Search Results - "Erwin, Michael"
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PIM Kinase Inhibition Attenuates the Malignant Progression of Metastatic Hepatoblastoma
Published in International journal of molecular sciences (28-12-2023)“…Hepatoblastoma is the most common primary pediatric liver tumor. Children with pulmonary metastases at diagnosis experience survival rates as low as 25%. We…”
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PP2A activation overcomes leptomeningeal dissemination in group 3 medulloblastoma
Published in The Journal of biological chemistry (01-11-2024)“…Leptomeningeal dissemination (LMD) is the primary cause of treatment failure in children with group 3 medulloblastoma (MB). Building on our previous work on…”
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The Effects of Protein Phosphatase 2A Activation with Novel Tricyclic Sulfonamides on Hepatoblastoma
Published in Journal of pediatric surgery (01-06-2023)“…The tumor suppressor, protein phosphatase 2A (PP2A), is downregulated in hepatoblastoma. We aimed to examine the effects of two novel compounds of the…”
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Comparisons of Sleep, Demographics, and Health-Related Variables in Older Long and Average Duration Sleepers
Published in Sleep science (São Paulo, SP ) (01-06-2023)“…Introduction Long sleep duration is associated with many health risks, particularly in older adults, but little is known about other characteristics associated…”
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Pre-Clinical Study Evaluating Novel Protein Phosphatase 2A Activators as Therapeutics for Neuroblastoma
Published in Cancers (13-04-2022)“…Protein phosphatase 2A (PP2A) functions as an inhibitor of cancer cell proliferation, and its tumor suppressor function is attenuated in many cancers. Previous…”
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Effects of Local Shoreline and Subestuary Watershed Condition on Waterbird Community Integrity: Influences of Geospatial Scale and Season in the Chesapeake Bay
Published in Estuaries and coasts (01-09-2018)“…In many coastal regions throughout the world, there is increasing pressure to harden shorelines to protect human infrastructures against sea level rise, storm…”
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Preclinical evidence for employing MEK inhibition in NRAS mutated pediatric gastroenteropancreatic neuroendocrine-like tumors
Published in Translational oncology (01-09-2024)“…•Targetable NRAS mutation were identified in pediatric neuroendocrine-like tumors.•Primary and metastatic PDX cells harbor phenotypic and genetic…”
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Novel PP2A-Activating Compounds in Neuroblastoma
Published in Cancers (15-11-2024)“…Background: Neuroblastoma (NB) remains one of the deadliest pediatric solid tumors. Recent advancements aimed at improving outcomes have been insufficient, and…”
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Transforming Veteran Rehabilitation Care: Learnings from a Remote Digital Approach for Musculoskeletal Pain
Published in Healthcare (Basel) (01-08-2024)“…While musculoskeletal pain (MSP) stands as the most prevalent health condition among Veterans, timely and high-quality care is often hindered due to access…”
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Correction to: Effects of Local Shoreline and Subestuary Watershed Condition on Waterbird Community Integrity: Influences of Geospatial Scale and Season in the Chesapeake Bay
Published in Estuaries and coasts (01-05-2019)“…The article Effects of Local Shoreline and Subestuary Watershed Condition on Waterbird Community Integrity: Influences of Geospatial Scale and Season in the…”
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Antibiotic dosing during sustained low-efficiency dialysis: Special considerations in adult critically ill patients
Published in Critical care medicine (01-03-2011)“…OBJECTIVE:To address issues of antibiotic dosing during sustained low-efficiency dialysis by using available pharmacokinetic data, intermittent and continuous…”
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Targeting High-Risk Neuroblastoma Patient-Derived Xenografts with Oncolytic Virotherapy
Published in Cancers (01-02-2022)“…Cancer is the leading cause of death by disease in children, and over 15% of pediatric cancer-related mortalities are due to neuroblastoma. Current treatment…”
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Using 3D-bioprinted models to study pediatric neural crest-derived tumors
Published in International journal of bioprinting (01-01-2023)“…The use of three-dimensional (3D) bioprinting has remained at the forefront of tissue engineering and has recently been employed for generating bioprinted…”
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Standardization and Application of an Index of Community Integrity for Waterbirds in the Chesapeake Bay, USA
Published in Waterbirds (De Leon Springs, Fla.) (01-09-2017)“…In recent decades, there has been increasing interest in the application of ecological indices to assess ecosystem condition in response to anthropogenic…”
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Fathering after Military Deployment: Parenting Challenges and Goals of Fathers of Young Children
Published in Health & social work (01-02-2014)“…Although often eagerly anticipated, reuni cation after deployment poses challenges for families, including adjusting to the parent-soldier's return,…”
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Creating Community for Women Veterans Through Social Networking Organizations: A Secondary Analysis of Team Red, White, and Blue New Member Surveys
Published in Journal of community engagement and scholarship (22-09-2021)“…In an effort to better understand mental health and enrichment differences between veteran women and men in a veteran service organization (VSO), a research…”
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Team Red, White & Blue: a community-based model for harnessing positive social networks to enhance enrichment outcomes in military veterans reintegrating to civilian life
Published in Translational behavioral medicine (17-07-2018)“…Military service assimilates individuals into a socially cohesive force to address dangerous and traumatic situations that have no counterpart in civilian…”
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Regional differences in BMI, obesity, and exercise frequency in a large veteran service organization: A secondary analysis of new veteran member surveys from Team Red, White & Blue
Published in Preventive medicine reports (01-12-2018)“…Abstract The purpose of the present study was to examine regional differences in average self-reported BMI, obesity prevalence, and frequent exercise (FE)…”
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BELIEVE - Stroke Recovery Foundation: Stroke Recovery with Purpose
Published in North Carolina medical journal (Durham, N.C.) (01-09-2023)Get full text
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Mapping avian influenza transmission risk at the interface of domestic poultry and wild birds
Published in Frontiers in public health (2013)“…Emergence of avian influenza viruses with high lethality to humans, such as the currently circulating highly pathogenic A(H5N1) (emerged in 1996) and A(H7N9)…”
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