Search Results - "Erzurumlu, Yalcın"

Androgen Mediated Regulation of Endoplasmic Reticulum-Associated Degradation and its Effects on Prostate Cancer by Erzurumlu, Yalcin, Ballar, Petek

“…The endoplasmic reticulum (ER) comprises thirty percent of the newly translated proteins in eukaryotic cells. The quality control mechanism within the ER…”
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Potent carotenoid astaxanthin expands the anti-cancer activity of cisplatin in human prostate cancer cells by Erzurumlu, Yalcin, Catakli, Deniz, Dogan, Hatice Kubra

“…Prostate cancer (PCa) is the second most common type of cancer and the sixth cause of death in men worldwide. Radiotherapy and immunotherapy are commonly used…”
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Agomelatine confers neuroprotection against cisplatin-induced hippocampal neurotoxicity by Cankara, Fatma Nihan, Günaydın, Caner, Çelik, Zülfinaz Betül, Şahin, Yasemin, Pekgöz, Şakir, Erzurumlu, Yalçın, Gülle, Kanat

“…Neurotoxicity caused by cisplatin is a major obstacle during chemotherapy. Oxidative stress and inflammation are considered the primary mechanism behind…”
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Identification of a Noncanonical Necrotic Cell Death Triggered via Enhanced Proteolysis by a Novel Sapogenol Derivative by Üner, Göklem, Tag̀, Özgür, Erzurumlu, Yalçın, Kirmizibayrak, Petek Ballar, Bedir, Erdal

“…Small molecules which activate distinct cell death pathways have promising high potential for anticancer drug research. Especially, regulated necrosis draws…”
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Novel regulation mechanism of adrenal cortisol and DHEA biosynthesis via the endogen ERAD inhibitor small VCP-interacting protein by Ilhan, Recep, Üner, Göklem, Yilmaz, Sinem, Atalay Sahar, Esra, Cayli, Sevil, Erzurumlu, Yalcin, Gozen, Oguz, Ballar Kirmizibayrak, Petek

“…Endoplasmic reticulum-associated degradation (ERAD) is a well-characterized mechanism of protein quality control by removal of misfolded or unfolded proteins…”
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Selenium ameliorates inflammation by decreasing autophagic flux and mitogen‐activated protein kinase signalling on experimentally induced rat periapical lesions by Bolat, Nergiz, Erzurumlu, Yalçin, Aşcı, Halil, Özmen, Özlem, Üreyen Kaya, Bulem

“…Aim To reveal the molecular mechanisms that targets mitogen‐activated protein kinase (MAPK) signalling and the autophagic flux and to investigate the possible…”
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Design and synthesis of aminothiazole-benzazole based amide: antiproliferative, antimigration activity and molecular docking studies by Arslan Karahan, Gülnur, Erzurumlu, Yalçın, Muhammed, Muhammed Tilahun, Özçelik, Azime Berna

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Agomelatine ameliorates doxorubicin-induced cortical and hippocampal brain injury via inhibition of TNF-alpha/NF-kB pathway by Savran, Mehtap, Asci, Sanem, Gulle, Kanat, Aslankoc, Rahime, Asci, Halil, Karakuyu, Nasif Fatih, Erzurumlu, Yalçın, Kaynak, Mine

“…Side effects of doxorubicin (DOX) are mainly due to oxidative stress, with the involvement of inflammatory and apoptotic mechanisms. Agomelatine (AGO) is a…”
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Circadian Oscillation Pattern of Endoplasmic Reticulum Quality Control (ERQC) Components in Human Embryonic Kidney HEK293 Cells by Erzurumlu, Yalcin, Catakli, Deniz, Dogan, Hatice Kubra

“…The circadian clock regulates the "push-pull" of the molecular signaling mechanisms that arrange the rhythmic organization of the physiology to maintain…”
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Anticancer Effect of Theranekron ® on Androgen-Dependent Prostate Cancer Cells by Erzurumlu, Yalçın, Doğan, Hatice Kübra, Çataklı, Deniz

“…Prostate cancer (PCa) is a significant health problem in men worldwide. Although there are numerous treatment choices for PCa, acquired resistance limits…”
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Estrogens drive the endoplasmic reticulum-associated degradation and promote proto-oncogene c-Myc expression in prostate cancer cells by androgen receptor/estrogen receptor signaling by Erzurumlu, Yalcin, Dogan, Hatice Kubra, Catakli, Deniz, Aydogdu, Esra, Muhammed, Muhammed Tilahun

