Search Results - "Eschle, B K"

Antagonism of metabotropic glutamate receptor 4 receptors by (RS)-α-cyclopropyl-4-phosphonophenylglycine alters the taste of amino acids in rats by Eschle, B.K, Eddy, M.C, Delay, E.R

“…Abstract T1R1/T1R3, taste-metabotropic glutamate receptor (mGluR) 4 and other taste receptors have been implicated in umami taste perceptionT1R1/T1R3 has also…”
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Comparison of l -monosodium glutamate and l -amino acid taste in rats by Delay, E.R, Mitzelfelt, J.D, Westburg, Ä.M, Gross, N, Duran, B.L, Eschle, B.K

“…Abstract T1R2/T1R3 heterodimers are selectively responsive to sweet substances whereas T1R1/T1R3 receptors are selective for umami substances, represented by…”
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Behavioral comparison of sucrose and l -2-amino-4-phosphonobutyrate ( l -AP4) tastes in rats: Does l -AP4 have a sweet taste? by Eschle, B.K, Eddy, M.C, Spang, C.H, Delay, E.R

“…Abstract Even though it is generally thought that umami stimuli such as monosodium glutamate (MSG) and sweet stimuli such as sucrose are detected by different…”
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The selective phosphodiesterase 9 (PDE9) inhibitor PF-04447943 (6-[(3S,4S)-4-methyl-1-(pyrimidin-2-ylmethyl)pyrrolidin-3-yl]-1-(tetrahydro-2H-pyran-4-yl)-1,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one) enhances synaptic plasticity and cognitive function in rodents by Hutson, P H, Finger, E N, Magliaro, B C, Smith, S M, Converso, A, Sanderson, P E, Mullins, D, Hyde, L A, Eschle, B K, Turnbull, Z, Sloan, H, Guzzi, M, Zhang, X, Wang, A, Rindgen, D, Mazzola, R, Vivian, J A, Eddins, D, Uslaner, J M, Bednar, R, Gambone, C, Le-Mair, W, Marino, M J, Sachs, N, Xu, G, Parmentier-Batteur, S

“…Inhibition of phosphodiesterase 9 (PDE9) has been reported to enhance rodent cognitive function and may represent a potential novel approach to improving…”
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Antagonism of metabotropic glutamate receptor 4 receptors by (RS)-a-cyclopropyl-4-phosphonophenylglycine alters the taste of amino acids in rats by Eschle, B K, Eddy, M C, Delay, E R

“…T1R1/T1R3, taste-metabotropic glutamate receptor (mGluR) 4 and other taste receptors have been implicated in umami taste perceptionT1R1 /T1R3 has also been…”
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Conditioned Aversion Study of Sucrose and SC45647 Taste in TRPM5 Knockout Mice by Eddy, Meghan C, Eschle, Benjamin K, Peterson, Darlene, Lauras, Nathan, Margolskee, Robert F, Delay, Eugene R

“…Previously, published studies have reported mixed results regarding the role of the TRPM5 cation channel in signaling sweet taste by taste sensory cells. Some…”
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The selective phosphodiesterase 9 (PDE9) inhibitor PF-04447943 (6-[(3S,4S)-4-methyl-1-(pyrimidin-2-ylmethyl)pyrrolidin-3-yl]-1-(t e trahydro-2H-pyran-4-yl)-1,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4- o n e) enhances synaptic plasticity and cognitive function in rodents by Hutson, PH, Finger, EN, Magliaro, B C, Smith, S M, Converso, A, Sanderson, P E, Mullins, D, Hyde, LA, Eschle, B K, Turnbull, Z, Sloan, H, Guzzi, M, Zhang, X, Wang, A, Rindgen, D, Mazzola, R, Vivian, JA, Eddins, D, Uslaner, J M, Bednar, R, Gambone, C, Le-Mair, W, Marino, MJ, Sachs, N, Xu, G, Parmentier-Batteur, S

“…Inhibition of phosphodiesterase 9 (PDE9) has been reported to enhance rodent cognitive function and may represent a potential novel approach to improving…”
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Double P2X2/P2X3 Purinergic Receptor Knockout Mice Do Not Taste NaCl or the Artificial Sweetener SC45647 by Eddy, Meghan C., Eschle, Benjamin K., Barrows, Jennell, Hallock, Robert M., Finger, Thomas E., Delay, Eugene R.

“…The P2X ionotropic purinergic receptors, P2X2 and P2X3, are essential for transmission of taste information from taste buds to the gustatory nerves. Mice…”
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