Search Results - "Erwin, B"
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Microelectrode targeting of the subthalamic nucleus for deep brain stimulation surgery
Published in Movement disorders (15-09-2012)“…Though microelectrode recordings likely increase the risks and costs of DBS, incremental improvement in accuracy may translate into improved outcomes that…”
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2
Challenges for future theories of Parkinson pathophysiology
Published in Neuroscience research (01-04-2022)“…•Basal ganglia dynamics are modeled by push-pull systems to explain hypokinesia or hyperkinesia.•Push-pull systems cannot explain the complex orchestration of…”
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Debugging Adaptive Deep Brain Stimulation for Parkinson's Disease
Published in Movement disorders (01-10-2020)Get full text
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Starting from Scratch—Basal Ganglia Pathophysiology
Published in Movement disorders (01-01-2020)Get full text
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Mechanisms of action of deep brain stimulation (DBS)
Published in Neuroscience and biobehavioral reviews (2008)“…Deep brain stimulation (DBS) is remarkably effective for a range of neurological and psychiatric disorders that have failed pharmacological and cell transplant…”
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Therapeutic mechanisms of high-frequency stimulation in Parkinson’s disease and neural restoration via loop-based reinforcement
Published in Proceedings of the National Academy of Sciences - PNAS (10-02-2015)“…Significance We investigated the therapeutic mechanisms of high-frequency stimulation (HFS) in Parkinson’s disease by developing a computational model of the…”
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Modeling and Theories of Pathophysiology and Physiology of the Basal Ganglia-Thalamic-Cortical System: Critical Analysis
Published in Frontiers in human neuroscience (21-09-2016)“…Theories impact the movement disorders clinic, not only affecting the development of new therapies but determining how current therapies are used. Models are…”
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Effects of deep brain stimulation frequency on bradykinesia of Parkinson's disease
Published in Movement disorders (01-02-2014)“…ABSTRACT Deep brain stimulation (DBS) in Parkinson's disease (PD) is frequency‐dependent. Past studies of the effect of DBS frequency, however, involved…”
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Antinociceptive effects of minor cannabinoids, terpenes and flavonoids in Cannabis
Published in Behavioural pharmacology (01-04-2022)“…Cannabis has been used for centuries for its medicinal properties. Given the dangerous and unpleasant side effects of existing analgesics, the chemical…”
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10
Validation of CT-MRI fusion for intraoperative assessment of stereotactic accuracy in DBS surgery
Published in Movement disorders (01-03-2015)Get full text
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11
Functional connectivity in the basal ganglia network differentiates PD patients from controls
Published in Neurology (03-02-2015)Get full text
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Microelectrode recordings and deep brain stimulation surgery-reasoned discussion?
Published in Movement disorders (01-08-2015)Get full text
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Effects of GPi stimulation on human thalamic neuronal activity
Published in Clinical neurophysiology (01-12-2006)“…Determine the effects of globus pallidus interna (GPi) deep brain stimulation (DBS) on ventral oralis posterior nucleus of the thalamic (Vop) neuronal…”
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Upregulating Human Cathelicidin Antimicrobial Peptide LL-37 Expression May Prevent Severe COVID-19 Inflammatory Responses and Reduce Microthrombosis
Published in Frontiers in immunology (12-05-2022)“…COVID-19 is characterized by hyperactivation by inflammatory cytokines and recruitment of macrophages, neutrophils, and other immune cells, all hallmarks of a…”
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15
Clinical response to varying the stimulus parameters in deep brain stimulation for essential tremor
Published in Movement disorders (01-11-2006)“…Deep brain stimulation (DBS) of the ventral intermediate nucleus of the thalamus for essential tremor is sometimes limited by side effects. The mechanisms by…”
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Letter to the editor: Deep brain stimulation without microelectrode recording
Published in Journal of neurosurgery (01-06-2014)Get full text
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Predictors of Parkinson's disease-not quite sound
Published in Movement disorders (01-04-2013)Get full text
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18
Biomonitoring and Digital Data Technology as an Opportunity for Enhancing Animal Study Translation
Published in ILAR journal (31-12-2021)“…The failure of animal studies to translate to effective clinical therapeutics has driven efforts to identify underlying cause and develop solutions that…”
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Microelectrode recordings in DBS-still in need of reasoned discussion
Published in Movement disorders (01-02-2013)Get full text
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Oxytocin receptor knockout mice display deficits in the expression of autism-related behaviors
Published in Hormones and behavior (01-03-2012)“…A wealth of studies has implicated oxytocin (Oxt) and its receptors (Oxtr) in the mediation of social behaviors and social memory in rodents. It has been…”
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