Search Results - "Eser, J."
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Desmosterol and DHCR24: Unexpected new directions for a terminal step in cholesterol synthesis
Published in Progress in lipid research (01-10-2013)“…3β-Hydroxysterol Δ24-reductase (DHCR24) catalyzes the conversion of desmosterol to cholesterol. This ultimate step of cholesterol biosynthesis appears to be…”
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Lipid metabolism and its implications for type 1 diabetes-associated cardiomyopathy
Published in Journal of molecular endocrinology (01-05-2017)“…Diabetic cardiomyopathy was first defined over four decades ago. It was observed in small post-mortem studies of diabetic patients who suffered from…”
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An integrative systems genetic analysis of mammalian lipid metabolism
Published in Nature (London) (01-03-2019)“…Dysregulation of lipid homeostasis is a precipitating event in the pathogenesis and progression of hepatosteatosis and metabolic syndrome. These conditions are…”
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Signaling regulates activity of DHCR24, the final enzyme in cholesterol synthesis[S]
Published in Journal of lipid research (01-03-2014)“…The role of signaling in regulating cholesterol homeostasis is gradually becoming more widely recognized. Here, we explored how kinases and phosphorylation…”
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The Use of L-sIDOL Transgenic Mice as a Murine Model to Study Hypercholesterolemia and Atherosclerosis
Published in Methods in molecular biology (Clifton, N.J.) (01-01-2017)“…There are many advantages to the use of mice as a model to study the regulation of cholesterol metabolism. Common models of hypercholesterolemia include…”
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Sterols regulate 3β-hydroxysterol Δ24-reductase (DHCR24) via dual sterol regulatory elements: Cooperative induction of key enzymes in lipid synthesis by Sterol Regulatory Element Binding Proteins
Published in Biochimica et biophysica acta (01-10-2012)“…3β-Hydroxysterol Δ24-reductase (DHCR24) catalyzes a final step in cholesterol synthesis, and has been ascribed diverse functions, such as being anti-apoptotic…”
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DHCR24 associates strongly with the endoplasmic reticulum beyond predicted membrane domains: implications for the activities of this multi-functional enzyme
Published in Bioscience reports (01-04-2014)“…Cholesterol synthesis occurs in the ER (endoplasmic reticulum), where most of the cholesterogenic machinery resides. As membrane-bound proteins, their topology…”
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The endogenous regulator 24(S),25-epoxycholesterol inhibits cholesterol synthesis at DHCR24 (Seladin-1)
Published in Biochimica et biophysica acta (01-09-2012)“…The oxysterol 24(S),25-epoxycholesterol (24,25EC) can affect cholesterol metabolism at multiple points. Previously, we proposed that 24,25EC has an especially…”
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ELVES Measurements in the “UV Atmosphere” (Mini-EUSO) Experiment Onboard the ISS and Their Reconstruction
Published in Cosmic research (2024)“…More than three dozen submillisecond events of ELVES type (“elves”), which are the result of the interaction of the front of an electromagnetic pulse from a…”
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Integration, qualification, and launch of the Mini-EUSO telescope on board the ISS
Published in Atti della Accademia nazionale dei Lincei. Rendiconti Lincei. Scienze fisiche e naturali (2023)“…Mini-EUSO is a high-sensitivity imaging telescope that observes the Earth from the ISS in the near ultraviolet band (290 ÷ 430 nm), through the nadir-facing,…”
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Cloud distribution evaluated by the WRF model during the EUSO-SPB1 flight
Published in EPJ Web of conferences (2019)“…EUSO-SPB1 was a balloon-borne mission of the JEM-EUSO (Joint Experiment Missions for Extreme Universe Space Observatory) Program aiming at the ultra-high…”
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The Detection of UHECRs with the EUSO-TA Telescope
Published in EPJ Web of Conferences (2019)“…EUSO-TA is a cosmic ray detector developed by the JEM-EUSO (Joint Experiment Missions for Extreme Universe Space Observatory) Collaboration, observing during…”
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Performance results of the trigger logic implemented in EUSO-SPB
Published in Nuclear instruments & methods in physics research. Section A, Accelerators, spectrometers, detectors and associated equipment (21-08-2019)“…EUSO-SPB (Extreme Universe Space Observatory-Super Pressure Balloon) was the first mission of the JEM-EUSO program which implemented the First Level Trigger…”
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Towards a better recycling of lithium‐ion batteries – Removal and recovery of electrolyte solvents from shredded cells
Published in Chemie ingenieur technik (01-09-2022)Get full text
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Untersuchungen zum Stofftransport bei der Intensivtrocknung von Komponenten für Li‐Ionen‐Batterien
Published in Chemie ingenieur technik (01-09-2018)Get full text
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EUSO-SPB2 Fluorescence Telescope trigger test within the EUSO@TurLab Project
Published in Nuclear instruments & methods in physics research. Section A, Accelerators, spectrometers, detectors and associated equipment (26-10-2022)“…The second generation Extreme Universe Space Observatory on a Super-Pressure Balloon (EUSO-SPB2) mission is on track to be approved by NASA for a long duration…”
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Observation of night-time emissions of the Earth in the near UV range from the International Space Station with the Mini-EUSO detector
Published in Remote sensing of environment (01-01-2023)“…Mini-EUSO (Multiwavelength Imaging New Instrument for the Extreme Universe Space Observatory) is a telescope observing the Earth from the International Space…”
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EUSO-SPB2 Fluorescence Telescope trigger test within the EUSO@TurLab Project
Published in Nuclear instruments & methods in physics research. Section A, Accelerators, spectrometers, detectors and associated equipment (01-01-2023)“…The second generation Extreme Universe Space Observatory on a Super-Pressure Balloon (EUSO-SPB2) mission is on track to be approved by NASA for a long duration…”
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Detection limits and trigger rates for ultra-high energy cosmic ray detection with the EUSO-TA ground-based fluorescence telescope
Published in Astroparticle physics (01-11-2024)“…EUSO-TA is a ground-based fluorescence telescope built to validate the design of ultra-high energy cosmic ray fluorescence detectors to be operated in space…”
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Ultra high energy cosmic rays The intersection of the Cosmic and Energy Frontiers
Published in Astroparticle physics (15-11-2022)“…The present white paper is submitted as part of the "Snowmass" process to help inform the long-term plans of the United States Department of Energy and the…”
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