Search Results - "Escolà‐Gil, Joan Carles"

Human hepatic lipase overexpression in mice induces hepatic steatosis and obesity through promoting hepatic lipogenesis and white adipose tissue lipolysis and fatty acid uptake by Cedó, Lídia, Santos, David, Roglans, Núria, Julve, Josep, Pallarès, Victor, Rivas-Urbina, Andrea, Llorente-Cortes, Vicenta, Laguna, Joan Carles, Blanco-Vaca, Francisco, Escolà-Gil, Joan Carles

“…Human hepatic lipase (hHL) is mainly localized on the hepatocyte cell surface where it hydrolyzes lipids from remnant lipoproteins and high density…”
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Human Apolipoprotein A-II Determines Plasma Triglycerides by Regulating Lipoprotein Lipase Activity and High-Density Lipoprotein Proteome by Julve, Josep, Escolà-Gil, Joan Carles, Rotllan, Noemi, Fiévet, Catherine, Vallez, Emmanuelle, de la Torre, Carolina, Ribas, Vicent, Sloan, John H, Blanco-Vaca, Francisco

“…INTRODUCTION—Apolipoprotein (apo) A-II is the second most abundant high-density lipoprotein (HDL) apolipoprotein. We assessed the mechanism involved in the…”
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Administration of CORM-2 inhibits diabetic neuropathy but does not reduce dyslipidemia in diabetic mice by Méndez-Lara, Karen Alejandra, Santos, David, Farré, Núria, Ruiz-Nogales, Sheila, Leánez, Sergi, Sánchez-Quesada, José Luis, Zapico, Edgar, Lerma, Enrique, Escolà-Gil, Joan Carles, Blanco-Vaca, Francisco, Martín-Campos, Jesús María, Julve, Josep, Pol, Olga

“…The antinociceptive effects of the carbon monoxide-releasing molecule tricarbonyldichlororuthenium (II) dimer (CORM-2) during chronic pain are well documented,…”
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Cyclooxygenase 2 Inhibition Exacerbates Palmitate-Induced Inflammation and Insulin Resistance in Skeletal Muscle Cells by Coll, Teresa, Palomer, Xavier, Blanco-Vaca, Francisco, Escolà-Gil, Joan Carles, Sánchez, Rosa M, Laguna, Juan C, Vázquez-Carrera, Manuel

“…Palmitate-induced inflammation is involved in the development of insulin resistance in skeletal muscle cells. Here we evaluated the effect of the saturated…”
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Trimethylamine N -Oxide: A Link among Diet, Gut Microbiota, Gene Regulation of Liver and Intestine Cholesterol Homeostasis and HDL Function by Canyelles, Marina, Tondo, Mireia, Cedó, Lídia, Farràs, Marta, Escolà-Gil, Joan Carles, Blanco-Vaca, Francisco

“…Recent evidence, including massive gene-expression analysis and a wide-variety of other multi-omics approaches, demonstrates an interplay between gut…”
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Phytosterol‐mediated inhibition of intestinal cholesterol absorption in mice is independent of liver X receptor by Cedó, Lídia, Santos, David, Ludwig, Iziar A., Silvennoinen, Reija, García‐León, Annabel, Kaipiainen, Leena, Carbó, José M., Valledor, Annabel F., Gylling, Helena, Motilva, Maria‐José, Kovanen, Petri T., Lee‐Rueckert, Miriam, Blanco‐Vaca, Francisco, Escolà‐Gil, Joan Carles

“…Scope Previous studies have proposed that phytosterols activate liver X receptors (LXR) in the intestine, thereby reducing intestinal cholesterol absorption…”
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Gut Microbiota-Derived TMAO: A Causal Factor Promoting Atherosclerotic Cardiovascular Disease? by Canyelles, Marina, Borràs, Carla, Rotllan, Noemí, Tondo, Mireia, Escolà-Gil, Joan Carles, Blanco-Vaca, Francisco

“…Trimethylamine-N-oxide (TMAO) is the main diet-induced metabolite produced by the gut microbiota, and it is mainly eliminated through renal excretion. TMAO has…”
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SUCNR1 signaling in adipocytes controls energy metabolism by modulating circadian clock and leptin expression by Villanueva-Carmona, Teresa, Cedó, Lídia, Madeira, Ana, Ceperuelo-Mallafré, Victòria, Rodríguez-Peña, M.-Mar, Núñez-Roa, Catalina, Maymó- Masip, Elsa, Repollés-de-Dalmau, Maria, Badia, Joan, Keiran, Noelia, Mirasierra, Mercedes, Pimenta-Lopes, Carolina, Sabadell-Basallote, Joan, Bosch, Ramón, Caubet, Laura, Escolà- Gil, Joan Carles, Fernández-Real, José-Manuel, Vilarrasa, Nuria, Ventura, Francesc, Vallejo, Mario, Vendrell, Joan, Fernández-Veledo, Sonia

“…Adipose tissue modulates energy homeostasis by secreting leptin, but little is known about the factors governing leptin production. We show that succinate,…”
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Phytosterols and Health: Current Status and Future Perspectives by Escolà-Gil, Joan Carles

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Macrophage Cholesterol Efflux Downregulation Is Not Associated with Abdominal Aortic Aneurysm (AAA) Progression by Canyelles, Marina, Tondo, Mireia, Lindholt, Jes S, Santos, David, Fernández-Alonso, Irati, de Gonzalo-Calvo, David, Blanco-Colio, Luis Miguel, Escolà-Gil, Joan Carles, Martín-Ventura, José Luís, Blanco-Vaca, Francisco

