Search Results - "Eser, D"
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Neuroactive steroids in affective disorders: target for novel antidepressant or anxiolytic drugs?
Published in Neuroscience (15-09-2011)“…Abstract In the past decades considerable evidence has emerged that so-called neuroactive steroids do not only act as transcriptional factors in the regulation…”
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2
SNP and haplotype analysis of a novel tryptophan hydroxylase isoform (TPH2) gene provide evidence for association with major depression
Published in Molecular psychiatry (01-11-2004)“…Tryptophan hydroxylase (TPH), being the rate-limiting enzyme in the biosynthesis of serotonin plays a major role as candidate gene in several psychiatric…”
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3
Neuroactive steroids and affective disorders
Published in Pharmacology, biochemistry and behavior (01-08-2006)“…Neuroactive steroids modulate neurotransmission through modulation of specific neurotransmitter receptors such as γ-aminobutyric acid type A (GABA A)…”
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4
Polymorphisms in the angiotensin-converting enzyme gene are associated with unipolar depression, ACE activity and hypercortisolism
Published in Molecular psychiatry (01-11-2006)“…Angiotensin-converting enzyme (ACE) is assumed to influence the activity of the hypothalamic-pituitary-adrenocortical (HPA) system, which shows hyperactivity…”
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5
Brain-derived neurotrophic factor Val66Met polymorphism and dexamethasone/CRH test results in depressed patients
Published in Psychoneuroendocrinology (01-09-2006)“…Data suggest that both neurotrophic and hypothalamic–pituitary–adrenocortical (HPA) systems are involved in the pathophysiology of depression. The aim of the…”
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6
Influence of mirtazapine on plasma concentrations of neuroactive steroids in major depression and on 3α-hydroxysteroid dehydrogenase activity
Published in Molecular psychiatry (01-03-2006)“…Concentrations of 3α-reduced neuroactive steroids are altered in depression and normalize after antidepressant pharmacotherapy with selective serotonin…”
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7
Effects of the GABA-reuptake inhibitor tiagabine on panic and anxiety in patients with panic disorder
Published in Pharmacopsychiatry (01-11-2009)“…There is evidence that a decreased GABAergic tone plays a role in the pathophysiology of panic disorder (PD). Selective GABAergic treatment has been suggested…”
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8
Effects of Alprazolam on Cholecystokinin-Tetrapeptide-Induced Panic and Hypothalamic-Pituitary-Adrenal-Axis Activity: A Placebo-Controlled Study
Published in Neuropsychopharmacology (01-05-2003)“…Cholecystokinin-tetrapeptide (CCK-4) induces panic attacks both in patients with panic disorder (PD) and healthy volunteers. It has been shown that panic…”
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9
Independent component analysis applied to pharmacological magnetic resonance imaging (phMRI): new insights into the functional networks underlying panic attacks as induced by CCK-4
Published in Current pharmaceutical design (01-11-2008)“…Pharmacological magnetic resonance imaging (phMRI) is a method to study effects of psychopharmacological agents on neural activation. Changes of the blood…”
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10
Neuroactive steroids as modulators of depression and anxiety
Published in Neuroscience (01-01-2006)“…Certain neuroactive steroids modulate ligand-gated ion channels via non-genomic mechanisms. Especially 3α-reduced pregnane steroids are potent positive…”
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Journal Article Conference Proceeding -
11
Impact of gene-gender effects of adrenergic polymorphisms on hypothalamic-pituitary-adrenal axis activity in depressed patients
Published in Neuropsychobiology (01-01-2008)“…There is overwhelming evidence that activation of the hypothalamic-pituitary-adrenal (HPA) system plays a major role in depression and cardiovascular disease…”
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12
The effects of alprazolam on brain activity in CCK-4-induced panic attacks
Published in NeuroImage (Orlando, Fla.) (01-07-2009)“…Cholecystokinine-4 (CCK-4) can be used to induce panic attacks experimentally and corrresponding fMRI activations are found in a couple of regions including…”
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13
P02-09 - Major depression, cardiovascular risk factors and the Omega-3 index
Published in European psychiatry (2011)“…Introduction Cardiovascular disease (CVD) and major depressive disorders (MDD) are frequent diseases worldwide with a high comorbidity rate. Omega-3 fatty…”
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14
Neuroactive steroids in depression and anxiety disorders: clinical studies
Published in Neuroendocrinology (01-01-2006)“…Certain neuroactive steroids modulate ligand-gated ion channels via non-genomic mechanisms. Especially 3alpha-reduced pregnane steroids are potent positive…”
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Journal Article -
15
Effects of experimentally induced panic attacks on neuroimmunological markers
Published in Journal of Neural Transmission (01-06-2009)“…Since little is known concerning regulation of immunological parameters in rapid changing psychiatric states like panic attacks, we measured cytokines at…”
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Journal Article -
16
PW01-44 - Impact of glyoxalase-1 mRNA expression on CCK-4 induced anxiety
Published in European psychiatry (2010)“…Objectives There is evidence that the antioxidant enzyme glyoxalase-1 (Glx-1) may play a role in anxiety-related behaviour. However, discordant findings…”
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17
PW01-262 - Influence of age on effectiveness and tolerability of electroconvulsive therapy
Published in European psychiatry (2010)“…Introduction The effectiveness of electroconvulsive therapy (ECT) in pharmacotherapy resistant major depression and schizophrenia has been shown for all age…”
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18
Anticonvulsants in the treatment of anxiety--an alternative treatment option?
Published in Nervenarzt (01-11-2007)“…According to epidemiological studies anxiety disorders are among the most frequent psychiatric disorders. Depending on the diagnosis and severity, both…”
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19
Core symptoms of depression. Effectiveness of antidepressant therapy
Published in Nervenarzt (01-05-2009)“…Core symptoms of depression are a combination of psychological and somatic symptoms, often associated with psychomotor and cognitive disturbances. The…”
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Neuroactive steroids are not affected by panic induction with 50 μg cholecystokinin-tetrapeptide (CCK-4) in healthy volunteers
Published in Journal of psychiatric research (01-03-2004)Get full text
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