Search Results - "Erlank, Erica"

The importance of morphological identification of African anopheline mosquitoes (Diptera: Culicidae) for malaria control programmes by Erlank, Erica, Koekemoer, Lizette L, Coetzee, Maureen

“…The correct identification of disease vectors is the first step towards implementing an effective control programme. Traditionally, for malaria control, this…”
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Multistage and transmission-blocking targeted antimalarials discovered from the open-source MMV Pandemic Response Box by Reader, Janette, van der Watt, Mariëtte E., Taylor, Dale, Le Manach, Claire, Mittal, Nimisha, Ottilie, Sabine, Theron, Anjo, Moyo, Phanankosi, Erlank, Erica, Nardini, Luisa, Venter, Nelius, Lauterbach, Sonja, Bezuidenhout, Belinda, Horatscheck, Andre, van Heerden, Ashleigh, Spillman, Natalie J., Cowell, Anne N., Connacher, Jessica, Opperman, Daniel, Orchard, Lindsey M., Llinás, Manuel, Istvan, Eva S., Goldberg, Daniel E., Boyle, Grant A., Calvo, David, Mancama, Dalu, Coetzer, Theresa L., Winzeler, Elizabeth A., Duffy, James, Koekemoer, Lizette L., Basarab, Gregory, Chibale, Kelly, Birkholtz, Lyn-Marié

“…Chemical matter is needed to target the divergent biology associated with the different life cycle stages of Plasmodium . Here, we report the parallel de novo…”
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The ecdysone receptor regulates several key physiological factors in Anopheles funestus by Maharaj, Surina, Ekoka, Elodie, Erlank, Erica, Nardini, Luisa, Reader, Janette, Birkholtz, Lyn-Marie, Koekemoer, Lizette L

“…Malaria is a devastating disease, transmitted by female Anopheles mosquitoes infected with Plasmodium parasites. Current insecticide-based strategies exist to…”
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Standard Membrane Feeding Assay for the Detection of Plasmodium falciparum Infection in Anopheles Mosquito Vectors by Erlank, Erica, Venter, Nelius, Koekemoer, Lizette L

“…Malaria remains one of the most devastating diseases worldwide and, to date, the African region is still responsible for 94% of all cases worldwide. This…”
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Effectiveness of reactive focal mass drug administration and reactive focal vector control to reduce malaria transmission in the low malaria-endemic setting of Namibia: a cluster-randomised controlled, open-label, two-by-two factorial design trial by Hsiang, Michelle S, Ntuku, Henry, Roberts, Kathryn W, Dufour, Mi-Suk Kang, Whittemore, Brooke, Tambo, Munyaradzi, McCreesh, Patrick, Medzihradsky, Oliver F, Prach, Lisa M, Siloka, Griffith, Siame, Noel, Gueye, Cara Smith, Schrubbe, Leah, Wu, Lindsey, Scott, Valerie, Tessema, Sofonias, Greenhouse, Bryan, Erlank, Erica, Koekemoer, Lizette L, Sturrock, Hugh J W, Mwilima, Agnes, Katokele, Stark, Uusiku, Petrina, Bennett, Adam, Smith, Jennifer L, Kleinschmidt, Immo, Mumbengegwi, Davis, Gosling, Roly

“…In low malaria-endemic settings, screening and treatment of individuals in close proximity to index cases, also known as reactive case detection (RACD), is…”
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The anticancer human mTOR inhibitor sapanisertib potently inhibits multiple Plasmodium kinases and life cycle stages by Arendse, Lauren B, Murithi, James M, Qahash, Tarrick, Pasaje, Charisse Flerida A, Godoy, Luiz C, Dey, Sumanta, Gibhard, Liezl, Ghidelli-Disse, Sonja, Drewes, Gerard, Bantscheff, Marcus, Lafuente-Monasterio, Maria J, Fienberg, Stephen, Wambua, Lynn, Gachuhi, Samuel, Coertzen, Dina, van der Watt, Mariëtte, Reader, Janette, Aswat, Ayesha S, Erlank, Erica, Venter, Nelius, Mittal, Nimisha, Luth, Madeline R, Ottilie, Sabine, Winzeler, Elizabeth A, Koekemoer, Lizette L, Birkholtz, Lyn-Marie, Niles, Jacquin C, Llinás, Manuel, Fidock, David A, Chibale, Kelly

“…Compounds acting on multiple targets are critical to combating antimalarial drug resistance. Here, we report that the human "mammalian target of rapamycin"…”
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The Tuberculosis Drug Candidate SQ109 and Its Analogs Have Multistage Activity against Plasmodium falciparum by Watson, Savannah J., van der Watt, Mariëtte E., Theron, Anjo, Reader, Janette, Tshabalala, Sizwe, Erlank, Erica, Koekemoer, Lizette L., Naude, Mariska, Stampolaki, Marianna, Adewole, Feyisola, Sadowska, Katie, Pérez-Lozano, Pilar, Turcu, Andreea L., Vázquez, Santiago, Ko, Jihee, Mazurek, Ben, Singh, Davinder, Malwal, Satish R., Njoroge, Mathew, Chibale, Kelly, Onajole, Oluseye K., Kolocouris, Antonios, Oldfield, Eric, Birkholtz, Lyn-Marié

“…Toward repositioning the antitubercular clinical candidate SQ109 as an antimalarial, analogs were investigated for structure–activity relationships for…”
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Benzimidazole Derivatives Are Potent against Multiple Life Cycle Stages of Plasmodium falciparum Malaria Parasites by Leshabane, Meta, Dziwornu, Godwin Akpeko, Coertzen, Dina, Reader, Janette, Moyo, Phanankosi, van der Watt, Mariëtte, Chisanga, Kelly, Nsanzubuhoro, Consolata, Ferger, Richard, Erlank, Erica, Venter, Nelius, Koekemoer, Lizette, Chibale, Kelly, Birkholtz, Lyn-Marie

“…The continued emergence of resistance to front-line antimalarial treatments is of great concern. Therefore, new compounds that potentially have a novel target…”
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