Search Results - "Erkell, L J"

Radiation-induced double-strand breaks in mammalian DNA: influence of temperature and DMSO by Elmroth, J. Nygren, L. J. Erkell, R. Hultborn, K.

“…Purpose : To investigate the effects of subphysiological irradiation temperature (2-28°C) and the influence of the radical scavenger DMSO on the induction of…”
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Influence of Temperature on Radiation-Induced Inhibition of DNA Supercoiling by Elmroth, K., Erkell, L. J., Hultborn, R.

“…The influence of subnormal temperatures (2, 15 and 28°C) on the effects of radiation in MCF-7 cell cultures was studied using the fluorescent (halo) nucleoid…”
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Effect of hypothermic irradiation of the growth characteristics of two human cell lines by Elmroth, K, Nygren, J, Erkell, L J, Hultborn, R

“…The effect of hypothermic irradiation on the growth characteristics of two human cell lines was investigated. Low temperature (2 degrees C) X-irradiation of…”
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Radiation and hypothermia: changes in DNA supercoiling in human diploid fibroblasts by Elmroth, K, Erkell, L J, Nygren, J, Hultborn, R

“…The influence of hypothermia (2 degrees, 15 degrees and 28 degrees C) upon the effect of X-irradiation on chromatin from human diploid fibroblast cells…”
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Sulfated glycosaminoglycans enhance tumor cell invasion in vitro by stimulating plasminogen activation by Brunner, G, Reimbold, K, Meissauer, A, Schirrmacher, V, Erkell, L J

“…Metastasizing tumor cells invade host tissues by degrading extracellular matrix constituents. We report here that the highly sulfated glycosaminoglycans,…”
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Photometric recording of cell viability using trypan blue in perfused cell cultures by Walum, E, Peterson, A, Erkell, L J

“…A perfusion system was developed to increase the reliability of cell viability estimations by continuous measurement of the uptake of trypan blue dye…”
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Induction of urokinase activity and malignant phenotype in bladder carcinoma cells after transfection of the activated Ha-ras oncogene by BRUNNER, G, POHL, J, ERKELL, L. J, RADLER-POHL, A, SCHIRRMACHER, V

“…In order to characterize further the previously observed induction of a highly metastatic phenotype in mouse bladder carcinoma cells by Ha-ras transfection, we…”
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Urokinase-type and tissue-type plasminogen activators are essential for in vitro invasion of human melanoma cells by Meissauer, A, Kramer, M D, Hofmann, M, Erkell, L J, Jacob, E, Schirrmacher, V, Brunner, G

“…This study evaluates the contribution of two types of plasminogen activators (PAs; tissue-type PA (tPA) versus urokinase-type PA (uPA) toward the invasiveness…”
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Quantitative in vitro assay for tumor cell invasion through extracellular matrix or into protein gels by ERKELL, L. J, SCHIRRMACHER, V

“…A new quantitative method for the study of tumor cell invasion in vitro is presented. It is intended to facilitate the study of the mechanisms of invasion…”
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Why do tumors metastasize? An overview of current research by Hagmar, B, Ryd, W, Erkell, L J

“…Current concepts relating to the genesis and establishment of metastases are reviewed. Attention is directed to the cell surface of tumor cells and the need to…”
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Methods in metastasis research. A critical review by Hagmar, B, Ryd, W, Erkell, L J

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Effects of zinc on tumor transplantability by Erkell, L J, Ryd, W, Hagmar, B

“…The effects of zinc treatment on the transplantability of tumor cells were investigated in two syngeneic murine tumor systems. A 15-min incubation of tumor…”
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The tumor-cell-releasing machine by Erkell, L J, Ryd, W, Hagmar, B

“…We describe the construction of a machine for the injection of 10- to 100-microliter volumes of viable cells in suspension. The cells are maintained in a…”
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Increased activity of a phospholipid base-exchange system by the differentiation of neoplastic cells from the nervous system by Erkell, L J, De Medio, G E, Haglid, K, Porcellati, G

“…The activity of a base-exchange enzyme system, specific for the polar head-groups of brain phospholipids, was measured in both C 1300 mouse neuroblastoma…”
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Synthesis and binding to tubulin of an allocolchicine spin probe by Deinum, J, Lincoln, P, Larsson, T, Lagercrantz, C, Erkell, L J

“…A spin probe for the colchicine binding site on tubulin has been synthesized from allocolchicine. The probe is competitive to colchicine with an apparent…”
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Metallothionein induction in rainbow trout gonadal (RTG-2) cells during free radical exposure by Kling, Peter, Erkell, Lars Johan, Kille, Peter, Olsson, Per-Erik

“…In the present study the free radical inducibility of the rainbow trout metallothionein-A (MT-A) gene was investigated. Earlier sequencing of the MT-A promoter…”
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Characterization of two murine tumor sublines selected purely in vivo for specific metastatic patterns by Ryd, W, Hagmar, B, Erkell, L J

“…We have attempted to clone an ascites tumor, MCB 21-AA, which was originally a fibrosarcoma, by transplantation of spontaneous metastases from the lungs or a…”
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Lectin binding in murine tumour lines with different malignant characteristics. Effect of enzyme (pronase, neuraminidase) treatment on lectin labelling by Hagmar, B, Erkell, L J, Burns, G, Ryd, W

“…We used 5 syngeneic murine tumour systems for studying quantitative lectin surface binding of intact viable tumour cells. We also investigated, for 3 of the…”
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Differences in membrane structure between suspended and attached mouse neuroblastoma cells by Erkell, Lars J.

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Effects of RA 233 treatment on the adhesive, invasive and metastatic properties of 13762NF rat mammary tumor cells by Lichtner, R B, Erkell, L J, Schirrmacher, V, Nicolson, G L

“…The pyrimido-pyrimidine analogue RA 233 has pleiotropic and differential effects on cultured tumor cell clones isolated from the 13762NF rat mammary…”
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