Search Results - "Esch, Robert E."

Fungal raw materials used to produce allergen extracts by Esch, Robert E., PhD, Codina, Rosa, PhD

“…Abstract Objective To review the topic of fungal raw materials used for the production of allergen extracts and the associated challenges and highlight…”
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Randomized, double-blind, placebo-controlled trial of standardized ragweed sublingual-liquid immunotherapy for allergic rhinoconjunctivitis by Creticos, Peter S., MD, Esch, Robert E., PhD, Couroux, Peter, MD, Gentile, Deborah, MD, D'Angelo, Pina, MSc, Whitlow, Brad, BS, Alexander, Michael, MD, Coyne, Terrance C., MD

“…Background Sublingual immunotherapy with liquid extracts provides an appealing alternative to subcutaneous immunotherapy for the treatment of allergic…”
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Mite allergen extracts and clinical practice by Carnés, Jerónimo, PhD, Iraola, Víctor, PhD, Cho, Seong H., MD, Esch, Robert E., PhD

“…Abstract Objective To provide physicians, researchers, and other interested health care professionals with information about how mite source materials and…”
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Allergen immunotherapy: What can and cannot be mixed? by Esch, Robert E., PhD

“…In some cases, increasing the glycerin concentration to 50% significantly increased the stability of the mixture and its shelf-life, but the results are not…”
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Manufacturing and standardizing fungal allergen products by Esch, Robert E

“…The importance of fungal allergen products in the practice of clinical allergy is frequently underestimated. A wide variety of fungal species have been…”
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Allergen immunotherapy practice in the United States: guidelines, measures, and outcomes by Cox, Linda, MD, Esch, Robert E., PhD, Corbett, Mark, MD, Hankin, Cheryl, PhD, Nelson, Michael, MD, PhD, Plunkett, Greg, PhD

“…To discuss recent issues pertinent to allergen immunotherapy practice in the United States. Allergen extract preparation guidelines, updated allergen…”
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Sublingual immunotherapy in patients with allergic rhinoconjunctivitis caused by ragweed pollen by Skoner, David, MD, Gentile, Deborah, MD, Bush, Robert, MD, Fasano, Mary Beth, MD, McLaughlin, Anne, MD, Esch, Robert E., PhD

“…Background Specific allergen immunotherapy is most often delivered subcutaneously, but sublingual immunotherapy may confer greater benefit in terms of…”
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Evaluation and Interpretation of the Purity of Pollen Used to Manufacture Allergen Extracts by Codina, Rosa, PhD, FAAAAI, Crenshaw, Rodger C., MS, Esch, Robert E., PhD, FAAAAI

“…Pollen grains with uncommon morphologies and disruptions, large numbers of miscellaneous fungal spores, presence of aggregated small (<4mm) spores, unusual…”
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Preservation of epithelial cell barrier function and muted inflammation in resistance to allergic rhinoconjunctivitis from house dust mite challenge by Ahuja, Sunil K., MD, Manoharan, Muthu Saravanan, MS, Harper, Nathan L., MS, Jimenez, Fabio, MS, Hobson, Benjamin D., BS, Martinez, Hernan, MD, Ingale, Puraskar, MS, Liu, Ya-Guang, MD, PhD, Carrillo, Andrew, BS, Lou, Zheng, PhD, Kellog, Dean L., BS, Ahuja, Seema S., MD, Rather, Cynthia G., CCRC, Esch, Robert E., PhD, Ramirez, Daniel A., MD, Clark, Robert A., MD, Nadeau, Kari, MD, PhD, Andrews, Charles P., MD, Jacobs, Robert L., MD, He, Weijing, MD

“…Background An emerging paradigm holds that resistance to the development of allergic diseases, including allergic rhinoconjunctivitis, relates to an intact…”
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Symptom dynamics during repeated serial allergen challenge chamber exposures to house dust mite by Jacobs, Robert L., MD, Andrews, Charles P., MD, Ramirez, Daniel A., MD, Rather, Cynthia G., CCRC, Harper, Nathan, MS, Jimenez, Fabio, BS, Martinez, Hernan, MD, Manoharan, Muthu, MS, Carrillo, Andrew, BS, Gerardi, Margit, RN, PhD, Esch, Robert E., PhD, He, Weijing, MD, Ahuja, Sunil K., MD