“…Recent studies have raised the possibility of a role for lipoproteins, including high-density lipoprotein cholesterol (HDLc), in abdominal aortic aneurysm…”
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Epigenetic Regulation by microRNAs in Hyperhomocysteinemia-Accelerated Atherosclerosis by Griñán, Raquel, Escolà-Gil, Joan Carles, Julve, Josep, Benítez, Sonia, Rotllan, Noemí

“…Increased serum levels of homocysteine (Hcy) is a risk factor for cardiovascular disease and is specifically linked to various diseases of the vasculature such…”
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HDL-like-Mediated Cell Cholesterol Trafficking in the Central Nervous System and Alzheimer’s Disease Pathogenesis by Borràs, Carla, Mercer, Aina, Sirisi, Sònia, Alcolea, Daniel, Escolà-Gil, Joan Carles, Blanco-Vaca, Francisco, Tondo, Mireia

“…The main aim of this work is to review the mechanisms via which high-density lipoprotein (HDL)-mediated cholesterol trafficking through the central nervous…”
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Pharmacologic Activation of LXR Alters the Expression Profile of Tumor-Associated Macrophages and the Abundance of Regulatory T Cells in the Tumor Microenvironment by Carbó, José M, León, Theresa E, Font-Díaz, Joan, De la Rosa, Juan Vladimir, Castrillo, Antonio, Picard, Felix R, Staudenraus, Daniel, Huber, Magdalena, Cedó, Lídia, Escolà-Gil, Joan Carles, Campos, Lucía, Bakiri, Latifa, Wagner, Erwin F, Caelles, Carme, Stratmann, Thomas, Van Ginderachter, Jo A, Valledor, Annabel F

“…Liver X receptors (LXR) are transcription factors from the nuclear receptor family that are activated by oxysterols and synthetic high-affinity agonists. In…”
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Detrimental Effect of Hypercholesterolemia on High-Density Lipoprotein Particle Remodeling in Pigs by Padró, Teresa, Cubedo, Judit, Camino, Sandra, Béjar, Maria Teresa, Ben-Aicha, Soumaya, Mendieta, Guiomar, Escolà-Gil, Joan Carles, Escate, Rafael, Gutiérrez, Manuel, Casani, Laura, Badimon, Lina, Vilahur, Gemma

“…Beneficial effects of high-density lipoproteins (HDL) seem altered in patients with symptomatic cardiovascular disease. We recently demonstrated in a swine…”
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Inhibitory Effects of LRP1-Based Immunotherapy on Cardiac Extracellular Matrix Biophysical Alterations Induced by Hypercholesterolemia by Samouillan, Valerie, Garcia, Eduardo, Benitez-Amaro, Aleyda, La Chica Lhoëst, Maria Teresa, Dandurand, Jany, Actis Dato, Virginia, Guerra, Jose Maria, Escolà-Gil, Joan Carles, Chiabrando, Gustavo, Enrich, Carlos, Llorente-Cortes, Vicenta

“…The accumulation of lipids in cardiomyocytes contributes to cardiac dysfunction. The specific blockage of cardiomyocyte cholesteryl ester (CE) loading by…”
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Effects of Virgin Olive Oil and Phenol-Enriched Virgin Olive Oils on Lipoprotein Atherogenicity by Farràs, Marta, Canyelles, Marina, Fitó, Montserrat, Escolà-Gil, Joan Carles

“…The atherogenicity of low-density lipoprotein (LDL) and triglyceride-rich lipoproteins (TRLs) may be more significant than LDL cholesterol levels. Clinical…”
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Cross-Talk between Inflammatory Mediators and the Epithelial Mesenchymal Transition Process in the Development of Thyroid Carcinoma by Revilla, Giovanna, Corcoy, Rosa, Moral, Antonio, Escolà-Gil, Joan Carles, Mato, Eugenia

“…There is strong association between inflammatory processes and their main metabolic mediators, such as leptin, adiponectin secretion, and low/high-density…”
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The Cholesterol Content of Western Diets Plays a Major Role in the Paradoxical Increase in High-Density Lipoprotein Cholesterol and Upregulates the Macrophage Reverse Cholesterol Transport Pathway by Escolà-Gil, Joan Carles, Llaverias, Gemma, Julve, Josep, Jauhiainen, Matti, Méndez-González, Jesús, Blanco-Vaca, Francisco

“…OBJECTIVE—A high–saturated fatty acid– and cholesterol-containing (HFHC) diet is considered to be a major risk factor for cardiovascular disease. The present…”
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Low-Density Lipoprotein Receptor Is a Key Driver of Aggressiveness in Thyroid Tumor Cells by Revilla, Giovanna, Ruiz-Auladell, Lara, Vallverdú, Núria Fucui, Santamaría, Paula, Moral, Antonio, Pérez, José Ignacio, Li, Changda, Fuste, Victoria, Lerma, Enrique, Corcoy, Rosa, Pitoia, Fabián, Escolà-Gil, Joan Carles, Mato, Eugènia

“…We previously described the role of low-density lipoprotein (LDL) in aggressiveness in papillary thyroid cancer (PTC). Moreover, the MAPK signaling pathway in…”
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Malondialdehyde-modified HDL particles elicit a specific IgG response in abdominal aortic aneurysm by Rodríguez-Carrio, Javier, Cerro-Pardo, Isabel, Lindholt, Jes S., Bonzon-Kulichenko, Elena, Martínez-López, Diego, Roldán-Montero, Raquel, Escolà-Gil, Joan-Carles, Michel, Jean-Baptiste, Blanco-Colio, Luis Miguel, Vázquez, Jesús, Suárez, Ana, Martín-Ventura, José Luis

“…High Density Lipoprotein (HDL) plays a protective role in abdominal aortic aneurysm (AAA); however, recent findings suggest that oxidative modifications could…”
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