Search Results - "Erli, Filippo"

Development of Diphenethylamines as Selective Kappa Opioid Receptor Ligands and Their Pharmacological Activities by Schmidhammer, Helmut, Erli, Filippo, Guerrieri, Elena, Spetea, Mariana

“…Among the opioid receptors, the kappa opioid receptor (KOR) has been gaining substantial attention as a promising molecular target for the treatment of…”
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Identification and characterization of plant-derived alkaloids, corydine and corydaline, as novel mu opioid receptor agonists by Kaserer, Teresa, Steinacher, Theresa, Kainhofer, Roman, Erli, Filippo, Sturm, Sonja, Waltenberger, Birgit, Schuster, Daniela, Spetea, Mariana

“…Pain remains a key therapeutic area with intensive efforts directed toward finding effective and safer analgesics in light of the ongoing opioid crisis…”
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Estradiol reverses excitatory synapse loss in a cellular model of neuropsychiatric disorders by Erli, Filippo, Palmos, Alish B., Raval, Pooja, Mukherjee, Jayanta, Sellers, Katherine J., Gatford, Nicholas J. F., Moss, Stephen J., Brandon, Nicholas J., Penzes, Peter, Srivastava, Deepak P.

“…Loss of glutamatergic synapses is thought to be a key cellular pathology associated with neuropsychiatric disorders including schizophrenia (SCZ) and major…”
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In Vitro, In Vivo and In Silico Characterization of a Novel Kappa-Opioid Receptor Antagonist by Puls, Kristina, Olivé-Marti, Aina-Leonor, Pach, Szymon, Pinter, Birgit, Erli, Filippo, Wolber, Gerhard, Spetea, Mariana

“…Kappa-opioid receptor (KOR) antagonists are promising innovative therapeutics for the treatment of the central nervous system (CNS) disorders. The new scaffold…”
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Rapid modulation of synaptogenesis and spinogenesis by 17β-estradiol in primary cortical neurons by Sellers, Katherine J., Erli, Filippo, Raval, Pooja, Watson, Iain A., Chen, Ding, Srivastava, Deepak P.

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Highly Potent and Selective New Diphenethylamines Interacting with the κ‑Opioid Receptor: Synthesis, Pharmacology, and Structure–Activity Relationships by Erli, Filippo, Guerrieri, Elena, Ben Haddou, Tanila, Lantero, Aquilino, Mairegger, Michael, Schmidhammer, Helmut, Spetea, Mariana

“…We previously reported on a series of small molecules targeting the κ-opioid (KOP) receptor featuring a diphenethylamine scaffold and showed the promise of…”
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Rapid modulation of synaptogenesis and spinogenesis by 17β-estradiol in primary cortical neurons by Sellers, Katherine J, Erli, Filippo, Raval, Pooja, Watson, Iain A, Chen, Ding, Srivastava, Deepak P

“…In the mammalian forebrain, the majority of excitatory synapses occur on dendritic spines. Changes in the number of these structures is important for brain…”
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