Search Results - "Escubedo, E."

Role of amino terminal substitutions in the pharmacological, rewarding and psychostimulant profiles of novel synthetic cathinones by Duart-Castells, L., Nadal-Gratacós, N., Muralter, M., Puster, B., Berzosa, X., Estrada-Tejedor, R., Niello, M., Bhat, S., Pubill, D., Camarasa, J., Sitte, H.H., Escubedo, E., López-Arnau, R.

“…The emergence of new synthetic cathinones continues to be a matter of public health concern. In fact, they are quickly replaced by new structurally related…”
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Mephedrone pharmacokinetics after intravenous and oral administration in rats: relation to pharmacodynamics by Martínez-Clemente, J., López-Arnau, R., Carbó, M., Pubill, D., Camarasa, J., Escubedo, E.

“…Rationale Mephedrone (4-methylmethcathinone) is a still poorly known drug of abuse, alternative to ecstasy or cocaine. Objective The major aims were to…”
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Exposure of adolescent mice to 3,4‐methylenedioxypyrovalerone increases the psychostimulant, rewarding and reinforcing effects of cocaine in adulthood by López‐Arnau, R, Luján, M A, Duart‐Castells, L, Pubill, D, Camarasa, J, Valverde, O, Escubedo, E

“…Background and Purpose 3,4‐Methylenedioxypyrovalerone (MDPV) is a synthetic cathinone with powerful psychostimulant effects. It selectively inhibits the…”
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Adaptive Plasticity in the Hippocampus of Young Mice Intermittently Exposed to MDMA Could Be the Origin of Memory Deficits by Abad, S., Camarasa, J., Pubill, D., Camins, A., Escubedo, E.

“…(±)3,4-Methylenedioxymethamphetamine (MDMA) is a relatively selective dopaminergic neurotoxin in mice. This study was designed to evaluate whether MDMA…”
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Neuroadaptive changes and behavioral effects after a sensitization regime of MDPV by Duart-Castells, L., López-Arnau, R., Buenrostro-Jáuregui, M., Muñoz-Villegas, P., Valverde, O., Camarasa, J., Pubill, D., Escubedo, E.

“…3,4-methylenedioxypyrovalerone (MDPV) is a synthetic cathinone with cocaine-like properties. In a previous work, we exposed adolescent mice to MDPV, finding…”
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7,8-Dihydroxyflavone blocks the development of behavioral sensitization to MDPV, but not to cocaine: Differential role of the BDNF-TrkB pathway by Duart-Castells, L., López-Arnau, R., Vizcaíno, S., Camarasa, J., Pubill, D., Escubedo, E.

“…[Display omitted] 3,4-Methylenedioxypyrovalerone (MDPV) acts as a dopamine transporter blocker and exerts powerful psychostimulant effects. In this study we…”
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Memantine protects against amphetamine derivatives-induced neurotoxic damage in rodents by Chipana, C., Torres, I., Camarasa, J., Pubill, D., Escubedo, E.

“…We hypothesize that 3,4-methylenedioxymethamphetamine (MDMA) and methamphetamine (METH) interact with alpha-7 nicotinic receptors (nAChR). Here we examine…”
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The combination of MDPV and ethanol results in decreased cathinone and increased alcohol levels. Study of such pharmacological interaction by López-Arnau, R., Buenrostro-Jáuregui, M., Muñoz-Villegas, P., Rodríguez-Morató, J., Ciudad-Roberts, A., Duart, L., Camarasa, J., De la Torre, R., Pubill, D., Escubedo, E.

“…Methylenedioxypyrovalerone (MDPV) is a new psychostimulant cathinone acting as a selective dopamine transporter blocker. Due to the concomitant consumption of…”
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Comparative neurochemical profile of 3,4-methylenedioxymethamphetamine and its metabolite alpha-methyldopamine on key targets of MDMA neurotoxicity by Escubedo, E., Abad, S., Torres, I., Camarasa, J., Pubill, D.

“…▶ Methyldopamine constitutes the major first line of metabolites from MDMA and MDA. ▶ Methyldopamine induces a persistent change of the dopamine transporter…”
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Memantine prevents MDMA-induced neurotoxicity by Chipana, C., Camarasa, J., Pubill, D., Escubedo, E.

