Search Results - "Ernest, Jan"
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CAM: Causal additive models, high-dimensional order search and penalized regression
Published in The Annals of statistics (01-12-2014)Get full text
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Biosimilar SB15 versus reference aflibercept in neovascular age-related macular degeneration: 1-year and switching results of a phase 3 clinical trial
Published in BMJ open ophthalmology (19-12-2023)“…Background/aimsTo evaluate efficacy, safety, pharmacokinetics (PK) and immunogenicity of SB15 versus reference aflibercept (AFL), and switching from AFL to…”
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Prophylactic use of dural tenting sutures in elective craniotomies in adults-is it necessary? A study protocol for a multicentre, investigator- and participant-blinded randomised, parallel-group, non-inferiority trial
Published in Current controlled trials in cardiovascular medicine (12-04-2021)“…In the early days of neurosurgery, extradural haemorrhages (EDHs) contributed to a high mortality rate after craniotomies. Almost a century ago, Walter Dandy…”
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4
Three cases of ectopic sphenoid sinus pituitary adenoma
Published in Folia neuropathologica (01-01-2017)“…Introduction: Ectopic sphenoid sinus pituitary adenoma is a rare tumour originating from embryologic remnants of Rathke's pouch. Although it is considered a…”
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Stereotactic Radiotherapy for Neovascular Age-related Macular Degeneration
Published in Ophthalmology (Rochester, Minn.) (01-09-2013)“…Purpose To determine the safety and efficacy of low-voltage, external-beam, stereotactic radiotherapy (SRT) for patients with neovascular age-related macular…”
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CAM: CAUSAL ADDITIVE MODELS, HIGH-DIMENSIONAL ORDER SEARCH AND PENALIZED REGRESSION
Published in The Annals of statistics (01-12-2014)“…We develop estimation for potentially high-dimensional additive structural equation models. A key component of our approach is to decouple order search among…”
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CAUSAL INFERENCE IN PARTIALLY LINEAR STRUCTURAL EQUATION MODELS
Published in The Annals of statistics (01-12-2018)“…We consider identifiability of partially linear additive structural equation models with Gaussian noise (PLSEMs) and estimation of distributionally equivalent…”
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Efficacy and Safety of a Proposed Ranibizumab Biosimilar Product vs a Reference Ranibizumab Product for Patients With Neovascular Age-Related Macular Degeneration: A Randomized Clinical Trial
Published in JAMA ophthalmology (01-01-2021)“…Neovascular age-related macular degeneration is the leading cause of blindness in individuals 50 years or older. The availability of a ranibizumab biosimilar…”
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Efficacy and Safety of the Aflibercept Biosimilar SB15 in Neovascular Age-Related Macular Degeneration: A Phase 3 Randomized Clinical Trial
Published in JAMA ophthalmology (01-07-2023)“…Aflibercept biosimilars can expand available treatment options in retinal diseases and have the potential to improve patient access to safe and effective…”
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Biosimilar SB11 versus reference ranibizumab in neovascular age-related macular degeneration: 1-year phase III randomised clinical trial outcomes
Published in British journal of ophthalmology (01-03-2023)“…To provide longer-term data on efficacy, safety, immunogenicity and pharmacokinetics (PK) of ranibizumab biosimilar SB11 compared with the reference…”
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Anatomical and Radiological Analysis of Structures of Petrous Part of the Temporal Bone and Their Impact on Area of Anterior Petrosectomy
Published in World neurosurgery (01-09-2024)“…Anterior petrosectomy (AP) is a commonly recognized approach for accessing tumors located in the petrous apex region. The essence of AP lies in drilling the…”
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Vogt-Koyanagi-Harada Syndrome (Uveomeningoencephalitic Syndrome)
Published in European journal of ophthalmology (01-01-2017)“…Purpose To report a case of a 29-year-old man who was examined at the Eye Clinic of Central Military University Hospital Prague for a severe headache and acute…”
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Faricimab Treat-and-Extend for Diabetic Macular Edema
Published in Ophthalmology (Rochester, Minn.) (01-06-2024)“…To evaluate the 2-year efficacy, durability, and safety of dual angiopoietin-2 and vascular endothelial growth factor (VEGF) A pathway inhibition with…”
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RETROSPECTIVE ANALYSIS OF THE PRESENCE OF CHOROIDAL NEOVASCULARISATION USING OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY IN THE TREATMENT OF CHRONIC CENTRAL SEROUS CHORIORETINOPATHY WITH THE AID OF PHOTODYNAMIC THERAPY
Published in Česká a slovenská oftalmologie (2021)“…Analysis of the presence of choroidal neovascularization (CNV) by optical coherence tomography angiography (OCTA) in eyes treated with photodynamic therapy in…”
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Intravitreal aflibercept 8 mg in diabetic macular oedema (PHOTON): 48-week results from a randomised, double-masked, non-inferiority, phase 2/3 trial
Published in The Lancet (British edition) (23-03-2024)“…A high-dose formulation of intravitreal aflibercept (8 mg) could improve treatment outcomes in diabetic macular oedema (DMO) by requiring fewer injections than…”
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Intravitreal Aflibercept for Neovascular Age-Related Macular Degeneration Beyond One Year of Treatment: AZURE, a Randomized Trial of Treat-and-Extend vs. Fixed Dosing
Published in Advances in therapy (01-03-2024)“…Introduction AZURE was a 76-week, randomized, open-label, parallel-group, phase IIIb noninferiority study comparing the efficacy and safety of intravitreal…”
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Suprasellar Epidermoid Cyst: Case Report of Extended Endoscopic Transsphenoidal Resection and Systematic Review of the Literature
Published in World neurosurgery (01-08-2019)“…Suprasellar epidermoid cysts (SECs) constitute a large portion of so-called pearly tumors. Despite their insidious development and infiltration into vital…”
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SCHEMES WITH WELL-CONTROLLED DISSIPATION
Published in SIAM journal on numerical analysis (01-01-2015)“…We design schemes for the approximation of entropy solutions to nonlinear hyperbolic conservation laws in the regime where small-scale effects drive the…”
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Aflibercept Biosimilar MYL-1701P vs Reference Aflibercept in Diabetic Macular Edema: The INSIGHT Randomized Clinical Trial
Published in JAMA ophthalmology (01-10-2024)“…Biosimilars may be lower-cost alternatives to originator biologic products, potentially offering expanded access or reduced economic burden, but have not been…”
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Validation of the Elderly Traumatic Brain Injury Score: Observational Case Control Study
Published in World neurosurgery (01-05-2022)“…Traumatic brain injury (TBI) poses a particular health risk for the elderly. The recently developed elderly TBI (eTBI) score combines the prognostic…”
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