Search Results - "Eriksson, Lennart"

CV-ANOVA for significance testing of PLS and OPLS® models by Eriksson, Lennart, Trygg, Johan, Wold, Svante

“…This report describes significance testing for PLS and OPLS® (orthogonal PLS) models. The testing is applicable to single‐Y cases and is based on ANOVA of the…”
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Variable influence on projection (VIP) for OPLS models and its applicability in multivariate time series analysis by Galindo-Prieto, Beatriz, Eriksson, Lennart, Trygg, Johan

“…Recently a new parameter to infer variable importance in orthogonal projections to latent structures (OPLS) was presented. Called OPLS-VIP (variable influence…”
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A chemometrics toolbox based on projections and latent variables by Eriksson, Lennart, Trygg, Johan, Wold, Svante

“…A personal view is given about the gradual development of projection methods—also called bilinear, latent variable, and more—and their use in chemometrics. We…”
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Coated stainless steel as bipolar plate material for anion exchange membrane fuel cells (AEMFCs) by Proch, Sebastian, Stenström, Mikael, Eriksson, Lennart, Andersson, Jan, Sjöblom, Gustaf, Jansson, Anna, Westlinder, Jörgen

“…Low-temperature anion-exchange membrane fuel cells (AEMFCs) are gathering increased attention because they facilitate the use of non-precious metal catalysts,…”
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Mental Health, Culture and Resilience-Approaching the COVID-19 Pandemic From a South African Perspective by Mashaphu, Sibongile, Talatala, Mvuyiso, Seape, Sebolelo, Eriksson, Lennart, Chiliza, Bonginkosi

“…It is understandable that the challenges of living through a severe contagious outbreak, like the coronavirus disease 2019 (COVID-19), cannot be tolerated for…”
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Autopsies and quality of cause of death diagnoses by Rosendahl, Anders, Mjörnheim, Berit, Eriksson, Lennart C

“…Objective: The consequences of a low autopsy rate are not considered in determining the cause of death. Method: We have analyzed the Cause of Death Register of…”
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Methods for Reliability and Uncertainty Assessment and for Applicability Evaluations of Classification- and Regression-Based QSARs by Eriksson, Lennart, Jaworska, Joanna, Worth, Andrew P, Cronin, Mark T.D, McDowell, Robert M, Gramatica, Paola

“…This article provides an overview of methods for reliability assessment of quantitative structure-activity relationship (QSAR) models in the context of…”
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A randomization test for PLS component selection by Wiklund, Susanne, Nilsson, David, Eriksson, Lennart, Sjöström, Michael, Wold, Svante, Faber, Klaas

“…During the last two decades, a number of methods have been developed and evaluated for selecting the optimal number of components in a PLS model. In this…”
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typology of small-scale private forest owners in Sweden by Ingemarson, F, Lindhagen, A, Eriksson, L

“…Planning instruments have to be consistent with the underlying values of the forest owners to have an influence on their management activities. The aims of the…”
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Using chemometrics for navigating in the large data sets of genomics, proteomics, and metabonomics (gpm) by Eriksson, Lennart, Antti, Henrik, Gottfries, Johan, Holmes, Elaine, Johansson, Erik, Lindgren, Fredrik, Long, Ingrid, Lundstedt, Torbjörn, Trygg, Johan, Wold, Svante

“…This article describes the applicability of multivariate projection techniques, such as principal-component analysis (PCA) and partial least-squares (PLS)…”
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Antagonistic effects of selenium and lipid peroxides on growth control in early hepatocellular carcinoma by Rohr-Udilova, Nataliya, Sieghart, Wolfgang, Eferl, Robert, Stoiber, Dagmar, Björkhem-Bergman, Linda, Eriksson, Lennart C., Stolze, Klaus, Hayden, Hubert, Keppler, Bernhard, Sagmeister, Sandra, Grasl-Kraupp, Bettina, Schulte-Hermann, Rolf, Peck-Radosavljevic, Markus

