Search Results - "Ernst, Darwin"

Secondary structure analysis of the scrapie-associated protein PrP 27-30 in water by infrared spectroscopy by Caughey, Byron W, Dong, Aichun, Bhat, Kolari S, Ernst, Darwin, Hayes, Stanley F, Caughey, Winslow S

“…A protease-resistant form of the protein PrP (PrP-res) accumulates in tissues of mammals infected with scrapie, Creutzfeldt-Jakob disease, and related…”
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Neuron-specific expression of a hamster prion protein minigene in transgenic mice induces susceptibility to hamster scrapie agent by Race, Richard E., Priola, Suzette A., Bessen, Richard A., Ernst, Darwin, Dockter, Janel, Rall, Glenn F., Mucke, Lennart, Chesebro, Bruce, Oldstone, Michael B.A.

“…To study the effect of cell type-restricted hamster PrP expression on susceptibility to the hamster scrapie agent, we generated transgenic mice using a 1 kb…”
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Comparative analysis of scrapie agent inactivation methods by Ernst, D R, Race, R E

“…A scrapie-infected hamster brain homogenate was subjected to several different potential inactivation methods. Methods included autoclaving for various lengths…”
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N-terminal truncation of the scrapie-associated form of PrP by lysosomal protease(s): implications regarding the site of conversion of PrP to the protease-resistant state by Caughey, B. (National Institute of Allergy and Infectious Diseases, Hamilton, MT), Raymond, G.J, Ernst, D, Race, R.E

“…Scrapie and related transmissible spongiform encephalopathies result in the accumulation of a protease-resistant form of an endogenous brain protein called…”
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Congo red inhibition of scrapie agent replication by CAUGHEY, B, ERNST, D, RACE, R. E

“…Congo red inhibits the accumulation of protease-resistant PrP in scrapie-infected mouse neuroblastoma cells. Here we show that Congo red also inhibits the…”
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Detection of proteinase K-resistant prion protein and infectivity in mouse spleen by 2 weeks after scrapie agent inoculation by Race, Richard E, Ernst, Darwin

“…National Institutes of Health, National Institute of Allergy and Infectious Diseases, Laboratory of Persistent Viral Diseases, Rocky Mountain Laboratories,…”
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Normal and scrapie-associated forms of prion protein differ in their sensitivities to phospholipase and proteases in intact neuroblastoma cells by CAUGHEY, B, NEARY, K, BULLER, R, ERNST, D, PERRY, L. L, CHESEBRO, B, RACE, R. E

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Detection of prion protein in formalin-fixed brain by hydrated autoclaving immunohistochemistry for the diagnosis of scrapie in sheep by Miller, J M, Jenny, A L, Taylor, W D, Race, R E, Ernst, D R, Katz, J B, Rubenstein, R

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Diagnostic implications of detection of proteinase K-resistant protein in spleen, lymph nodes, and brain of sheep by Race, R, Ernst, D, Jenny, A, Taylor, W, Sutton, D, Caughey, B

“…Brain, spleen, and selected lymph nodes from sheep with clinical signs of scrapie were analyzed for presence of proteinase K-resistant protein (PrP-res)…”
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Analysis of linkage between scrapie incubation period and the prion protein gene in mice by Race, Richard E, Graham, Kenneth, Ernst, Darwin, Caughey, Byron, Chesebro, Bruce

“…National Institutes of Health, National Institute of Allergy and Infectious Diseases, Laboratory of Persistent Viral Diseases, Rocky Mountain Laboratories,…”
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Severe autolysis does not prevent scrapie diagnosis in sheep by Race, R E, Ernst, D, Sutton, D

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Protease sensitivity and nuclease resistance of the scrapie agent propagated in vitro in neuroblastoma cells by Neary, K. (Fred Hutchinson Cancer Research Center, Seattle, WA), Caughey, B, Ernst, D, Race, R.E, Chesebro, B

“…The scrapie agent has been propagated in vitro in mouse neuroblastoma cells. To further characterize the tissue culture-derived scrapie agent, we studied the…”
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Secondary structure analysis of the scrapie-associated protein PrP 27-30 in water by infrared spectroscopy [Erratum to document cited in CA115(7):69556w] by Caughey, Byron W, Dong, Aichun, Bhat, Kolari S, Ernst, Darwin, Hayes, Stanley F, Caughey, Winslow S

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