Search Results - "Ermakova, Yulia G"
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Fluorescent ratiometric pH indicator SypHer2: Applications in neuroscience and regenerative biology
Published in Biochimica et biophysica acta (01-11-2015)“…SypHer is a genetically encoded fluorescent pH-indicator with a ratiometric readout, suitable for measuring fast intracellular pH shifts. However, the…”
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Thermogenetic neurostimulation with single-cell resolution
Published in Nature communications (22-05-2017)“…Thermogenetics is a promising innovative neurostimulation technique, which enables robust activation of neurons using thermosensitive transient receptor…”
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Slowly Reducible Genetically Encoded Green Fluorescent Indicator for In Vivo and Ex Vivo Visualization of Hydrogen Peroxide
Published in International journal of molecular sciences (27-06-2019)“…Hydrogen peroxide (H O ) plays an important role in modulating cell signaling and homeostasis in live organisms. The HyPer family of genetically encoded…”
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Red fluorescent redox-sensitive biosensor Grx1-roCherry
Published in Redox biology (01-02-2019)“…Redox-sensitive fluorescent proteins (roFPs) are a powerful tool for imaging intracellular redox changes. The structure of these proteins contains a pair of…”
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Ultrasensitive Genetically Encoded Indicator for Hydrogen Peroxide Identifies Roles for the Oxidant in Cell Migration and Mitochondrial Function
Published in Cell metabolism (03-03-2020)“…Hydrogen peroxide (H2O2) is a key redox intermediate generated within cells. Existing probes for H2O2 have not solved the problem of detection of the ultra-low…”
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Red fluorescent genetically encoded indicator for intracellular hydrogen peroxide
Published in Nature communications (21-10-2014)“…Reactive oxygen species (ROS) are conserved regulators of numerous cellular functions, and overproduction of ROS is a hallmark of various pathological…”
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HyPer-3: A Genetically Encoded H2O2 Probe with Improved Performance for Ratiometric and Fluorescence Lifetime Imaging
Published in ACS chemical biology (15-03-2013)“…High-performance sensors for reactive oxygen species are instrumental to monitor dynamic events in cells and organisms. Here, we present HyPer-3, a genetically…”
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Pyridinium Analogues of Green Fluorescent Protein Chromophore: Fluorogenic Dyes with Large Solvent-Dependent Stokes Shift
Published in The journal of physical chemistry letters (19-04-2018)“…Novel fluorogenic dyes based on the GFP chromophore are developed. The compounds contain a pyridinium ring instead of phenolate and feature large Stokes shifts…”
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Visualization of Intracellular Hydrogen Peroxide with the Genetically Encoded Fluorescent Probe HyPer in NIH-3T3 Cells
Published in Methods in molecular biology (Clifton, N.J.) (2019)“…Reactive oxygen species (ROS) are involved in regulating normal physiological cell functions as second messengers as well as nonspecific damage of biomolecules…”
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Human TRPV1 is an efficient thermogenetic actuator for chronic neuromodulation
Published in Cellular and molecular life sciences : CMLS (01-12-2024)“…Thermogenetics is a promising neuromodulation technique based on the use of heat-sensitive ion channels. However, on the way to its clinical application, a…”
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The ‘mitoflash’ probe cpYFP does not respond to superoxide
Published in Nature (London) (23-10-2014)“…Arising from E.-Z. Shen et al. Nature508, 128–132 (2014); doi:10.1038/nature1301210.1038/nature13012 Ageing and lifespan of organisms are determined by…”
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Pyridine analogue of fluorescent protein chromophore: Fluorogenic dye suitable for mitochondria staining
Published in Dyes and pigments (01-11-2019)“…In this paper, we present a novel fluorogenic analogue of the GFP chromophore with atypical solvent-dependent variations of the fluorescence quantum yield…”
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Thermogenetic stimulation of single neocortical pyramidal neurons transfected with TRPV1-L channels
Published in Neuroscience letters (20-11-2018)“…•Functional TRPV1-L channels can be expressed in pyramidal cells of mouse neocortex using in utero electroporation.•IR (infrared) radiation induces membrane…”
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In vivo dynamics of acidosis and oxidative stress in the acute phase of an ischemic stroke in a rodent model
Published in Redox biology (01-12-2021)“…Ischemic cerebral stroke is one of the leading causes of death and disability in humans. However, molecular processes underlying the development of this…”
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Two‐ and three‐photon absorption cross‐section characterization for high‐brightness, cell‐specific multiphoton fluorescence brain imaging
Published in Journal of biophotonics (01-03-2020)“…We demonstrate an accurate quantitative characterization of absolute two‐ and three‐photon absorption (2PA and 3PA) action cross sections of a genetically…”
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The 'mitoflash' probe cpYFP does not respond to superoxide/Cheng et al. reply
Published in Nature (London) (23-10-2014)“…Exposure of cpYFP to a superoxide-generating system (xanthine (X) and xanthine oxidase (XO)) slightly changed the excitation and emission spectra.However, the…”
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HyPer-3: A Genetically Encoded H 2 O 2 Probe with Improved Performance for Ratiometric and Fluorescence Lifetime Imaging
Published in ACS chemical biology (15-03-2013)Get full text
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HyPer-3: a genetically encoded H(2)O(2) probe with improved performance for ratiometric and fluorescence lifetime imaging
Published in ACS chemical biology (15-03-2013)“…High-performance sensors for reactive oxygen species are instrumental to monitor dynamic events in cells and organisms. Here, we present HyPer-3, a genetically…”
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