Search Results - "Ernest, M."

SGLT2 and cancer by Wright, Ernest M.

“…Glycolysis plays a central role in tumor metabolism and growth, and this is reflected in a high rate of glucose uptake. It is commonly assumed that the…”
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Glucose transport families SLC5 and SLC50 by Wright, Ernest M.

“…There are three families of glucose transporters in the human genome, SLC2, SLC5 and SLC50. Here I review the structure and function of the SLC5 and SLC50…”
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Physiology of renal glucose handling via SGLT1, SGLT2 and GLUT2 by Ghezzi, Chiara, Loo, Donald D. F., Wright, Ernest M.

“…The concentration of glucose in plasma is held within narrow limits (4–10 mmol/l), primarily to ensure fuel supply to the brain. Kidneys play a role in glucose…”
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Environmental mercury and its toxic effects by Rice, Kevin M, Walker, Jr, Ernest M, Wu, Miaozong, Gillette, Chris, Blough, Eric R

“…Mercury exists naturally and as a man-made contaminant. The release of processed mercury can lead to a progressive increase in the amount of atmospheric…”
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SGLT2 Inhibitors: Physiology and Pharmacology by Wright, Ernest M

“…SGLTs are sodium glucose transporters found on the luminal membrane of the proximal tubule, where they reabsorb some 180 g (1 mol) of glucose from the…”
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Nanoparticle Aggregation: Challenges to Understanding Transport and Reactivity in the Environment by Hotze, Ernest M., Phenrat, Tanapon, Lowry, Gregory V.

“…Unique forms of manufactured nanomaterials, nanoparticles, and their suspensions are rapidly being created by manipulating properties such as shape, size,…”
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Biology of human sodium glucose transporters by Wright, Ernest M, Loo, Donald D F, Hirayama, Bruce A

“…There are two classes of glucose transporters involved in glucose homeostasis in the body, the facilitated transporters or uniporters (GLUTs) and the active…”
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Probing SGLT2 as a therapeutic target for diabetes: basic physiology and consequences by Gallo, Linda A, Wright, Ernest M, Vallon, Volker

“…Traditional treatments for type 1 and type 2 diabetes are often associated with side effects, including weight gain and hypoglycaemia that may offset the…”
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The dynamic relationship between CEO duality and firm performance: The moderating role of board independence by Duru, Augustine, Iyengar, Raghavan J., Zampelli, Ernest M.

“…For a panel of U.S. firms, we employ system GMM to estimate a dynamic model of the relationship between firm performance and governance characteristics…”
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Correction to: SGLT2 and cancer by Wright, Ernest M.

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Functional expression of sodium-glucose transporters in cancer by Scafoglio, Claudio, Bruce A. Hirayama, Vladimir Kepe, Jie Liu, Chiara Ghezzi, Nagichettiar Satyamurthy, Neda A. Moatamed, Jiaoti Huang, Hermann Koepsell, Jorge R. Barrio, Ernest M. Wright

“…Glucose is a major metabolic substrate required for cancer cell survival and growth. It is mainly imported into cells by facilitated glucose transporters…”
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Regulation of the human Na+-dependent glucose cotransporter hSGLT2 by Ghezzi, Chiara, Wright, Ernest M

“…The human Na(+)-glucose cotransporter SGLT2 is expressed mainly in the kidney proximal convoluted tubule where it is considered to be responsible for the bulk…”
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Structure and function of Na +-symporters with inverted repeats by Abramson, Jeff, Wright, Ernest M

“…Symporters are membrane proteins that couple energy stored in electrochemical potential gradients to drive the cotransport of molecules and ions into cells…”
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Wind energy, the price of carbon allowances, and CO2 emissions: Evidence from Ireland by Forbes, Kevin F., Zampelli, Ernest M.

“…Increased reliance on renewable energy is an important component of the European Union's action plan for reducing carbon emissions. Another key instrument is…”
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Assisted reproductive technology: Short‐ and long‐term outcomes by Graham, Mary Elaine, Jelin, Angie, Hoon, Alexander H., Wilms Floet, Anna Maria, Levey, Eric, Graham, Ernest M.

“…Assisted reproductive technology (ART) includes fertility treatment in which either eggs or embryos are handled outside a female's body to promote successful…”
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Novel and Unexpected Functions of SGLTs by Wright, Ernest M, Ghezzi, Chiara, Loo, Donald D F

“…It has been 30 years since the intestinal sodium glucose cotransporter SGLT1 was cloned, and, in the intervening years, there have been many advances that have…”
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A systematic review of the role of intrapartum hypoxia-ischemia in the causation of neonatal encephalopathy by Graham, Ernest M., MD, Ruis, Kristy A., MD, Hartman, Adam L., MD, Northington, Frances J., MD, Fox, Harold E., MD, MSc

“…The object of this review was to determine the incidence, morbidity, and mortality of an umbilical arterial pH < 7.0; the incidence of hypoxic-ischemic…”
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Function Trumps Form in Two Sugar Symporters, LacY and vSGLT by Abramson, Jeff, Wright, Ernest M

“…Active transport of sugars into bacteria occurs through symporters driven by ion gradients. is the most well-studied proton sugar symporter, whereas is the…”
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Comparative Photoactivity and Antibacterial Properties of C60 Fullerenes and Titanium Dioxide Nanoparticles by Brunet, Léna, Lyon, Delina Y, Hotze, Ernest M, Alvarez, Pedro J. J, Wiesner, Mark R

“…The production of reactive oxygen species (ROS) by aqueous suspensions of fullerenes and nano-TiO2 (Degussa P25) was measured both in ultrapure water and in…”
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SurvLIME: A method for explaining machine learning survival models by Kovalev, Maxim S., Utkin, Lev V., Kasimov, Ernest M.

“…A new method called SurvLIME for explaining machine learning survival models is proposed. It can be viewed as an extension or modification of the well-known…”
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