Search Results - "Erkelens, Amanda M"

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  1. 1

    Xenogeneic silencing strategies in bacteria are dictated by RNA polymerase promiscuity by Forrest, David, Warman, Emily A., Erkelens, Amanda M., Dame, Remus T., Grainger, David C.

    Published in Nature communications (03-03-2022)
    “…Horizontal gene transfer facilitates dissemination of favourable traits among bacteria. However, foreign DNA can also reduce host fitness: incoming sequences…”
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    Journal Article
  2. 2

    Mechanical and structural properties of archaeal hypernucleosomes by Henneman, Bram, Brouwer, Thomas B, Erkelens, Amanda M, Kuijntjes, Gert-Jan, van Emmerik, Clara, van der Valk, Ramon A, Timmer, Monika, Kirolos, Nancy C S, van Ingen, Hugo, van Noort, John, Dame, Remus T

    Published in Nucleic acids research (07-05-2021)
    “…Abstract Many archaea express histones, which organize the genome and play a key role in gene regulation. The structure and function of archaeal histone–DNA…”
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  3. 3

    Specific DNA binding of archaeal histones HMfA and HMfB by Erkelens, Amanda M, Henneman, Bram, van der Valk, Ramon A, Kirolos, Nancy C S, Dame, Remus T

    Published in Frontiers in microbiology (18-04-2023)
    “…In archaea, histones play a role in genome compaction and are involved in transcription regulation. Whereas archaeal histones bind DNA without sequence…”
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  4. 4

    DNA-bridging by an archaeal histone variant via a unique tetramerisation interface by Ofer, Sapir, Blombach, Fabian, Erkelens, Amanda M., Barker, Declan, Soloviev, Zoja, Schwab, Samuel, Smollett, Katherine, Matelska, Dorota, Fouqueau, Thomas, van der Vis, Nico, Kent, Nicholas A., Thalassinos, Konstantinos, Dame, Remus T., Werner, Finn

    Published in Communications biology (22-09-2023)
    “…In eukaryotes, histone paralogues form obligate heterodimers such as H3/H4 and H2A/H2B that assemble into octameric nucleosome particles. Archaeal histones are…”
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  5. 5

    System-Wide Analysis of the GATC-Binding Nucleoid-Associated Protein Gbn and Its Impact on Streptomyces Development by Du, Chao, Willemse, Joost, Erkelens, Amanda M, Carrion, Victor J, Dame, Remus T, van Wezel, Gilles P

    Published in mSystems (28-06-2022)
    “…Bacterial chromosome structure is, to a great extent, organized by a diverse group of proteins collectively referred to as nucleoid-associated proteins (NAPs)…”
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  6. 6

    Rok from B. subtilis: Bridging genome structure and transcription regulation by Erkelens, Amanda M, van Erp, Bert, Meijer, Wilfried J J, Dame, Remus T

    Published in Molecular microbiology (21-03-2024)
    “…Bacterial genomes are folded and organized into compact yet dynamic structures, called nucleoids. Nucleoid orchestration involves many factors at multiple…”
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  7. 7

    Mapping the transition state for a binding reaction between ancient intrinsically disordered proteins by Karlsson, Elin, Paissoni, Cristina, Erkelens, Amanda M., Tehranizadeh, Zeinab A., Sorgenfrei, Frieda A., Andersson, Eva, Ye, Weihua, Camilloni, Carlo, Jemth, Per

    Published in The Journal of biological chemistry (18-12-2020)
    “…Intrinsically disordered protein domains often have multiple binding partners. It is plausible that the strength of pairing with specific partners evolves from…”
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  8. 8

    The B. subtilis Rok protein is an atypical H-NS-like protein irresponsive to physico-chemical cues by Erkelens, Amanda M, Qin, Liang, van Erp, Bert, Miguel-Arribas, Andrés, Abia, David, Keek, Helena G J, Markus, Dorijn, Cajili, Marc K M, Schwab, Samuel, Meijer, Wilfried J J, Dame, Remus T

    Published in Nucleic acids research (28-11-2022)
    “…Nucleoid-associated proteins (NAPs) play a central role in chromosome organization and environment-responsive transcription regulation. The Bacillus…”
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  9. 9

    Novel anti-repression mechanism of H-NS proteins by a phage protein by Bdira, Fredj Ben, Erkelens, Amanda M, Qin, Liang, Volkov, Alexander N, Lippa, Andrew M, Bowring, Nicholas, Boyle, Aimee L, Ubbink, Marcellus, Dove, Simon L, Dame, Remus T

    Published in Nucleic acids research (11-10-2021)
    “…H-NS family proteins, bacterial xenogeneic silencers, play central roles in genome organization and in the regulation of foreign genes. It is thought that gene…”
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  10. 10

    Quantitation of DNA Binding Affinity Using Tethered Particle Motion by Henneman, Bram, Erkelens, Amanda M, Heinsman, Joost, Battjes, Julius, Dame, Remus T

    “…The binding constant is an important characteristic of a DNA-binding protein. A large number of methods exist to measure the binding constant, but many of…”
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  11. 11

    Mapping the transition state for a binding reaction between ancient intrinsically disordered proteins by Karlsson, Elin, Paissoni, Cristina, Erkelens, Amanda M., Tehranizadeh, Zeinab A., Sorgenfrei, Frieda A., Andersson, Eva, Ye, Weihua, Camilloni, Carlo, Jemth, Per

    Published in The Journal of biological chemistry (18-12-2020)
    “…Intrinsically disordered protein domains often have multiple binding partners. It is plausible that the strength of pairing with specific partners evolves from…”
    Get full text
    Journal Article
  12. 12

    Mapping the transition state for a binding reaction between ancient intrinsically disordered proteins by Karlsson, Elin, Paissoni, Cristina, Erkelens, Amanda M, Tehranizadeh, Zeinab A, Sorgenfrei, Frieda A, Andersson, Eva, Ye, Weihua, Camilloni, Carlo, Jemth, Per

    Published in The Journal of biological chemistry (18-12-2020)
    “…Intrinsically disordered protein domains often have multiple binding partners. It is plausible that the strength of pairing with specific partners evolves from…”
    Get full text
    Journal Article