“…The tumorigenic properties of prostate cancer are regulated by advanced hormonal regulation-mediated complex molecular signals. Therefore, characterizing the…”
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Design and Synthesis of New Aminothiazole‐Benzazole Based Ureas: Antiproliferative and Antimigration Activity Studies by Arslan, Gülnur, Erzurumlu, Yalçın, Muhammed, Muhammed Tilahun, Özçelik, Azime Berna

“…In our quest to develop new treatments for cancer, we synthesized and tested a series of urea‐functionalized aminothiazole‐benzazole analogs. Our primary focus…”
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Potential Hepatoprotective Effects of Irbesartan, an Accessible Angiotensin II Receptor Blocker, Against Cisplatin-Induced Liver Injury in a Rat Model by Ertunç, Onur, Erzurumlu, Yalçın, Savran, Mehtap, Çataklı, Deniz, Doğan Kıran, Eltaf, Pekgöz, Şakir

“…Drug-induced liver injury is a common adverse reaction that frequently occurs with chemotherapeutic agents, such as cisplatin (CIS). This study seeks to…”
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Synthesis and evaluation of pyridinium‐hydrazone derivatives as potential antitumoral agents by Parlar, Sülünay, Erzurumlu, Yalçın, Ilhan, Recep, Ballar Kırmızıbayrak, Petek, Alptüzün, Vildan, Erciyas, Ercin

“…The hydrazones of 4‐hydrazinylpyridinium bearing alkylphenyl groups on pyridinium nitrogen were synthesized and evaluated for their cytotoxic activity against…”
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HERPUD1, a Member of the Endoplasmic Reticulum Protein Quality Control Mechanism, may be a Good Target for Suppressing Tumorigenesis in Breast Cancer Cells by Erzurumlu, Yalçın, Doğanlar, Yağmur, Doğan, Hatice Kübra, Çataklı, Deniz

“…Breast cancer is the most frequently diagnosed cancer type and the second leading cause of cancer-related death in women. Recent studies have highlighted the…”
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Ramelteon and mechanism of its restorative effect in an experimental lung disease model by Armağan, İlkay, Aşcı, Halil, Erzurumlu, Yalçın, Özkula, Songül, Hasseyid, Nursel, Kumbul Doğuç, Duygu, Okuyucu, Gözde, Varel, Ahmetcan

“…Methotrexate (MTX) is an anticancer agent widely used in clinical practice for various oncological, rheumatological, autoimmune, and inflammatory diseases…”
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The effects of agomelatine in cisplatin-induced toxicity on the kidney and liver tissues: In vivo study by Cankara, Fatma Nihan, Günaydın, Caner, Çelik, Zülfinaz Betül, Şahin, Yasemin, Pekgöz, Şakir, Erzurumlu, Yalçın, Gülle, Kanat

“…Abstract Nephrotoxicity and hepatotoxicity are frequently seen adverse effects during cisplatin chemotherapy. In this study, we investigated the effects of…”
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Anti-Quorum Sensing Activity of Vitis vinifera L. Seed Extract on Some Bacteria: A Greener Alternative Against Antimicrobial Resistance by Ibrahim, Bashar MS, Dereli, Fatma Tuğçe, Erzurumlu, Yalçın, Önem, Ebru, Arin, Evren, Muhammed, Muhammed T.

“…In the present study, the seed extract of Vitis vinifera  L. (grape) prepared with the methanol-ethanol mixture (volume ratio of 1:1) was evaluated for…”
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Deuterium-Labeled Precursor Feeding Reveals a New pABA-Containing Meroterpenoid from the Mango Pathogen Xanthomonas citri pv. mangiferaeindicae by Saleh, Hesham, Petras, Daniel, Mainz, Andi, Kerwat, Dennis, Nalbantsoy, Ayse, Erzurumlu, Yalcin, Süssmuth, Roderich D

“…A new para-aminobenzoic-acid-containing natural product from the mango pathogenic organism Xanthomonas citri pv. mangiferaeindicae is described. By means of…”
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Gemcitabine hydrochloride microspheres used for intravesical treatment of superficial bladder cancer: a comprehensive in vitro/ex vivo/in vivo evaluation by Karavana, Sinem Yaprak, Şenyiğit, Zeynep Ay, Çalışkan, Çağrı, Sevin, Gülnur, Özdemir, Derya İlem, Erzurumlu, Yalçın, Şen, Sait, Baloğlu, Esra

“…Bladder cancer is responsible for more than 130,000 deaths annually worldwide. Intravesical delivery of chemotherapeutic agents provides effective drug…”
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