Search Results - "Ernst Wm. Spannhake"

Transcriptional regulation of lysophosphatidic acid-induced interleukin-8 expression and secretion by p38 MAPK and JNK in human bronchial epithelial cells by Saatian, Bahman, Zhao, Yutong, He, Donghong, Georas, Steve N, Watkins, Tonya, Spannhake, Ernst Wm, Natarajan, Viswanathan

“…HBEpCs (human bronchial epithelial cells) contribute to airway inflammation by secreting a variety of cytokines and chemokines in response to allergens,…”
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Lysophosphatidic Acid Enhances Pulmonary Epithelial Barrier Integrity and Protects Endotoxin-induced Epithelial Barrier Disruption and Lung Injury by He, Donghong, Su, Yanlin, Usatyuk, Peter V., Spannhake, Ernst Wm, Kogut, Paul, Solway, Julian, Natarajan, Viswanathan, Zhao, Yutong

“…Lysophosphatidic acid (LPA), a bioactive phospholipid, induces a wide range of cellular effects, including gene expression, cytoskeletal rearrangement, and…”
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Role of acylglycerol kinase in LPA-induced IL-8 secretion and transactivation of epidermal growth factor-receptor in human bronchial epithelial cells by Kalari, Satish, Zhao, Yutong, Spannhake, Ernst Wm, Berdyshev, Evgeny V, Natarajan, Viswanathan

“…LPA (lysophosphatidic acid) is a potent bioactive phospholipid, which regulates a number of diverse cellular responses through G protein-coupled LPA receptors…”
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Lysophosphatidic Acid Induces Interleukin-13 (IL-13) Receptor α2 Expression and Inhibits IL-13 Signaling in Primary Human Bronchial Epithelial Cells by Zhao, Yutong, He, Donghong, Zhao, Jing, Wang, Lixin, Leff, Alan R., Spannhake, Ernst Wm, Georas, Steve, Natarajan, Viswanathan

“…Interleukin-13 (IL-13), a Th2 cytokine, plays a pivotal role in pathogenesis of bronchial asthma via IL-13 receptor α1 (IL-13Rα1) and IL-4 receptor α (IL-4Rα)…”
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Signal transduction of phorbol 12-myristate 13-acetate (PMA)-induced growth inhibition of human monocytic leukemia THP-1 cells is reactive oxygen dependent by Traore, Kassim, Trush, Michael A., George, Matthew, Spannhake, Ernst Wm, Anderson, Winston, Asseffa, Amha

“…Human monocytic THP-1 cells can be induced to differentiate to macrophages when treated with phorbol 12-myristate 13-acetate (PMA). It is understood that…”
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Lipid phosphate phosphatase-1 regulates lysophosphatidic acid-induced calcium release, NF-κB activation and interleukin-8 secretion in human bronchial epithelial cells by ZHAO, Yutong, USATYUK, Peter V., CUMMINGS, Rhett, SAATIAN, Bahman, HE, Donghong, WATKINS, Tonya, MORRIS, Andrew, SPANNHAKE, Ernst Wm, BRINDLEY, David N., NATARAJAN, Viswanathan

“…LPA (lysophosphatidic acid), a potent bioactive phospholipid, elicits diverse cellular responses through activation of the G-protein-coupled receptors…”
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Regulation of Lysophosphatidic Acid-induced Epidermal Growth Factor Receptor Transactivation and Interleukin-8 Secretion in Human Bronchial Epithelial Cells by Protein Kinase Cδ, Lyn Kinase, and Matrix Metalloproteinases by Zhao, Yutong, He, Donghong, Saatian, Bahman, Watkins, Tonya, Spannhake, Ernst Wm, Pyne, Nigel J., Natarajan, Viswanathan

“…We have demonstrated earlier that lysophosphatidic acid (LPA)-induced interleukin-8 (IL-8) secretion is regulated by protein kinase Cδ (PKCδ)-dependent NF-κB…”
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Lysophosphatidic acid increases soluble ST2 expression in mouse lung and human bronchial epithelial cells by Zhao, Jing, Chen, Qingyuan, Li, Hong, Myerburg, Michael, Spannhake, Ernst Wm, Natarajan, Viswanathan, Zhao, Yutong

“…Lysophosphatidic acid (LPA), a naturally occurring bioactive lysophospholipid increases the expression of both pro-inflammatory and anti-inflammatory mediators…”
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Regulation of COX-2 Expression and IL-6 Release by Particulate Matter in Airway Epithelial Cells by Zhao, Yutong, Usatyuk, Peter V, Gorshkova, Irina A, He, Donghong, Wang, Ting, Moreno-Vinasco, Liliana, Geyh, Alison S, Breysse, Patrick N, Samet, Jonathan M, Spannhake, Ernst Wm, Garcia, Joe G. N, Natarajan, Viswanathan

“…Particulate matter (PM) in ambient air is a risk factor for human respiratory and cardiovascular diseases. The delivery of PM to airway epithelial cells has…”
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Lysophosphatidic Acid Induces Interleukin-13 (IL-13) Receptor alpha 2 Expression and Inhibits IL-13 Signaling in Primary Human Bronchial Epithelial Cells by Zhao, Yutong, He, Donghong, Zhao, Jing, Wang, Lixin, Leff, Alan R, Spannhake, Ernst Wm, Georas, Steve, Natarajan, Viswanathan

