Search Results - "Ernst, Madeleine"
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Heavy metal exposure causes changes in the metabolic health-associated gut microbiome and metabolites
Published in Environment international (01-05-2019)“…Exposure to arsenic and cadmium is common. Epidemiological and animal studies have suggested that exposure to these two heavy metals can cause metabolic health…”
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Mass spectrometry in plant metabolomics strategies: from analytical platforms to data acquisition and processing
Published in Natural product reports (01-01-2014)“…Covering: up to 2013. Plant metabolomics is a relatively recent research field that has gained increasing interest in the past few years. Up to the present day…”
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MolNetEnhancer: Enhanced Molecular Networks by Integrating Metabolome Mining and Annotation Tools
Published in Metabolites (16-07-2019)“…Metabolomics has started to embrace computational approaches for chemical interpretation of large data sets. Yet, metabolite annotation remains a key…”
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Identification of the Bacterial Biosynthetic Gene Clusters of the Oral Microbiome Illuminates the Unexplored Social Language of Bacteria during Health and Disease
Published in mBio (16-04-2019)“…Small molecules are the primary communication media of the microbial world. Recent bioinformatic studies, exploring the biosynthetic gene clusters (BGCs) which…”
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Deciphering complex metabolite mixtures by unsupervised and supervised substructure discovery and semi-automated annotation from MS/MS spectra
Published in Faraday discussions (15-08-2019)“…Complex metabolite mixtures are challenging to unravel. Mass spectrometry (MS) is a widely used and sensitive technique for obtaining structural information of…”
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Comprehensive mass spectrometry‐guided phenotyping of plant specialized metabolites reveals metabolic diversity in the cosmopolitan plant family Rhamnaceae
Published in The Plant journal : for cell and molecular biology (01-06-2019)“…Summary Plants produce a myriad of specialized metabolites to overcome their sessile habit and combat biotic as well as abiotic stresses. Evolution has shaped…”
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A multi-omics approach unravels metagenomic and metabolic alterations of a probiotic and synbiotic additive in rainbow trout (Oncorhynchus mykiss)
Published in Microbiome (30-01-2022)“…Animal protein production is increasingly looking towards microbiome-associated services such as the design of new and better probiotic solutions to further…”
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Untargeted mass spectrometry-based metabolomics approach unveils molecular changes in raw and processed foods and beverages
Published in Food chemistry (01-01-2020)“…•First large-scale food composition analysis using mass spectral molecular networking.•A methodological pipeline for compound discovery applicable to diverse…”
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A UHPLC-HRMS based metabolomics and chemoinformatics approach to chemically distinguish ‘super foods’ from a variety of plant-based foods
Published in Food chemistry (30-05-2020)“…•Study of molecular composition of superfood analyzing the metabolomic pattern.•Untargeted mass spectrometry and molecular network to obtain an overview of all…”
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10
Multi-omics to predict changes during cold pressor test
Published in BMC genomics (19-11-2022)“…Abstract Background The cold pressor test (CPT) is a widely used pain provocation test to investigate both pain tolerance and cardiovascular responses. We…”
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11
Unraveling the metabolomic architecture of autism in a large Danish population-based cohort
Published in BMC medicine (19-07-2024)“…The prevalence of autism in Denmark has been increasing, reaching 1.65% among 10-year-old children, and similar trends are seen elsewhere. Although there are…”
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Multi-omic analyses of triptan-treated migraine attacks gives insight into molecular mechanisms
Published in Scientific reports (31-07-2023)“…Migraine is a common, polygenic disorder that is characterized by moderate to severe headache attacks. Migraine attacks are commonly treated with triptans,…”
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Home chemical and microbial transitions across urbanization
Published in Nature microbiology (01-01-2020)“…Urbanization represents a profound shift in human behaviour, and has considerable cultural and health-associated consequences 1 , 2 . Here, we investigate…”
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Mass Spectrometry of Flavonoid Vicenin-2, Based Sunlight Barriers in Lychnophora species
Published in Scientific reports (07-03-2014)“…Lychnophora salicifolia plants collected from four different places in Brazil (three states: Goias, Minas Gerais and Bahia) revealed a conserved accumulation…”
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Metabolic signature of the pathogenic 22q11.2 deletion identifies carriers and provides insight into systemic dysregulation
Published in Translational psychiatry (14-12-2023)“…Large deletions at chromosome 22q11.2 are known to cause severe clinical conditions collectively known as 22q11.2 deletion syndrome. Notwithstanding the…”
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Assessing Specialized Metabolite Diversity in the Cosmopolitan Plant Genus Euphorbia L
Published in Frontiers in plant science (02-07-2019)“…Coevolutionary theory suggests that an arms race between plants and herbivores yields increased plant specialized metabolite diversity and the geographic…”
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Identification of compounds responsible for the anthelmintic effects of chicory (Cichorium intybus) by molecular networking and bio-guided fractionation
Published in International journal for parasitology -- drugs and drug resistance (01-04-2021)“…Increasing resistance towards anthelmintic drugs has necessitated the search for alternative treatments for the control of gastrointestinal nematode parasites…”
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Vertical Transfer of Metabolites Detectable from Newborn's Dried Blood Spot Samples Using UPLC-MS: A Chemometric Study
Published in Metabolites (20-01-2022)“…The pregnancy period and first days of a newborn's life is an important time window to ensure a healthy development of the baby. This is also the time when the…”
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Biomonitoring of Polycyclic Aromatic Hydrocarbon Deposition in Greenland Using Historical Moss Herbarium Specimens Shows a Decrease in Pollution During the 20th Century
Published in Frontiers in plant science (15-07-2020)“…Although most point sources of persistent organic pollutants (POPs), including polycyclic aromatic hydrocarbons (PAHs), are at lower latitudes, the Arctic…”
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Metabolic Profiling of Interspecies Interactions During Sessile Bacterial Cultivation Reveals Growth and Sporulation Induction in Paenibacillus amylolyticus in Response to Xanthomonas retroflexus
Published in Frontiers in cellular and infection microbiology (29-03-2022)“…The toolbox available for microbiologists to study interspecies interactions is rapidly growing, and with continuously more advanced instruments, we are able…”
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