Search Results - "Erlandsson, Malin"

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    Bone remodelling: locus minori or unappreciated potential of tofacitinib? by Bokarewa, Maria I, Erlandsson, Malin C

    Published in Rheumatology (Oxford, England) (01-08-2018)
    “…This editorial refers to the article "Effects of tofacitinib in early arthritis-induced bone loss in an adjuvant-induced arthritis rat model" by Bruno Vidal et…”
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    Ex Vivo Vascular Imaging and Perfusion Studies of Normal Kidney and Tumor Vasculature by Hultborn, Ragnar, Weiss, Lilian, Tveit, Egil, Lange, Stefan, Jennische, Eva, Erlandsson, Malin C, Johansson, Martin E

    Published in Cancers (20-05-2024)
    “…This work describes a comprehensive study of the vascular tree and perfusion characteristics of normal kidney and renal cell carcinoma. Methods: Nephrectomy…”
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    Prognostic Significance of BIRC5/Survivin in Breast Cancer: Results from Three Independent Cohorts by Oparina, Nina, Erlandsson, Malin C., Fäldt Beding, Anna, Parris, Toshima, Helou, Khalil, Karlsson, Per, Einbeigi, Zakaria, Bokarewa, Maria I.

    Published in Cancers (04-05-2021)
    “…Breast cancer (BC) histological and molecular classifications significantly improved the treatment strategy and prognosis. Inhibitor of apoptosis…”
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    IGF-1R signalling contributes to IL-6 production and T cell dependent inflammation in rheumatoid arthritis by Erlandsson, Malin C., Töyrä Silfverswärd, Sofia, Nadali, Mitra, Turkkila, Minna, Svensson, Mattias N.D., Jonsson, Ing-Marie, Andersson, Karin M.E., Bokarewa, Maria I.

    “…Signalling through insulin-like growth factor 1 receptor (IGF-1R) is essential for cell survival, but may turn pathogenic in uncontrolled tissue growth in…”
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    Radiological features of experimental staphylococcal septic arthritis by micro computed tomography scan by Fatima, Farah, Fei, Ying, Ali, Abukar, Mohammad, Majd, Erlandsson, Malin C, Bokarewa, Maria I, Nawaz, Muhammad, Valadi, Hadi, Na, Manli, Jin, Tao

    Published in PloS one (02-02-2017)
    “…Permanent joint dysfunction due to bone destruction occurs in up to 50% of patients with septic arthritis. Recently, imaging technologies such as micro…”
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    Metabolic signature and proteasome activity controls synovial migration of CDC42hiCD14+ cells in rheumatoid arthritis by Malmhäll-Bah, Eric, Andersson, Karin M.E., Erlandsson, Malin C., Silfverswärd, Sofia T., Pullerits, Rille, Bokarewa, Maria I.

    Published in Frontiers in immunology (2023)
    “…Objective Activation of Rho-GTPases in macrophages causes inflammation and severe arthritis in mice. In this study, we explore if Rho-GTPases define the joint…”
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    Chronic hyperinsulinemia promotes human hepatocyte senescence by Baboota, Ritesh K., Spinelli, Rosa, Erlandsson, Malin C., Brandao, Bruna B., Lino, Marsel, Yang, Hong, Mardinoglu, Adil, Bokarewa, Maria I., Boucher, Jeremie, Kahn, C. Ronald, Smith, Ulf

    Published in Molecular metabolism (Germany) (01-10-2022)
    “…Cellular senescence, an irreversible proliferative cell arrest, is caused by excessive intracellular or extracellular stress/damage. Increased senescent cells…”
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    IGF1R signalling is a guardian of self-tolerance restricting autoantibody production by Erlandsson, Malin C., Erdogan, Seval, Wasén, Caroline, Andersson, Karin M. E., Silfverswärd, Sofia T., Pullerits, Rille, Bemark, Mats, Bokarewa, Maria I.

    Published in Frontiers in immunology (29-08-2022)
    “…Objective Insulin-like growth factor 1 receptor (IGF1R) acts at the crossroad between immunity and cancer, being an attractive therapeutic target in these…”
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    Low serum IGF1 is associated with hypertension and predicts early cardiovascular events in women with rheumatoid arthritis by Erlandsson, Malin C, Lyngfelt, Lovisa, Åberg, N David, Wasén, Caroline, Espino, Rachelle A, Silfverswärd, Sofia Töyrä, Nadali, Mitra, Jood, Katharina, Andersson, Karin M E, Pullerits, Rille, Bokarewa, Maria I

    Published in BMC medicine (22-07-2019)
    “…Since low insulin-like growth factor (IGF) 1 is often linked to inflammation, we analyze whether serum levels of IGF1 are associated with cardiovascular…”
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    MicroRNA and interleukin 6 interplay in the adipose tissue of rheumatoid arthritis patients by Larsson, Carolina, Andersson, Karin M E, Nadali, Mitra, Silfverswärd, Sofia T, Bokarewa, Maria I, Erlandsson, Malin C