“…Interleukin-13 (IL-13), a Th2 cytokine, plays a pivotal role in pathogenesis of bronchial asthma via IL-13 receptor alpha 1 (IL-13R alpha 1) and IL-4 receptor…”
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Lysophosphatidic acid modulates c-Met redistribution and hepatocyte growth factor/c-Met signaling in human bronchial epithelial cells through PKC δ and E-cadherin by Zhao, Yutong, He, Donghong, Stern, Randi, Usatyuk, Peter V., Spannhake, Ernst Wm, Salgia, Ravi, Natarajan, Viswanathan

“…Previously we demonstrated that ligation of lysophosphatidic acid (LPA) to G protein-coupled LPA receptors induces transactivation of receptor tyrosine kinases…”
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Regulation of Lysophosphatidic Acid-induced Epidermal Growth Factor Receptor Transactivation and Interleukin-8 Secretion in Human Bronchial Epithelial Cells by Protein Kinase Cδ, Lyn Kinase, and Matrix Metalloproteinases by Yutong Zhao, Donghong He, Bahman Saatian, Tonya Watkins, Ernst Wm. Spannhake, Nigel J. Pyne, Viswanathan Natarajan

“…We have demonstrated earlier that lysophosphatidic acid (LPA)-induced interleukin-8 (IL-8) secretion is regulated by protein kinase Cδ (PKCδ)-dependent…”
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Regulation of lysophosphatidic acid-induced epidermal growth factor receptor transactivation and interleukin-8 secretion in human bronchial epithelial cells by protein kinase Cdelta, Lyn kinase, and matrix metalloproteinases by Zhao, Yutong, He, Donghong, Saatian, Bahman, Watkins, Tonya, Spannhake, Ernst Wm, Pyne, Nigel J, Natarajan, Viswanathan

“…We have demonstrated earlier that lysophosphatidic acid (LPA)-induced interleukin-8 (IL-8) secretion is regulated by protein kinase Cdelta (PKCdelta)-dependent…”
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Regulation of Lysophosphatidic Acid-induced Epidermal Growth Factor Receptor Transactivation and Interleukin-8 Secretion in Human Bronchial Epithelial Cells by Protein Kinase Cd, Lyn Kinase, and Matrix Metalloproteinases by Zhao, Yutong, He, Donghong, Saatian, Bahman, Watkins, Tonya, Spannhake, Ernst Wm, Pyne, Nigel J, Natarajan, Viswanathan

“…We have demonstrated earlier that lysophosphatidic acid (LPA)-induced interleukin-8 (IL-8) secretion is regulated by protein kinase Cd (PKCd)-dependent NF-B…”
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Lysophosphatidic Acid Induces Interleukin-13 (IL-13) Receptor α2 Expression and Inhibits IL-13 Signaling in Primary Human Bronchial Epithelial Cells by Yutong Zhao, Donghong He, Jing Zhao, Lixin Wang, Alan R. Leff, Ernst Wm. Spannhake, Steve Georas, Viswanathan Natarajan

“…Interleukin-13 (IL-13), a Th2 cytokine, plays a pivotal role in pathogenesis of bronchial asthma via IL-13 receptor α1 (IL-13Rα1) and IL-4 receptor α…”
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Lysophosphatidic acid induces interleukin-13 (IL-13) receptor alpha2 expression and inhibits IL-13 signaling in primary human bronchial epithelial cells by Zhao, Yutong, He, Donghong, Zhao, Jing, Wang, Lixin, Leff, Alan R, Spannhake, Ernst Wm, Georas, Steve, Natarajan, Viswanathan

“…Interleukin-13 (IL-13), a Th2 cytokine, plays a pivotal role in pathogenesis of bronchial asthma via IL-13 receptor alpha1 (IL-13Ralpha1) and IL-4 receptor…”
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Expression of genes for B7-H3 and other T cell ligands by nasal epithelial cells during differentiation and activation by Saatian, Bahman, Yu, Xiao-Ying, Yu, XiaoYing, Lane, Andrew P, Doyle, Thanh, Casolaro, Vincenzo, Spannhake, Ernst Wm

“…Epithelial cells of the human respiratory tract express human leukocyte antigen (HLA) and the costimulatory molecules B7-1 and B7-2. Little is known, however,…”
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Lysophosphatidic acid-induced transactivation of epidermal growth factor receptor regulates cyclo-oxygenase-2 expression and prostaglandin E(2) release via C/EBPbeta in human bronchial epithelial cells by He, Donghong, Natarajan, Viswanathan, Stern, Randi, Gorshkova, Irina A, Solway, Julian, Spannhake, Ernst Wm, Zhao, Yutong

“…We have demonstrated that LPA (lysophosphatidic acid)-induced IL (interleukin)-8 secretion was partly mediated via transactivation of EGFR [EGF (epidermal…”
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Acute topical steroid administration blocks mast cell increase and the late asthmatic response of the canine peripheral airways by Turner, C R, Spannhake, E W

“…Previous studies indicated that mast cell number increased after airway exposure to Ascaris suum antigen (Ag). The following two series of experiments were…”
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The Effects of Ozone on Immune Function by Jakab, George J., Spannhake, Ernst Wm, Canning, Brendan J., Kleeberger, Steven R., Gilmour, Matthew I.

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