Search Results - "Erwin, A."
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1
Protein adsorption in three dimensions
Published in Biomaterials (01-02-2012)“…Abstract Recent experimental and theoretical work clarifying the physical chemistry of blood-protein adsorption from aqueous-buffer solution to various kinds…”
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2
Neurovascular unit dysfunction as a mechanism of seizures and epilepsy during aging
Published in Epilepsia (Copenhagen) (01-06-2022)“…The term neurovascular unit (NVU) describes the structural and functional liaison between specialized brain endothelium, glial and mural cells, and neurons…”
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3
Long-lasting blood-brain barrier dysfunction and neuroinflammation after traumatic brain injury
Published in Neurobiology of disease (01-11-2020)“…Traumatic brain injury (TBI) causes 10–20% of acquired epilepsy, which typically develops within 2 years post-injury with poorly understood mechanisms. We…”
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4
Birdsong and anthropogenic noise: implications and applications for conservation
Published in Molecular ecology (01-01-2008)“…The dramatic increase in human activities all over the world has caused, on an evolutionary time scale, a sudden rise in especially low-pitched noise levels…”
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Status epilepticus, blood–brain barrier disruption, inflammation, and epileptogenesis
Published in Epilepsy & behavior (01-08-2015)“…Abstract Over the last 15 years, attention has been focused on dysfunction of the cerebral vasculature and inflammation as important players in epileptogenic…”
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Standardization procedure for plasma biomarker analysis in rat models of epileptogenesis: Focus on circulating microRNAs
Published in Epilepsia (Copenhagen) (01-12-2017)“…Summary The World Health Organization estimates that globally 2.4 million people are diagnosed with epilepsy each year. In nearly 30% of these cases, epilepsy…”
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Astrocytes as Guardians of Neuronal Excitability: Mechanisms Underlying Epileptogenesis
Published in Frontiers in neurology (26-11-2020)“…Astrocytes are key homeostatic regulators in the central nervous system and play important roles in physiology. After brain damage caused by e.g., status…”
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Hydroxyl radical scavenging of the compatible solute ectoine generates two N-acetimides
Published in Archives of biochemistry and biophysics (15-10-2019)“…Living cells employ various defence mechanisms against reactive oxygen species and free radicals. Besides protecting enzymes such as superoxide dismutase,…”
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9
Contact activation of blood-plasma coagulation
Published in Biomaterials (01-04-2009)“…Abstract This opinion identifies inconsistencies in the generally-accepted surface biophysics involved in contact activation of blood-plasma coagulation,…”
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10
A novel GABAergic dysfunction in human Dravet syndrome
Published in Epilepsia (Copenhagen) (01-11-2018)“…Summary Objective Dravet syndrome is a rare neurodevelopmental disease, characterized by general cognitive impairment and severe refractory seizures. The…”
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11
The role of vitamin D in human fracture healing: a systematic review of the literature
Published in Bone (New York, N.Y.) (01-07-2014)“…Abstract Introduction Vitamin D is essential for bone mineralization and for the subsequent maintenance of bone quality. Mineralization is part of hard callus…”
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12
GABAA currents are decreased by IL-1β in epileptogenic tissue of patients with temporal lobe epilepsy: implications for ictogenesis
Published in Neurobiology of disease (01-10-2015)“…Abstract Temporal lobe epilepsy (TLE) is the most prevalent form of adult focal onset epilepsy often associated with drug-resistant seizures. Numerous studies…”
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13
Drought Responses of Leaf Tissues from Wheat Cultivars of Differing Drought Tolerance at the Metabolite Level
Published in Molecular plant (01-03-2012)“…Drought has serious effects on the physiology of cereal crops. At the cellular and specifically the metabolite level, many individual compounds are increased…”
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14
Polycomb Proteins Targeted by a Short Repeat RNA to the Mouse X Chromosome
Published in Science (American Association for the Advancement of Science) (31-10-2008)“…To equalize X-chromosome dosages between the sexes, the female mammal inactivates one of her two X chromosomes. X-chromosome inactivation (XCI) is initiated by…”
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15
microRNA‐132 is overexpressed in glia in temporal lobe epilepsy and reduces the expression of pro‐epileptogenic factors in human cultured astrocytes
Published in Glia (01-01-2020)“…Temporal lobe epilepsy (TLE) is a chronic neurological disease in humans, which is refractory to pharmacological treatment in about 30% of the patients…”
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Blood–brain barrier leakage after status epilepticus in rapamycin‐treated rats I: Magnetic resonance imaging
Published in Epilepsia (Copenhagen) (01-01-2016)“…Summary Objective The mammalian target of rapamycin (mTOR) pathway has received increasing attention as a potential antiepileptogenic target. Treatment with…”
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17
WONOEP appraisal: Imaging biomarkers in epilepsy
Published in Epilepsia (Copenhagen) (01-03-2017)“…Summary Neuroimaging offers a wide range of opportunities to obtain information about neuronal activity, brain inflammation, blood–brain barrier alterations,…”
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18
Reduced platelet adhesion and improved corrosion resistance of superhydrophobic TiO2-nanotube-coated 316L stainless steel
Published in Colloids and surfaces, B, Biointerfaces (01-01-2015)“…•We fabricate TiO2 nanotubes (TNTs) with extreme wettabilities on stainless steel.•Crystal phase and wettability affect corrosion resistance and…”
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Targeting oxidative stress improves disease outcomes in a rat model of acquired epilepsy
Published in Brain (London, England : 1878) (01-07-2019)“…Epilepsy therapy is based on antiseizure drugs that treat the symptom, seizures, rather than the disease and are ineffective in up to 30% of patients. There…”
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Blood–brain barrier leakage after status epilepticus in rapamycin‐treated rats II: Potential mechanisms
Published in Epilepsia (Copenhagen) (01-01-2016)“…Summary Objective Blood–brain barrier (BBB) leakage may play a pro‐epileptogenic role after status epilepticus. In the accompanying contrast‐enhanced magnetic…”
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