Search Results - "Errarte, Peio"

The role of cancer-associated fibroblasts in renal cell carcinoma. An example of tumor modulation through tumor/non-tumor cell interactions by Errarte, Peio, Larrinaga, Gorka, López, José I.

“…Therapeutic strategies targeting tumor cell/stroma interactions in Renal Cell Carcinoma. CAF could be activated due to the accumulation HIF-1α in tumor…”
Get full text

The coexpression of fibroblast activation protein (FAP) and basal-type markers (CK 5/6 and CD44) predicts prognosis in high-grade invasive urothelial carcinoma of the bladder by Calvete, Julio, Larrinaga, Gorka, Errarte, Peio, Martín, Ana M., Dotor, Ana, Esquinas, Cristina, Nunes-Xavier, Caroline E., Pulido, Rafael, López, José I., Angulo, Javier C.

“…High-grade urothelial carcinoma (UC) of the bladder is a heterogeneous disease with dismal prognosis. Bladder tumors with basal phenotype are intrinsically…”
Get full text

The expression pattern of pyruvate dehydrogenase kinases predicts prognosis and correlates with immune exhaustion in clear cell renal cell carcinoma by Nunes-Xavier, Caroline E., Emaldi, Maite, Mingo, Janire, Øyjord, Tove, Mælandsmo, Gunhild M., Fodstad, Øystein, Errarte, Peio, Larrinaga, Gorka, Llarena, Roberto, López, José I., Pulido, Rafael

“…Renal cancer cells constitute a paradigm of tumor cells with a glycolytic reprogramming which drives metabolic alterations favouring cell survival and…”
Get full text

Expression and activity of angiotensin-regulating enzymes is associated with prognostic outcome in clear cell renal cell carcinoma patients by Errarte, Peio, Beitia, Maider, Perez, Itxaro, Manterola, Lorea, Lawrie, Charles H, Solano-Iturri, Jon Danel, Calvete-Candenas, Julio, Unda, Miguel, López, José I, Larrinaga, Gorka

“…The discovery of the intrarenal renin-angiotensin system (iRAS), which regulates angiogenesis, cell differentiation and proliferation, has opened new…”
Get full text

Author Correction: The expression pattern of pyruvate dehydrogenase kinases predicts prognosis and correlates with immune exhaustion in clear cell renal cell carcinoma by Nunes‑Xavier, Caroline E., Emaldi, Maite, Mingo, Janire, Øyjord, Tove, Mælandsmo, Gunhild M., Fodstad, Øystein, Errarte, Peio, Larrinaga, Gorka, Llarena, Roberto, López, José I., Pulido, Rafael

Get full text

The Expression of Fibroblast Activation Protein in Clear Cell Renal Cell Carcinomas Is Associated with Synchronous Lymph Node Metastases by Errarte, Peio, Guarch, Rosa, Pulido, Rafael, Blanco, Lorena, Nunes-Xavier, Caroline E, Beitia, Maider, Gil, Javier, Angulo, Javier C, López, José I, Larrinaga, Gorka

“…Clear cell renal cell carcinoma (CCRCC) is a heterogeneous and complex disease that frequently develops distant metastases. Fibroblast activation protein (FAP)…”
Get full text

Impact of B7-H3 expression on metastasis, immune exhaustion and JAK/STAT and PI3K/AKT pathways in clear cell renal cell carcinoma by Emaldi, Maite, Rey-Iborra, Esther, Marín, Ángela, Mosteiro, Lorena, Lecumberri, David, Øyjord, Tove, Roncier, Noémie, Mælandsmo, Gunhild M., Angulo, Javier C., Errarte, Peio, Larrinaga, Gorka, Pulido, Rafael, López, José I., Nunes-Xavier, Caroline E.

“…Immune checkpoint inhibitors in combination with tyrosine kinase inhibitors (TKIs) are improving the response rates of advanced renal cancer patients. However,…”
Get full text

Dipeptidyl-peptidase IV activity is correlated with colorectal cancer prognosis by Larrinaga, Gorka, Perez, Itxaro, Sanz, Begoña, Beitia, Maider, Errarte, Peio, Fernández, Ainhoa, Blanco, Lorena, Etxezarraga, María C, Gil, Javier, López, José I

“…Dipeptidyl-peptidase IV (EC 3.4.14.5) (DPPIV) is a serine peptidase involved in cell differentiation, adhesion, immune modulation and apoptosis, functions that…”
Get full text

Altered expression of fibroblast activation protein-α (FAP) in colorectal adenoma-carcinoma sequence and in lymph node and liver metastases by Solano-Iturri, Jon Danel, Beitia, Maider, Errarte, Peio, Calvete-Candenas, Julio, Etxezarraga, María C, Loizate, Alberto, Echevarria, Enrique, Badiola, Iker, Larrinaga, Gorka

“…Colorectal cancer (CRC) is a major health problem in elderly people because of its high incidence and high mortality rate. Despite early screening programs,…”
Get full text

Soluble PD-L1 Is an Independent Prognostic Factor in Clear Cell Renal Cell Carcinoma by Larrinaga, Gorka, Solano-Iturri, Jon Danel, Errarte, Peio, Unda, Miguel, Loizaga-Iriarte, Ana, Pérez-Fernández, Amparo, Echevarría, Enrique, Asumendi, Aintzane, Manini, Claudia, Angulo, Javier C, López, José I

