSCLC) continues to be an incurable family of thoracic malignancies that is chronically managed with chemotherapy,…”
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Abstract 890: TGFâ upregulation mediates growth retardation in EGFR T790M mutant non-small cell lung cancer by Repellin, Claire E., Eser, Pinar O., Capelletti, Marzia, Shimamura, Takeshi, Ercan, Dalia, Xu, Chunxiao, Gray, Nathanael S., Wong, Kwok-Kin, Jänne, Pasi A.

“…Abstract Introduction: A subset of non-small cell lung cancer is driven by activating mutations in the epidermal growth factor receptor (EGFR). The majority of…”
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Abstract 1732: Switch to MET oncogene dependence as a novel mechanism of drug resistance in EGFR- mutant lung cancer by Eser, Pinar Ö., Paranal, Raymond M., Poitras, Michael J., Xu, Man, Wang, Stephen, Ogino, Atsuko, Choi, Jihyun, Missios, Pavlos, Haikala, Heidi M., Son, Jieun, Lin, Mika, Yanagita, Masahiko, Gokhale, Prafulla C., Daley, George Q., Jänne, Pasi A.

“…Abstract Introduction: Non-small cell lung cancers harboring sensitizing gain-of-function mutations in the epidermal growth factor receptor (EGFR) are treated…”
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