“…[...]we suggest that out-of-pollination season challenges with HDM in the ACC might help mitigate the confounding of factors present in the natural setting:…”
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Allergen stabilities and compatibilities in mixtures of high-protease fungal and insect extracts by Grier, Thomas J., PhD, LeFevre, Dawn M., BS, Duncan, Elizabeth A., BS, Esch, Robert E., PhD, Coyne, Terrance C., MD

“…Abstract Background Current practice guidelines state that protease-rich fungal and insect extracts can be combined when preparing immunotherapy vaccines, but…”
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Allergen Compatibilities in Extract Mixtures by Esch, Robert E., PhD, Grier, Thomas J., PhD

“…Stability studies with a few well-characterized allergen extracts have yielded useful information about the shelf-life of these products stored under various…”
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Development and preclinical evaluation of an alphavirus replicon particle vaccine for cytomegalovirus by Reap, Elizabeth A, Morris, John, Dryga, Sergey A, Maughan, Maureen, Talarico, Todd, Esch, Robert E, Negri, Sarah, Burnett, Bruce, Graham, Andrew, Olmsted, Robert A, Chulay, Jeffrey D

“…Abstract We used a replication-incompetent, single-cycle, alphavirus replicon vector system to produce virus-like replicon particles (VRP) expressing the…”
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Sublingual-oral administration of standardized allergenic extracts: phase 1 safety and dosing results by Esch, Robert E., PhD, Bush, Robert K., MD, Peden, David, MD, Lockey, Richard F., MD

“…Background European studies provide a preponderance of evidence for sublingual allergen immunotherapy (SLIT) safety and efficacy, but they use allergen…”
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Relative Potency in SPT of Solution and Tablet SLIT Allergen Extracts of Timothy Grass Pollen from 2 European Manufacturers Compared to a US Reference Extract by Larenas Linnemann, Désirée E.S., MD, FAAAAI, Esch, Robert E., PhD, FAAAAI, Singh, Jaswinder, Matta, Juan Jose, MD, Rosario, Nelson A., MD, PhD, FAAAAI, Maspero, Jorge F., MD, Michels, Alexandra, PhD, Mosges, Ralph, MD, FAAAAI

“…Rationale To compare the relative potency in skin tests of solution and tablet extracts of Timothy grass pollen (TIM) of 2 European manufacturers (ALK-Abelló,…”
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Understanding differences in allergen immunotherapy products and practices in North America and Europe by Mahler, Vera, Esch, Robert E., Kleine-Tebbe, Jörg, Lavery, William J., Plunkett, Greg, Vieths, Stefan, Bernstein, David I.

“…Allergen immunotherapy (AIT) is thought to be clinically effective and safe in treating allergic rhinitis, asthma, and stinging insect allergy in Europe and…”
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Stability of standardized grass, dust mite, cat, and short ragweed allergens after mixing with mold or cockroach extracts by Grier, Thomas J., PhD, LeFevre, Dawn M., BS, Duncan, Elizabeth A., BS, Esch, Robert E., PhD

“…Background Limited data are available on the immunochemical compatibilities of standardized and nonstandardized allergen extracts in immunotherapy vaccines…”
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Stability and mixing compatibility of dog epithelia and dog dander allergens by Grier, Thomas J., PhD, LeFevre, Dawn M., BS, Duncan, Elizabeth A., BS, Esch, Robert E., PhD

“…Background Little information or data are available concerning the stability and compatibility of dog epithelia and dog dander allergens. Objective To…”
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The Clinical Relevance of Pollen Versus Fungal Spores in Allergic Diseases by Codina, Rosa, Esch, Robert E., Lockey, Richard F.

“…Pollen and fungal spores are associated with seasonal and perennial allergies. However, most scientific literature thus far suggests that pollen allergy is…”
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Immunotherapy Preparation Guidelines, Rules, and Regulation by Esch, Robert E., Plunkett, Greg A.

“…Allergen immunotherapy has been used to treat allergic diseases for more than 100 years. In the U.S., the preparation of diagnostic and therapeutic extracts…”
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