“…Activation of the activator protein 1 (AP‐1) transcription factor as well as increased serum levels of vascular endothelial growth factor (VEGF) and…”
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Statins inhibit expression of Thioredoxin reductase 1 in rat and human liver and reduce tumour development by Skogastierna, Cristine, Johansson, Maria, Parini, Paolo, Eriksson, Mats, Eriksson, Lennart C., Ekström, Lena, Björkhem-Bergman, Linda

“…► Statins inhibits expression of Thioredoxin reductase 1 in rat and human liver tissue. ► Statin-mediated inhibition of Thioredoxin reductases may explain…”
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The effect of sodium selenite on liver growth and thioredoxin reductase expression in regenerative and neoplastic liver cell proliferation by Erkhembayar, Suvd, Mollbrink, Annelie, Eriksson, Lennart C.

“…Sodium selenite inhibits growth of liver tumours but not liver regeneration after partial hepatectomy (PH). An experimental rat study. Selenium in…”
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Attitudes of Nurses and Physicians About Clinical Autopsy in Neonatal and Adult Hospital Care: A Survey in Sweden by Mjörnheim, Berit, Rosendahl, Anders, Eriksson, Lennart C, Takman, Christina

“…BACKGROUNDThe rate of autopsies has dropped to low levels in Western countries. OBJECTIVEThe aim of this study was to describe the experiences and attitudes of…”
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New Chemical Descriptors Relevant for the Design of Biologically Active Peptides. A Multivariate Characterization of 87 Amino Acids by Sandberg, Maria, Eriksson, Lennart, Jonsson, Jörgen, Sjöström, Michael, Wold, Svante

“…In this study 87 amino acids (AA.s) have been characterized by 26 physicochemical descriptor variables. These descriptor variables include experimentally…”
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Megavariate analysis of environmental QSAR data. Part I--a basic framework founded on principal component analysis (PCA), partial least squares (PLS), and statistical molecular design (SMD) by Eriksson, Lennart, Andersson, Patrik L, Johansson, Erik, Tysklind, Mats

“…This paper introduces principal component analysis (PCA), partial least squares projections to latent structures (PLS), and statistical molecular design (SMD)…”
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The anti-carcinogenic effect of statins in a rat model correlates with levels and synthesis of ubiquinone by Acimovic, Jure, Lövgren-Sandblom, Anita, Eriksson, Lennart C., Björkhem-Bergman, Linda

“…► Ubiquinone levels correlates with inhibited carcinogenesis mediated by statins. ► Statin treatment leads to a shift to ubiquinone isoforms with shorter…”
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Lovastatin Prevents Carcinogenesis in a Rat Model for Liver Cancer. Effects of Ubiquinone Supplementation by BJÖRKHEM-BERGMAN, Linda, ACIMOVIC, Jure, TORNDAL, Ulla-Britta, PARINI, Paolo, ERIKSSON, Lennart C

“…This study tests the hypothesis that statins (HMGCoA reductase inhibitors) inhibit carcinogenesis and that this effect may be mediated by the statin-induced…”
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The mammalian cytosolic selenoenzyme thioredoxin reductase reduces ubiquinone. A novel mechanism for defense against oxidative stress by Xia, Ling, Nordman, Tomas, Olsson, Jerker M, Damdimopoulos, Anastassios, Björkhem-Bergman, Linda, Nalvarte, Ivan, Eriksson, Lennart C, Arnér, Elias S J, Spyrou, Giannis, Björnstedt, Mikael

“…The selenoprotein thioredoxin reductase (TrxR1) is an essential antioxidant enzyme known to reduce many compounds in addition to thioredoxin, its principle…”
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Iron-regulatory gene expression during liver regeneration by Mollbrink, Annelie, Holmström, Petra, Sjöström, Mattias, Hultcrantz, Rolf, Eriksson, Lennart C, Stål, Per

“…Abstract Background. In rat, the first 18-24 h after partial hepatectomy (PH) are characterized by an acute-phase reaction, after which liver regeneration…”
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