Search Results - "Erkelens, Amanda M"
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Xenogeneic silencing strategies in bacteria are dictated by RNA polymerase promiscuity
Published in Nature communications (03-03-2022)“…Horizontal gene transfer facilitates dissemination of favourable traits among bacteria. However, foreign DNA can also reduce host fitness: incoming sequences…”
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2
Mechanical and structural properties of archaeal hypernucleosomes
Published in Nucleic acids research (07-05-2021)“…Abstract Many archaea express histones, which organize the genome and play a key role in gene regulation. The structure and function of archaeal histone–DNA…”
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Specific DNA binding of archaeal histones HMfA and HMfB
Published in Frontiers in microbiology (18-04-2023)“…In archaea, histones play a role in genome compaction and are involved in transcription regulation. Whereas archaeal histones bind DNA without sequence…”
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DNA-bridging by an archaeal histone variant via a unique tetramerisation interface
Published in Communications biology (22-09-2023)“…In eukaryotes, histone paralogues form obligate heterodimers such as H3/H4 and H2A/H2B that assemble into octameric nucleosome particles. Archaeal histones are…”
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System-Wide Analysis of the GATC-Binding Nucleoid-Associated Protein Gbn and Its Impact on Streptomyces Development
Published in mSystems (28-06-2022)“…Bacterial chromosome structure is, to a great extent, organized by a diverse group of proteins collectively referred to as nucleoid-associated proteins (NAPs)…”
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Rok from B. subtilis: Bridging genome structure and transcription regulation
Published in Molecular microbiology (21-03-2024)“…Bacterial genomes are folded and organized into compact yet dynamic structures, called nucleoids. Nucleoid orchestration involves many factors at multiple…”
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Mapping the transition state for a binding reaction between ancient intrinsically disordered proteins
Published in The Journal of biological chemistry (18-12-2020)“…Intrinsically disordered protein domains often have multiple binding partners. It is plausible that the strength of pairing with specific partners evolves from…”
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The B. subtilis Rok protein is an atypical H-NS-like protein irresponsive to physico-chemical cues
Published in Nucleic acids research (28-11-2022)“…Nucleoid-associated proteins (NAPs) play a central role in chromosome organization and environment-responsive transcription regulation. The Bacillus…”
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Novel anti-repression mechanism of H-NS proteins by a phage protein
Published in Nucleic acids research (11-10-2021)“…H-NS family proteins, bacterial xenogeneic silencers, play central roles in genome organization and in the regulation of foreign genes. It is thought that gene…”
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10
Quantitation of DNA Binding Affinity Using Tethered Particle Motion
Published in Methods in molecular biology (Clifton, N.J.) (2024)“…The binding constant is an important characteristic of a DNA-binding protein. A large number of methods exist to measure the binding constant, but many of…”
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11
Mapping the transition state for a binding reaction between ancient intrinsically disordered proteins
Published in The Journal of biological chemistry (18-12-2020)“…Intrinsically disordered protein domains often have multiple binding partners. It is plausible that the strength of pairing with specific partners evolves from…”
Get full text
Journal Article -
12
Mapping the transition state for a binding reaction between ancient intrinsically disordered proteins
Published in The Journal of biological chemistry (18-12-2020)“…Intrinsically disordered protein domains often have multiple binding partners. It is plausible that the strength of pairing with specific partners evolves from…”
Get full text
Journal Article