Search Results - "Escalante, Leah E."
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Single-cell RNA-seq supports a developmental hierarchy in human oligodendroglioma
Published in Nature (London) (10-11-2016)“…A single sentence summarizing your paper (websum), which will appear online on the table of contents and in e-alerts, has been provided below. Please check…”
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2
Single-cell RNA sequencing reveals intrinsic and extrinsic regulatory heterogeneity in yeast responding to stress
Published in PLoS biology (14-12-2017)“…From bacteria to humans, individual cells within isogenic populations can show significant variation in stress tolerance, but the nature of this heterogeneity…”
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3
The genetic basis of aneuploidy tolerance in wild yeast
Published in eLife (07-01-2020)“…Aneuploidy is highly detrimental during development yet common in cancers and pathogenic fungi - what gives rise to differences in aneuploidy tolerance remains…”
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4
Macrophages and mesenchymal stromal cells support survival and proliferation of multiple myeloma cells
Published in British journal of haematology (01-08-2012)“…Summary Multiple myeloma (MM) is characterized by almost exclusive tropism of malignant cells for the bone marrow (BM) milieu. The survival and proliferation…”
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5
The role of stress-activated RNA-protein granules in surviving adversity
Published in RNA (Cambridge) (01-07-2021)“…Severe environmental stress can trigger a plethora of physiological changes and, in the process, significant cytoplasmic reorganization. Stress-activated…”
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Decoupling genetics, lineages, and microenvironment in IDH-mutant gliomas by single-cell RNA-seq
Published in Science (American Association for the Advancement of Science) (31-03-2017)“…Tumor subclasses differ according to the genotypes and phenotypes of malignant cells as well as the composition of the tumor microenvironment (TME). We…”
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Developmental and oncogenic programs in H3K27M gliomas dissected by single-cell RNA-seq
Published in Science (American Association for the Advancement of Science) (20-04-2018)“…Gliomas with histone H3 lysine27-to-methionine mutations (H3K27M-glioma) arise primarily in the midline of the central nervous system of young children,…”
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Comparison of Breast and Abdominal Adipose Tissue Mesenchymal Stromal/Stem Cells in Support of Proliferation of Breast Cancer Cells
Published in Cancer investigation (01-10-2013)“…In this study, we compared MSCs from breast and abdominal tissue in terms of their expression of genes deemed important in the support of breast cancer growth…”
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Biologic and immunomodulatory properties of mesenchymal stromal cells derived from human pancreatic islets
Published in Cytotherapy (Oxford, England) (01-09-2012)“…Abstract Background aims Mesenchymal stromal cells (MSC) have now been shown to reside in numerous tissues throughout the body, including the pancreas. Ex vivo…”
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10
The genetic basis of aneuploidy tolerance in wild yeast
Published in eLife (07-01-2020)“…Aneuploidy is highly detrimental during development yet common in cancers and pathogenic fungi – what gives rise to differences in aneuploidy tolerance remains…”
Get full text
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11
PTPS-06SINGLE-CELL TRANSCRIPTOME ANALYSIS IN PEDIATRIC HIGH-GRADE GLIOMA
Published in Neuro-oncology (Charlottesville, Va.) (01-11-2015)Get full text
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HG-110SINGLE-CELL TRANSCRIPTOME ANALYSIS IN PEDIATRIC HEMISPHERIC AND MIDLINE HIGH-GRADE GLIOMAS
Published in Neuro-oncology (Charlottesville, Va.) (01-06-2016)Get full text
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