“…(1). : Immunohistochemical (IHC) evaluation of programmed death-1 (PD-1) and its ligand (PD-L1) is being used to evaluate advanced malignancies with potential…”
Get full text

Altered Tissue and Plasma Levels of Fibroblast Activation Protein-α (FAP) in Renal Tumours by Solano-Iturri, Jon Danel, Errarte, Peio, Etxezarraga, María C., Echevarria, Enrique, Angulo, Javier, López, José I., Larrinaga, Gorka

“…(1) Background: Renal cell carcinoma (RCC) is a heterogeneous and complex disease with only partial response to therapy, high incidence of metastasis and…”
Get full text

Fibroblast activation protein predicts prognosis in clear cell renal cell carcinoma by López, José I., MD, PhD, Errarte, Peio, Erramuzpe, Asier, Guarch, Rosa, MD, PhD, Cortés, Jesús M., PhD, Angulo, Javier C., MD, PhD, Pulido, Rafael, PhD, Irazusta, Jon, PhD, Llarena, Roberto, MD, Larrinaga, Gorka, MD, PhD

“…Summary Clear cell renal cell carcinoma is a complex disease with only partial response to therapy and scarce reliable clinical parameters indicative of…”
Get full text

Integrated mRNA and miRNA Transcriptomic Analyses Reveals Divergent Mechanisms of Sunitinib Resistance in Clear Cell Renal Cell Carcinoma (ccRCC) by Armesto, María, Marquez, Maitane, Arestin, María, Errarte, Peio, Rubio, Ane, Manterola, Lorea, López, Jose I., Lawrie, Charles H.

“…The anti-angiogenic therapy sunitinib remains the standard first-line treatment for meta static clear cell renal cell carcinoma (ccRCC). However, acquired…”
Get full text

Altered Tissue and Plasma Levels of Fibroblast Activation Protein-[alpha] in Renal Tumours by Solano-Iturri, Jon Danel, Errarte, Peio, Etxezarraga, Maria C, Echevarria, Enrique, Angulo, Javier, Lopez, Jose I, Larrinaga, Gorka

“…Malignant epithelial tumour's behaviour in the kidney has traditionally been analysed attending to different prognostic parameters focussed on the…”
Get full text

Erbb4 Is Required for Cerebellar Developmentand Malignant Phenotype of Medulloblastoma by Aldaregia, Juncal, Errarte, Peio, Olazagoitia-Garmendia, Ane, Gimeno, Marian, Uriz, Jose Javier, Gershon, Timothy R, Garcia, Idoia, Matheu, Ander

“…Medulloblastoma is the most common and malignant pediatric brain tumor in childhood. It originates from dysregulation of cerebellar development, due to an…”
Get full text

Erbb4 Is Required for Cerebellar Development and Malignant Phenotype of Medulloblastoma by Aldaregia, Juncal, Errarte, Peio, Olazagoitia-Garmendia, Ane, Gimeno, Marian, Uriz, Jose Javier, Gershon, Timothy R., Garcia, Idoia, Matheu, Ander

“…Medulloblastoma is the most common and malignant pediatric brain tumor in childhood. It originates from dysregulation of cerebellar development, due to an…”
Get full text

(Pro)renin Receptor Expression Increases throughout the Colorectal Adenoma-Adenocarcinoma Sequence and It Is Associated with Worse Colorectal Cancer Prognosis by Beitia, Maider, Solano-Iturri, Jon Danel, Errarte, Peio, Calvete-Candenas, Julio, Loizate, Alberto, Etxezarraga, Mari Carmen, Sanz, Begoña, Larrinaga, Gorka

“…(Pro)renin receptor (PRR) is a protein that takes part in several signaling pathways such as Renin Angiotensin System and Wnt signalling. Its biological role…”
Get full text

Aminopeptidase N Activity Predicts 5-Year Survival in Colorectal Cancer Patients by Sanz, Begoña, Perez, Itxaro, Beitia, Maider, Errarte, Peio, Fernández, Ainhoa, Blanco, Lorena, Estalella, Itziar, Loizate, Alberto, Irazusta, Jon, López, José I., Larrinaga, Gorka

“…BackgroundAminopeptidase N (APN; EC 3.4.11.2) is a membrane dimeric metallopeptidase involved in differentiation, development, and proliferative processes of…”
Get full text

Clinical impact of aspartyl aminopeptidase expression and activity in colorectal cancer by Larrinaga, Gorka, Perez, Itxaro, Ariz, Usue, Sanz, Begoña, Beitia, Maider, Errarte, Peio, Etxezarraga, Carmen, Candenas, M. Luz, Pinto, Francisco M, López, José I

“…Aspartyl aminopeptidase (ASP; EC 3.4.11.21) is a widely distributed and abundant cytosolic enzyme that regulates bioactive peptides such as angiotensin II. It…”
Get full text

Altered Peptidase Activities in Thyroid Neoplasia and Hyperplasia by Andrés, Leire, López, José I., Santaolalla, Francisco, Irazusta, Amaia, Perez, Itxaro, Sanz, Begoña, Beitia, Maider, Errarte, Peio, Blanco, Lorena, Larrinaga, Gorka, Sánchez, Clara E.

“…Papillary thyroid carcinoma (PTC), follicular thyroid adenoma (FTA), and thyroid nodular hyperplasia (TNH) are the most frequent diseases of the thyroid gland…”
Get full text