    Published in Clinical and experimental rheumatology (01-01-2023)
    “…MicroRNAs (miRs) are non-translated RNA sequences that elicit negative control over protein expression. The adipose tissue (AT) is considered the major…”
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    Nicotine Changes the microRNA Profile to Regulate the FOXO Memory Program of CD8 + T Cells in Rheumatoid Arthritis by Wasén, Caroline, Ospelt, Caroline, Camponeschi, Alessandro, Erlandsson, Malin C, Andersson, Karin M E, Silfverswärd, Sofia Töyrä, Gay, Steffen, Bokarewa, Maria I

    Published in Frontiers in immunology (14-07-2020)
    “…Smoking suppresses PD-1 expression in patients with rheumatoid arthritis (RA). In this study, we assess if smoking changed the epigenetic control over CD8 T…”
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    Cohesin-Mediated Chromatin Interactions and Autoimmunity by Chandrasekaran, Venkataragavan, Oparina, Nina, Garcia-Bonete, Maria-Jose, Wasén, Caroline, Erlandsson, Malin C, Malmhäll-Bah, Eric, Andersson, Karin M E, Jensen, Maja, Silfverswärd, Sofia T, Katona, Gergely, Bokarewa, Maria I

    Published in Frontiers in immunology (10-02-2022)
    “…Proper physiological functioning of any cell type requires ordered chromatin organization. In this context, cohesin complex performs important functions…”
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    Rho-GTPase dependent leukocyte interaction generates pro-inflammatory thymic Tregs and causes arthritis by Malmhäll-Bah, Eric, Andersson, Karin M.E., Erlandsson, Malin C., Akula, Murali K., Brisslert, Mikael, Wiel, Clotilde, El Zowalaty, Ahmed E., Sayin, Volkan I., Bergö, Martin O., Bokarewa, Maria I.

    Published in Journal of autoimmunity (01-06-2022)
    “…Conditional mutation of protein geranylgeranyltransferase type I (GGTase-I) in macrophages (GLC) activates Rho-GTPases and causes arthritis in mice. Knocking…”
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    Inhibition of CCL3 abrogated precursor cell fusion and bone erosions in human osteoclast cultures and murine collagen-induced arthritis by Jordan, Lauren A, Erlandsson, Malin C, Fenner, Benjamin F, Davies, Ruth, Harvey, Ann K, Choy, Ernest H, Errington, Rachel, Bokarewa, Maria I, Williams, Anwen S

    Published in Rheumatology (Oxford, England) (01-11-2018)
    “…Abstract Objective Macrophage inflammatory protein 1-alpha (CCL3) is a chemokine that regulates macrophage trafficking to the inflamed joint. The agonistic…”
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    Immunomodulation by the estrogen metabolite 2-methoxyestradiol by Stubelius, Alexandra, Erlandsson, Malin C, Islander, Ulrika, Carlsten, Hans

    Published in Clinical immunology (Orlando, Fla.) (01-07-2014)
    “…Abstract 2-methoxyestradiol (2me2), a metabolite of 17β-estradiol (E2), has been tested in phase II clinical cancer trials and models of inflammation. Its…”
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    Protein prenylation restrains innate immunity by inhibiting Rac1 effector interactions by Akula, Murali K., Ibrahim, Mohamed X., Ivarsson, Emil G., Khan, Omar M., Kumar, Israiel T., Erlandsson, Malin, Karlsson, Christin, Xu, Xiufeng, Brisslert, Mikael, Brakebusch, Cord, Wang, Donghai, Bokarewa, Maria, Sayin, Volkan I., Bergo, Martin O.

    Published in Nature communications (04-09-2019)
    “…Rho family proteins are prenylated by geranylgeranyltransferase type I (GGTase-I), which normally target proteins to membranes for GTP-loading. However,…”
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    Effects of implant‐delivered insulin on bone formation in osteoporotic rats by Malekzadeh, Behnosh Ö., Erlandsson, Malin C., Tengvall, Pentti, Palmquist, Anders, Ransjo, Maria, Bokarewa, Maria I., Westerlund, Anna

    “…Osteoporosis is a major cause of age‐related fractures. Healing complications in osteoporotic patients are often associated with increased mortality and…”
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    High Expression of STAT3 in Subcutaneous Adipose Tissue Associates with Cardiovascular Risk in Women with Rheumatoid Arthritis by Nadali, Mitra, Pullerits, Rille, Andersson, Karin M E, Silfverswärd, Sofia Töyrä, Erlandsson, Malin C, Bokarewa, Maria I

    “…Despite the predominance of female patients and uncommon obesity, rheumatoid arthritis (RA) is tightly connected to increased cardiovascular morbidity. The aim…”
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