“…MDMA (ecstasy) is an illicit drug causing long-term neurotoxicity. Previous studies demonstrated the interaction of MDMA with alpha-7 nicotinic acetylcholine…”
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Erratum to: Mephedrone pharmacokinetics after intravenous and oral administration in rats: relation to pharmacodynamics by Martínez-Clemente, J., López-Arnau, R., Carbó, M., Pubill, D., Camarasa, J., Escubedo, E.

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Protection against MDMA-induced dopaminergic neurotoxicity in mice by methyllycaconitine: Involvement of nicotinic receptors by Chipana, C., Camarasa, J., Pubill, D., Escubedo, E.

“…Methylenedioxymethamphetamine (MDMA) is a relatively selective dopaminergic neurotoxin in mice. Previous studies demonstrated the participation of α-7…”
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Different oxidative profile and nicotinic receptor interaction of amphetamine and 3,4-methylenedioxy-methamphetamine by Chipana, C., García-Ratés, S., Camarasa, J., Pubill, D., Escubedo, E.

“…d-Amphetamine (AMPH) and MDMA increased intracellular production of reactive oxygen species (ROS) in isolated mouse striatal synaptosomes. MDMA showed a…”
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Involvement of nicotinic receptors in methamphetamine- and MDMA-induced neurotoxicity: pharmacological implications by Escubedo, E, Camarasa, J, Chipana, C, García-Ratés, S, Pubill, D

“…During the last years, we have focused on the study of the neurotoxic effects of 3,4-methylenedioxymethamphetamine (MDMA) and methamphetamine (METH) on the…”
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Depression-like behavior is dependent on age in male SAMP8 mice by Pérez-Cáceres, D., Ciudad-Roberts, A., Rodrigo, M. T., Pubill, D., Camins, A., Camarasa, J., Escubedo, E., Pallàs, M.

“…Aging is associated with an increased risk of depression in humans. To elucidate the underlying mechanisms of depression and its dependence on aging, here we…”
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C-phycocyanin protects cerebellar granule cells from low potassium/serum deprivation-induced apoptosis by Rimbau, V, Camins, A, Pubill, D, Sureda, F X, Romay, C, González, R, Jiménez, A, Escubedo, E, Camarasa, J, Pallàs, M

“…We tested the potential cytoprotective role of C-phycocyanin in rat cerebellar granule cell cultures. Cell death was induced by potassium and serum (K/S)…”
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3-amino thioacridone, a selective cyclin-dependent kinase 4 inhibitor, attenuates kainic acid-induced apoptosis in neurons by Verdaguer, E, Jordà, E.G, Canudas, A.M, Jiménez, A, Sureda, F.X, Rimbau, V, Pubill, D, Escubedo, E, Camarasa, J, Pallàs, M, Camins, A

“…The mechanisms underlying selective neuronal cell death in kainic acid-mediated neurodegeneration are not fully understood. We have recently demonstrated that…”
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Flow cytometric study of mitochondrial dysfunction after AMPA receptor activation by Camins, A., Gabriel, C., Aguirre, L., Sureda, F.X., Pallàs, M., Escubedo, E., Camarasa, J.

“…The effect of AMPA‐receptor stimulation on MMP and on the concentration of intracellular calcium ([Ca2+]i) was studied in dissociated CGC from rat pups, by…”
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Effect of 1-methyl-4-phenylpyridinium (MPP+) on mitochondrial membrane potential in cerebellar neurons : interaction with the NMDA receptor by CAMINS, A, SUREDA, F. X, GABRIEL, C, PALLAS, M, ESCUBEDO, E, CAMARASA, J

“…The effect of MPP+, a dopaminergic neurotoxin, in mitochondrial membrane potential was investigated in dissociated cerebellar granule cells using rhodamine 123…”
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Characterization of nitrobenzylthioinosine binding sites in the mitochondrial fraction of rat testis by Camins, A., Jimenez, A., Sureda, F.X., Pallàs, M., Escubedo, E., Camarasa, J.

“…The presence of [ 3H] NBMPR binding sites in the mitochondrial fraction of rat testis is described. The disssociation constant (K D) from saturation studies…”
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