Search Results - "Escarcena, Ricardo"
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Diterpenes Synthesized from the Natural Serrulatane Leubethanol and Their in Vitro Activities against Mycobacterium tuberculosis
Published in Molecules (Basel, Switzerland) (21-04-2015)“…Seventeen new derivatives of the natural diterpene leubethanol, including some potential pro-drugs, with changes in the functionality of the aliphatic chain or…”
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Trypanocidal Activity of Long Chain Diamines and Aminoalcohols
Published in Molecules (Basel, Switzerland) (23-06-2015)“…Thirteen aminoalcohols and eight diamines were obtained and tested against Trypanosoma cruzi epimastigotes strains MG, JEM and CL-B5 clone. Some of them were…”
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3
Synthesis, bioevaluation and docking studies of some 2-phenyl-1H-benzimidazole derivatives as anthelminthic agents against the nematode Teladorsagia circumcincta
Published in European journal of medicinal chemistry (15-12-2020)“…Gastrointestinal nematode infections are the main diseases in herds of small ruminants. Resistance to the main established drugs has become a worldwide…”
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4
Anthelmintic activity of aminoalcohol and diamine derivatives against the gastrointestinal nematode Teladorsagia circumcincta
Published in Veterinary parasitology (01-08-2021)“…•18 aminoalcohol and 16 diamine derivatives were tested in vitro against Teladorsagia circumcincta.•Compound 30 (1.01 ± 0.04 μM) displayed the best EC50 value…”
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5
Imidazo[2,1-a]isoindole scaffold as an uncharted structure active on Leishmania donovani
Published in European journal of medicinal chemistry (15-11-2019)“…The human protozoan parasites Leishmania donovani and L. infantum are the causative agents of visceral leishmaniasis, as such, responsible for approximately…”
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Anti-hyperalgesic effects of two sphingosine derivatives in different acute and chronic models of hyperalgesia in mice
Published in Pharmacological reports (01-08-2018)“…The study evaluated the effects of two sphingosine derivatives N-(2-tert-butoxycarbamylhexadecyl)glutaramide (AA) and N-(1-benzyloxyhexadec-2-yl)glutaramide…”
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7
Mechanisms of action of substituted β-amino alkanols on Leishmania donovani
Published in Antimicrobial agents and chemotherapy (01-02-2015)“…Leishmaniasis is the protozoan disease second in importance for human health, superseded only by malaria; however, the options for chemotherapeutic treatment…”
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Efficacious In Vitro and In Vivo Effects of Dihydrosphingosine–Ethambutol Analogues Against Susceptible and Multi-drug-resistant Mycobacterium tuberculosis
Published in Archives of medical research (01-05-2016)“…Background and Aims Tuberculosis (TB) is a major worldwide health problem in part due to the lack of new drugs and the emergence of multidrug-resistant strains…”
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9
In vitro and in vivo evaluation of 2-aminoalkanol and 1,2-alkanediamine derivatives against Strongyloides venezuelensis
Published in Parasites & vectors (28-06-2016)“…Strongyloidiasis is a parasitic disease widely present in tropical and subtropical areas. Strongyloides stercoralis represents the main species that infects…”
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Diamine and aminoalcohol derivatives active against Trypanosoma brucei
Published in Bioorganic & medicinal chemistry letters (01-01-2012)“…New agents inducing lethal alterations in the flagellar pocket structure of Trypanosome brucei are described. Twenty compounds selected as representative…”
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Synthesis of Leubethanol derivatives and evaluation against Mycobacterium tuberculosis
Published in Bioorganic & medicinal chemistry (01-07-2012)“…Twenty-five derivatives of the natural diterpene leubethanol are described and tested against Mycobacterium tuberculosis H37Rv. Twenty-five derivatives of the…”
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12
New antinociceptive agents related to dihydrosphingosine
Published in Pharmacological reports (01-09-2010)“…The main objective of this study was to evaluate the antinociceptive activity of three ethylenediamine derivatives and three β-aminoethanol lipidic derivatives…”
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13
Simple dihydrosphyngosine analogues with potent activity against MDR- Mycobacterium tuberculosis
Published in Bioorganic & medicinal chemistry letters (01-10-2009)“…A number of dihydrosphingosine analogues were tested in vitro against several strains of Mycobacterium tuberculosis ( MTB). Three ( 3, 4b and 8b) out of the…”
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14
Guatemalan plants extracts as virucides against HIV-1 infection
Published in Phytomedicine (Stuttgart) (01-06-2008)“…Prevention methods to avoid transmission of pathogens, including HIV, are crucial in the control of infectious diseases, not only to block epidemic spread but…”
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Synthesis and characterization of fluorinated copolyetherimides with CH2C6F13 side chains based on the ULTEM™ structure
Published in Journal of fluorine chemistry (01-12-2005)Get full text
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Synthesis and characterization of fluorinated copolyetherimides with CH 2 C 6F 13 side chains based on the ULTEM™ structure
Published in Journal of fluorine chemistry (2005)“…The hydrophobicity and the thermal properties of soft non-porous films are studied. ▪ Step polymerization of bisphenol-A diphthalic anhydride (BAPA) with…”
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Synthesis and characterization of fluorinated copolyetherimides with -CH2-C6F13 side chains based on the ULTEM structure
Published in Journal of fluorine chemistry (01-12-2005)“…Step polymn. of bisphenol A diphthalic anhydride (BAPA) with various mixts. from m-phenylene diamine (m-PDA) and 2-(perfluorohexylmethyl)butan-1,4-diamine…”
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Synthesis of aliphatic diamine and polyetherimide with long perfluoroalkyl side chain
Published in Journal of fluorine chemistry (28-09-2002)“…The monomer, 2-(perfluorohexylmethyl)butan-1,4-diamine (TFD), was prepared from itaconic acid dimethyl ester via the addition of perfluorohexyl iodide followed…”
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The use of acyclic monoterpenes in the preparation of β-pyrones: Synthesis of the right-hand fragment of Usneoidone E
Published in Tetrahedron (20-03-1995)“…The right hand fragment, 36, of Usneoidone E, 1, a powerful antiviral and antitumoural agent has been synthesized from the β-pyrone 32. Using linalool as…”
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